Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Certepetide,Calcium Folinate
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lisata Therapeutics Announces Completion of Enrollment in the CENDIFOX Trial
Details : CEND-1 (certepetide) is an Alpha-V integrin inhibitor peptide candidiate which is being evaluated in combination with chemotherapy for the treatment of pancreatic cancer.
Product Name : CEND-1
Product Type : Peptide
Upfront Cash : Inapplicable
December 10, 2024
Lead Product(s) : Certepetide,Calcium Folinate
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Certepetide,Calcium Folinate
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Lisata Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Haystack Oncology and Lisata Therapeutics Start Collaboration to Use MRD™ Tech
Details : Through the collaboration, Lisata will utilize MRD technology to detect ctDNA in a clinical trial evaluating CEND-1 (certepetide) combined with chemotherapy for the treatment of pancreatic cancer.
Product Name : CEND-1
Product Type : Peptide
Upfront Cash : Undisclosed
July 18, 2024
Lead Product(s) : Certepetide,Calcium Folinate
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Lisata Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Cetuximab Beta,Calcium Folinate
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Simcere Zaiming Announce Approval of Cetuximab Beta in China by the NMPA
Details :
Product Name : Enlituo
Product Type : Antibody
Upfront Cash : Inapplicable
June 26, 2024
Lead Product(s) : Cetuximab Beta,Calcium Folinate
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zolbetuximab,Calcium Folinate
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Astellas' VYLOY™ (zolbetuximab) Approved in Japan for Treatment of Gastric Cancer
Details : Astellas' Vyloy (zolbetuximab), a CLDN 18.2 inhibitor has been approved in combination with chemotherapy for HER2-negative, CLDN18.2 positive, unresectable, advanced or recurrent gastric cancer.
Product Name : IMAB362
Product Type : Antibody
Upfront Cash : Inapplicable
March 26, 2024
Lead Product(s) : Zolbetuximab,Calcium Folinate
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Fluorouracil,Calcium Folinate
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Allarity Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Details :
Product Name : Deflexifol
Product Type : Cytotoxic Drug
Upfront Cash : Undisclosed
July 31, 2023
Lead Product(s) : Fluorouracil,Calcium Folinate
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Allarity Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Fluorouracil,Calcium Folinate
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Syneos Health
Deal Size : Undisclosed
Deal Type : Collaboration
FivepHusion Announces Strategic Collaboration with Treehill Partners and Syneos Health
Details :
Product Name : Deflexifol
Product Type : Cytotoxic Drug
Upfront Cash : Undisclosed
May 26, 2023
Lead Product(s) : Fluorouracil,Calcium Folinate
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Syneos Health
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Zolbetuximab,Calcium Folinate
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : IMAB362 (zolbetuximab) is an investigational, first-in-class chimeric IgG1 mAb that targets and binds to CLDN18.2 present on the cancer cell surface of gastric epithelial cells. It induces cancer cell death by activating ADCC and CDC immune system.
Product Name : IMAB362
Product Type : Antibody
Upfront Cash : Inapplicable
January 20, 2023
Lead Product(s) : Zolbetuximab,Calcium Folinate
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zolbetuximab,Calcium Folinate
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : IMAB362 (zolbetuximab) is an investigational first-in-class mAB targeting Claudin 18.2 (CLDN18.2), for first-line treatment of patients with CLDN18.2-positive, HER2-negative, locally advanced unresectable or metastatic gastric or gastroesophageal junctio...
Product Name : IMAB362
Product Type : Antibody
Upfront Cash : Inapplicable
November 17, 2022
Lead Product(s) : Zolbetuximab,Calcium Folinate
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Devimistat,Calcium Folinate
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : CPI-613® (devimistat), is designed to target the mitochondria of cancer cells in order to disrupt their energy production, cutting off the fuel for disease growth.
Product Name : CPI-613
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
June 27, 2022
Lead Product(s) : Devimistat,Calcium Folinate
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Devimistat,Calcium Folinate
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Sudy published in PLOS ONE titled, Evidence for novel, effective approach to targeting carcinoma catabolism exploiting anti-cancer mitochondrial drug, CPI-613 multi-target, tumor-preferential inhibition of mitochondrial TCA cycle by first-in-class drug, ...
Product Name : CPI-613
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
June 16, 2022
Lead Product(s) : Devimistat,Calcium Folinate
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable