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    [{"orgOrder":0,"company":"Eisai","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"JAPAN","productType":"Small molecule","year":"2021","type":"Not Applicable","leadProduct":"Lenvatinib Mesylate","moa":"VEGFR","graph1":"Oncology","graph2":"Approved","graph3":"Eisai","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Eisai \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Eisai \/ Not Applicable"},{"orgOrder":0,"company":"Eisai","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"JAPAN","productType":"Small molecule","year":"2021","type":"Not Applicable","leadProduct":"Lenvatinib Mesylate","moa":"VEGFR","graph1":"Oncology","graph2":"Approved","graph3":"Eisai","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Eisai \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Eisai \/ Not Applicable"},{"orgOrder":0,"company":"Eisai","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"JAPAN","productType":"Small molecule","year":"2021","type":"Not Applicable","leadProduct":"Lenvatinib Mesylate","moa":"VEGFR","graph1":"Oncology","graph2":"Phase III","graph3":"Eisai","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Eisai \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"Eisai \/ Not Applicable"},{"orgOrder":0,"company":"Merck & Co","sponsor":"Eisai","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2021","type":"Not Applicable","leadProduct":"Lenvatinib Mesylate","moa":"VEGFR","graph1":"Oncology","graph2":"Approved","graph3":"Merck & Co","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Merck & Co \/ Eisai","highestDevelopmentStatusID":"12","companyTruncated":"Merck & Co \/ Eisai"},{"orgOrder":0,"company":"Eisai","sponsor":"Merck & Co","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"JAPAN","productType":"Small molecule","year":"2021","type":"Not Applicable","leadProduct":"Lenvatinib Mesylate","moa":"VEGFR","graph1":"Oncology","graph2":"Approved","graph3":"Eisai","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Eisai \/ Merck","highestDevelopmentStatusID":"12","companyTruncated":"Eisai \/ Merck"},{"orgOrder":0,"company":"CStone Pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"Lenvatinib Mesylate","moa":"","graph1":"Oncology","graph2":"Phase III","graph3":"CStone Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"CStone Pharmaceuticals \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"CStone Pharmaceuticals \/ Not Applicable"},{"orgOrder":0,"company":"BDR Pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"INDIA","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Lenvatinib Mesylate","moa":"","graph1":"Oncology","graph2":"Approved","graph3":"BDR Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"BDR Pharmaceuticals \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"BDR Pharmaceuticals \/ Not Applicable"}]

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    Lenvatinib Mesylate

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                            01

                            CStone Pharmaceuticals

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                            CStone Pharmaceuticals

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                            Lead Product(s) : Nofazinlimab,Lenvatinib Mesylate

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            CStone Announced the Global Multi-Regional Registration Trial of Anti-PD-1 Antibody Nofazinlimab in Combinatio...

                            Details : CS1003 (nofazinlimab) is a humanized recombinant IgG4 monoclonal antibody targeting human programmed cell death protein 1 (PD-1) being developed in combination with lenvatinib as first-line treatment for patients with advanced hepatocellular carcinoma.

                            Brand Name : CS1003

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            March 18, 2022

                            Lead Product(s) : Nofazinlimab,Lenvatinib Mesylate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Eisai

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                            Eisai

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                            Lead Product(s) : Lenvatinib Mesylate,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Merck & Co

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            LENVIMA® (Lenvatinib) Plus KEYTRUDA® (Pembrolizumab) Approved in Japan for Patients With Unresectable, Advan...

                            Details : MHLW has approved the combination of LENVIMA (lenvatinib) multiple receptor tyrosine kinase inhibitor Plus KEYTRUDA® (pembrolizumab) anti-PD-1 therapy for the treatment of patients with endometrial carcinoma.

                            Brand Name : Lenvima

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 24, 2021

                            Lead Product(s) : Lenvatinib Mesylate,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Merck & Co

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Merck & Co

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                            Lead Product(s) : Lenvatinib Mesylate,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Eisai

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Merck and Eisai Receive Positive EU CHMP Opinions for KEYTRUDA® (Pembrolizumab) Plus LENVIMA® (Lenvatinib) i...

                            Details : KEYTRUDA plus LENVIMA is the first anti-PD-1 and tyrosine kinase inhibitor combination to demonstrate a survival benefit in advanced endometrial carcinoma patients, and the benefit was shown regardless of mismatch repair status.

                            Brand Name : Lenvima

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 15, 2021

                            Lead Product(s) : Lenvatinib Mesylate,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Eisai

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Eisai

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                            Eisai

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                            Lead Product(s) : Lenvatinib Mesylate,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            ADC Therapeutics Announces FDA Approval of ZYNLONTA™ (loncastuximab tesirine-lpyl) in Relapsed or Refractory...

                            Details : In this trial, LENVIMA plus KEYTRUDA showed a statistically significant and clinically meaningful improvement in the primary endpoints of Progression-Free Survival and Overall Survival as well as the secondary endpoint of Objective Response Rate versus c...

                            Brand Name : Lenvima

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            April 23, 2021

                            Lead Product(s) : Lenvatinib Mesylate,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Eisai

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                            Eisai

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                            Lead Product(s) : Lenvatinib Mesylate,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Eisai: EMA Accepts the MAA for Two Additional Indications of Anti Cancer Agent Lenvatinib and Pembrolizumab Co...

                            Details : The application requesting an indication of lenvatinib in combination with pembrolizumab for RCC is based on the results of the pivotal Phase 3 CLEAR study (Study 307/KEYNOTE-581) for the first-line treatment of patients with advanced RCC.

                            Brand Name : Lenvima

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 30, 2021

                            Lead Product(s) : Lenvatinib Mesylate,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Eisai

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                            Eisai

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                            Lead Product(s) : Lenvatinib Mesylate,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Eisai’s Anti-Cancer Agent LENVIMA Receives Orphan Drug Designation

                            Details : The pivotal Phase 3 Study 309/KEYNOTE-775 evaluated LENVIMA in combination with KEYTRUDA® in patients with advanced endometrial cancer, following at least one prior platinum-based regimen in Japan, the United States, Europe and other countries.

                            Brand Name : Lenvima

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 15, 2021

                            Lead Product(s) : Lenvatinib Mesylate,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            BDR Pharmaceuticals

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                            BDR Pharmaceuticals

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                            Lead Product(s) : Lenvatinib Mesylate

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            BDR Pharma Launches Generic Lenvatinib for Cancer Patients in India

                            Details : Bdfoie (lenvatinib mesylate), an oral receptor tyrosine kinase inhibitor, launched in India, for the treatment of differentiated thyroid cancer, advanced liver cancer and advanced kidney cancer.

                            Brand Name : Bdfoie

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 21, 2020

                            Lead Product(s) : Lenvatinib Mesylate

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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