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    [{"orgOrder":0,"company":"Orion Biotechnology","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"CANADA","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Levosimendan","moa":"Calcium sensitizer\/K-ATP","graph1":"Neurology","graph2":"Phase III","graph3":"Orion Biotechnology","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Orion Biotechnology \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Orion Biotechnology \/ Inapplicable"},{"orgOrder":0,"company":"Tenax Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Levosimendan","moa":"Calcium sensitizer\/K-ATP","graph1":"Cardiology\/Vascular Diseases","graph2":"Approved FDF","graph3":"Tenax Therapeutics","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Oral","sponsorNew":"Tenax Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Tenax Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Tenax Therapeutics","sponsor":"BVF Partners","pharmaFlowCategory":"D","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Private Placement","leadProduct":"Levosimendan","moa":"Calcium sensitizer\/K-ATP","graph1":"Cardiology\/Vascular Diseases","graph2":"Approved FDF","graph3":"Tenax Therapeutics","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Oral","sponsorNew":"Tenax Therapeutics \/ BVF Partners","highestDevelopmentStatusID":"15","companyTruncated":"Tenax Therapeutics \/ BVF Partners"},{"orgOrder":0,"company":"Tenax Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Levosimendan","moa":"Calcium sensitizer\/K-ATP","graph1":"Cardiology\/Vascular Diseases","graph2":"Approved FDF","graph3":"Tenax Therapeutics","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Oral","sponsorNew":"Tenax Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Tenax Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Tenax Therapeutics","sponsor":"Orion Corporation","pharmaFlowCategory":"D","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Licensing Agreement","leadProduct":"Levosimendan","moa":"Calcium sensitizer\/K-ATP","graph1":"Cardiology\/Vascular Diseases","graph2":"Approved FDF","graph3":"Tenax Therapeutics","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Oral","sponsorNew":"Tenax Therapeutics \/ Orion Corporation","highestDevelopmentStatusID":"15","companyTruncated":"Tenax Therapeutics \/ Orion Corporation"},{"orgOrder":0,"company":"Orion Corporation","sponsor":"Tenax Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"FINLAND","productType":"Other Small Molecule","year":"2020","type":"Licensing Agreement","leadProduct":"Levosimendan","moa":"Calcium sensitizer\/K-ATP","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Phase II","graph3":"Orion Corporation","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Respiratory Diseases","amount2New":0,"dosageForm":"Injection","sponsorNew":"Orion Corporation \/ Tenax Therapeutics","highestDevelopmentStatusID":"8","companyTruncated":"Orion Corporation \/ Tenax Therapeutics"},{"orgOrder":0,"company":"Tenax Therapeutics","sponsor":"H.C. 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                            01

                            Orion Corporation

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                            Lead Product(s) : Levosimendan

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Phase II

                            Sponsor : Tenax Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Tenax Therapeutics Gains North American Rights to Oral Levosimendan through Expanded License Agreement with Or...

                            Details : Amendment to the existing agreement gives Tenax rights to develop and commercialize in the United States and Canada an oral formulation of levosimendan for use with Type 2 pulmonary hypertension in heart failure patients with PH-HFpEF, or other heart rel...

                            Product Name : ODM-109

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            October 15, 2020

                            Lead Product(s) : Levosimendan

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Phase II

                            Sponsor : Tenax Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            02

                            Tenax Therapeutics

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                            Lead Product(s) : Levosimendan

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Tenax Expands Phase 3 for TNX-103 in PH-HFpEF Treatment

                            Details : TNX-103 (levosimendan) is an oral PDE3, small molecule drug candidate, which is currently being evaluated for the treatment of patients with PH-HFpEF.

                            Product Name : TNX-103

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 05, 2025

                            Lead Product(s) : Levosimendan

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Tenax Therapeutics

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                            Lead Product(s) : Levosimendan

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Leerink Partners

                            Deal Size : $25.0 million

                            Deal Type : Private Placement

                            DEALS_DEV arrow-down

                            Tenax Therapeutics Announces $25 Million Private Placement

                            Details : The Company intends to use the net proceeds to advance its ongoing and planned Phase 3 clinical trials, including TNX-103 (oral levosimendan) in patients with PH-HFpEF.

