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    [{"orgOrder":0,"company":"Levena Biopharma","sponsor":"Navrogen","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"CHINA","productType":"Large molecule","year":"2020","type":"Collaboration","leadProduct":"Antibody drug conjugates","moa":"HIO","graph1":"Oncology","graph2":"Preclinical","graph3":"Levena Biopharma","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Levena Biopharma \/ Navrogen","highestDevelopmentStatusID":"4","companyTruncated":"Levena Biopharma \/ Navrogen"},{"orgOrder":0,"company":"Levena Biopharma","sponsor":"Sichuan Kelun Pharmaceutical","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"A166","moa":"Tubulin","graph1":"Oncology","graph2":"Phase II","graph3":"Levena Biopharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Levena Biopharma \/ Sichuan Kelun-Biotech Biopharmaceutical","highestDevelopmentStatusID":"8","companyTruncated":"Levena Biopharma \/ Sichuan Kelun-Biotech Biopharmaceutical"},{"orgOrder":0,"company":"Levena Biopharma","sponsor":"Sichuan Kelun Pharmaceutical","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"A166","moa":"Tubulin","graph1":"Oncology","graph2":"Phase II","graph3":"Levena Biopharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Spray","sponsorNew":"Levena Biopharma \/ Levena Biopharma","highestDevelopmentStatusID":"8","companyTruncated":"Levena Biopharma \/ Levena Biopharma"},{"orgOrder":0,"company":"Levena Biopharma","sponsor":"Levena Biopharma","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Large molecule","year":"2023","type":"Not Applicable","leadProduct":"TROP2 Antibody-drug Conjugate","moa":"","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Levena Biopharma","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Levena Biopharma \/ Levena Biopharma","highestDevelopmentStatusID":"7","companyTruncated":"Levena Biopharma \/ Levena Biopharma"}]

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                            Levena Biopharma

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                            Lead Product(s) : TROP2 Antibody-drug Conjugate

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Recipient : Shanghai Escugen Biotechnology

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Shanghai Escugen Biotechnology Co., Ltd., a Partner of Levena Biopharma, a Sorrento Company, Releases Positive...

                            Details : ESG401 is composed of a humanized anti-Trop2 IgG1 monoclonal antibody (mAb) conjugated to a topoisomerase I inhibitor SN38 via a proprietary stable covalent linker with a drug antibody ratio (DAR) of 8.

                            Brand Name : ESG401

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            June 05, 2023

                            Lead Product(s) : TROP2 Antibody-drug Conjugate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Recipient : Shanghai Escugen Biotechnology

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Levena Biopharma

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                            Lead Product(s) : A166

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Recipient : Sichuan Kelun Pharmaceutical

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. and Levena Biopharma, a Sorrento Company, are to Present Pos...

                            Details : A166 is an antibody-drug conjugate (ADC) composed of an anti-HER2 antibody conjugated to Duostatin-5, a novel anti-microtubule Auristatin derivative, via a proprietary stable covalent linker.

                            Brand Name : A166

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            June 01, 2022

                            Lead Product(s) : A166

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Recipient : Sichuan Kelun Pharmaceutical

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : A166

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Sichuan Kelun Pharmaceutical

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Levena Biopharma, A Sorrento Company, Announces Positive Clinical Data for Its Out-Licensed A166 Product Candi...

                            Details : A166, a third-generation antibody-drug conjugate with tubulin inhibitor Duo-5 toxin, cleavable linker and site-specific K-Lock conjugation chemistry, demonstrated antitumor activity with meaningful responses in heavily pretreated subjects with HER2-posit...

                            Brand Name : A166

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            May 03, 2022

                            Lead Product(s) : A166

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Sichuan Kelun Pharmaceutical

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : Antibody drug conjugates

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Navrogen

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Navrogen and Levena collaborate to Develop Antibody Drug Conjugates

                            Details : ADCs developed under this collaboration combine Levena’s linker and cytotoxic payload chemistry expertise along with Navrogen’s cancer-targeting antibodies.

                            Brand Name : Undisclosed

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            February 04, 2020

                            Lead Product(s) : Antibody drug conjugates

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Navrogen

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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