Lead Product(s) : Leriglitazone
Therapeutic Area : Genetic Disease
Study Phase : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : MIN-102 (leriglitazone) is Minoryx’s novel orally bioavailable and selective PPARγ agonist with a potential first-in-class and best-in-class profile for adult male X-linked Adrenoleukodystrophy (X-ALD) patients with cerebral Adrenoleukodystrophy.
Brand Name : MIN-102
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 01, 2023
Lead Product(s) : Leriglitazone
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Leriglitazone
Therapeutic Area : Genetic Disease
Study Phase : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Treatment with leriglitazone demonstrated PPARg engagement in all patients within the target range required for efficacy as assessed by a biomarker (adiponectin).
Brand Name : MIN-102
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 26, 2021
Lead Product(s) : Leriglitazone
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Leriglitazone
Therapeutic Area : Genetic Disease
Study Phase : Phase II/ Phase III
Sponsor : European Investment Bank
Deal Size : $29.0 million
Deal Type : Funding
Details : The EU bank will grant long-term financing to Minoryx to drive the company’s research and development activities in orphan genetic diseases which includes Pivotal Phase 2/3 ADVANCE study, Phase 2 NEXUS study and Phase 2 FRAMES study.
Brand Name : MIN-102
Molecule Type : Small molecule
Upfront Cash : Undisclosed
October 30, 2020
Lead Product(s) : Leriglitazone
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II/ Phase III
Sponsor : European Investment Bank
Deal Size : $29.0 million
Deal Type : Funding
Lead Product(s) : Leriglitazone
Therapeutic Area : Genetic Disease
Study Phase : Phase II/ Phase III
Sponsor : Sperogenix Therapeutics
Deal Size : $78.0 million
Deal Type : Licensing Agreement
Details : Sperogenix will receive exclusive rights to develop and commercialize leriglitazone for the treatment of X-linked adrenoleukodystrophy (X-ALD), a rare life-threatening neurological condition.
Brand Name : MIN-102
Molecule Type : Small molecule
Upfront Cash : Undisclosed
September 23, 2020
Lead Product(s) : Leriglitazone
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II/ Phase III
Sponsor : Sperogenix Therapeutics
Deal Size : $78.0 million
Deal Type : Licensing Agreement
Lead Product(s) : Leriglitazone
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The Phase 2 NEXUS trial aims at evaluating the safety and efficacy of leriglitazone in pediatric patients with early-stage cerebral ALD (cALD), the acute form of X-linked adrenoleukodystrophy (X-ALD).
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 12, 2020
Lead Product(s) : Leriglitazone
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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