                            Product Name : TNX-103

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            March 05, 2025

                            Lead Product(s) : Levosimendan

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Leerink Partners

                            Deal Size : $25.0 million

                            Deal Type : Private Placement

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                            04

                            Tenax Therapeutics

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                            Lead Product(s) : Levosimendan

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : BVF Partners

                            Deal Size : $100.0 million

                            Deal Type : Private Placement

                            DEALS_DEV arrow-down

                            Tenax Therapeutics Closes $100M Private Placement to Accelerate Levosimendan Phase 3

                            Details : The funding will support the advancement of oral TNX-103 (levosimendan) phase 3 development program for the treatment of Pulmonary Hypertension Due to Heart Failure with Preserved Ejection Fraction.

                            Product Name : TNX-103

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            December 08, 2024

                            Lead Product(s) : Levosimendan

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : BVF Partners

                            Deal Size : $100.0 million

                            Deal Type : Private Placement

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                            05

                            Tenax Therapeutics

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                            Lead Product(s) : Levosimendan

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Phase III

                            Sponsor : Roth Capital Partners

                            Deal Size : $9.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Tenax Therapeutics Announces Pricing of Approximately $9 Million Public Offering

                            Details : The company intends to use the net proceeds for the clinical development of TNX-103 (levosimendan) for the treatment of pulmonary hypertension and heart failure with preserved ejection fraction.

                            Product Name : TNX-103

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            August 02, 2024

                            Lead Product(s) : Levosimendan

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Phase III

                            Sponsor : Roth Capital Partners

                            Deal Size : $9.0 million

                            Deal Type : Public Offering

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                            06

                            Tenax Therapeutics

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                            Lead Product(s) : Levosimendan

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Tenax Therapeutics Enrolls First Patient in Phase 3 LEVEL Study Of TNX-103

                            Details : TNX-103 (levosimendan) is in Phase 3 trials for pulmonary hypertension in heart failure with preserved ejection fraction, acting as a potassium ATP channel activator.

                            Product Name : TNX-103

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            July 02, 2024

                            Lead Product(s) : Levosimendan

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Tenax Therapeutics

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                            Tenax Therapeutics

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                            Lead Product(s) : Levosimendan

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : BVF Partners

                            Deal Size : $100.0 million

                            Deal Type : Private Placement

                            DEALS_DEV arrow-down

                            Tenax Therapeutics Announces Oversubscribed $100 Million Private Placement

                            Details : The Company intends to use the net proceeds from the private placement to complete its ongoing late-stage clinical trial studies with Patients for the treatment of PH-HFpEF.

                            Product Name : TNX-103

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            June 08, 2024

                            Lead Product(s) : Levosimendan

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : BVF Partners

                            Deal Size : $100.0 million

                            Deal Type : Private Placement

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                            08

                            Tenax Therapeutics

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                            Lead Product(s) : Levosimendan

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Orion Corporation

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Tevogen Bio Prepares to Launch Genetic Predisposition Study for TVGN 489 in Long COVID

                            Details : Under the license agreement, Tenax will be developing and commercializing the TNX-103 (levosimendan) for the treatment of pulmonary hypertension with heart failure with preserved ejection fraction.

                            Product Name : TNX-103

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            February 20, 2024

                            Lead Product(s) : Levosimendan

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Orion Corporation

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            09

                            Tenax Therapeutics

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                            Tenax Therapeutics

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                            Lead Product(s) : Levosimendan

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Tenax Therapeutics Announces FDA Clearance of IND for TNX-103 (oral levosimendan) for the Treatment of Pulmona...

                            Details : TNX-103 (levosimendan), is an oral, small molecule, unique potassium ATP channel activator and calcium sensitizer, being developed for Pulmonary Hypertension with Heart Failure with Preserved Ejection Fraction. There are currently no FDA approved treatme...

                            Product Name : TNX-103

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            November 13, 2023

                            Lead Product(s) : Levosimendan

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Tenax Therapeutics

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                            Tenax Therapeutics

                            U.S.A arrow
                            Pharma Live Expo
                            Not Confirmed
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                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Levosimendan

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Tenax Therapeutics Achieves Major Milestone as USPTO Grants Notice of Allowance for U.S. Patent Application Co...

                            Details : TNX-103 (levosimendan), is an oral, small molecule, unique potassium ATP channel activator and calcium sensitizer, being developed for Pulmonary Hypertension with Heart Failure with Preserved Ejection Fraction. There are currently no FDA approved treatme...

                            Product Name : TNX-103

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 31, 2023

                            Lead Product(s) : Levosimendan

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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