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    [{"orgOrder":0,"company":"Biofrontera","sponsor":"Maruho Co, Ltd","pharmaFlowCategory":"D","therapeuticArea":"Dermatology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Licensing Agreement","leadProduct":"Aminolevulinic Acid HCl","moa":"PPIX","graph1":"Dermatology","graph2":"Approved","graph3":"Biofrontera","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Topical Gel","sponsorNew":"Biofrontera \/ Maruho Co, Ltd","highestDevelopmentStatusID":"12","companyTruncated":"Biofrontera \/ Maruho Co, Ltd"},{"orgOrder":0,"company":"Insightec","sponsor":"SonALAsense","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Collaboration","leadProduct":"Aminolevulinic Acid HCl","moa":"DNA","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Insightec","amount2":0,"highestDevelopmentShortName":"Ph 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    Find Clinical Drug Pipeline Developments & Deals for Levulan

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                            01

                            Biofrontera

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                            Biofrontera

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                            Lead Product(s) : Aminolevulinic Acid HCl

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : $4.2 million

                            Deal Type : Private Placement

                            DEALS_DEV arrow-down

                            Biofrontera Inc. Closes a $4.2 Million Senior Secured Convertible Note

                            Details : The proceeds from this financing will primarily support Biofrontera’s commercial and clinical development initiatives including Ameluz (aminolevulinic acid) for superficial basal cell carcinoma.

                            Brand Name : Ameluz

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            November 22, 2024

                            Lead Product(s) : Aminolevulinic Acid HCl

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : $4.2 million

                            Deal Type : Private Placement

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                            02

                            Biofrontera

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                            Lead Product(s) : Aminolevulinic Acid HCl

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Biofrontera Reports Significant Phase 3 Results for Ameluz®-PDT in Basal Cell Carcinoma

                            Details : Ameluz (Aminolevulinic HCl)is a topical gel, being investigated with the BF-RhodoLED® lamp in the treatment of Superficial Basal Cell Carcinoma.

                            Brand Name : Ameluz

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 31, 2024

                            Lead Product(s) : Aminolevulinic Acid HCl

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Biofrontera

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                            Lead Product(s) : Aminolevulinic Acid HCl

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Biofrontera Completes Database Lock in Ameluz® PDT Study for sBCC

                            Details : Ameluz (5-aminolevulinic acid hydrochloride) is a topical gel that acts as a photosensitizing agent during photodynamic therapy. It is used primarily for the treatmentsuperficial basal cell carcinoma.

                            Brand Name : Ameluz

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 14, 2024

                            Lead Product(s) : Aminolevulinic Acid HCl

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Biofrontera

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                            Biofrontera

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                            Lead Product(s) : Aminolevulinic Acid HCl

                            Therapeutic Area : Dermatology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            FDA OKs Triple-Tube Use of Ameluz Gel for Skin Cancer Treatment

                            Details : Ameluz is the only PDT photosensitizer indicated by the FDA for both lesion-directed and field-directed treatment of Actinic Keratosis.

                            Brand Name : Ameluz

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 07, 2024

                            Lead Product(s) : Aminolevulinic Acid HCl

                            Therapeutic Area : Dermatology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Biofrontera

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                            Biofrontera

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                            Lead Product(s) : Aminolevulinic Acid HCl

                            Therapeutic Area : Dermatology

                            Study Phase : Approved

                            Sponsor : Roth Capital Partners

                            Deal Size : $16.0 million

                            Deal Type : Private Placement

                            DEALS_DEV arrow-down

                            Biofrontera Inc. Announces Closing Of Private Placement Of Up To $16.0 Million

                            Details : The Company intends to fund ongoing activities related to expediting the development and approval of additional indications for Ameluz (aminolevulinic acid hydrochloride) to treat actinic keratoses.

                            Brand Name : Ameluz

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            January 23, 2024

                            Lead Product(s) : Aminolevulinic Acid HCl

                            Therapeutic Area : Dermatology

                            Highest Development Status : Approved

                            Sponsor : Roth Capital Partners

                            Deal Size : $16.0 million

                            Deal Type : Private Placement

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                            06

                            SonALAsense

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                            Lead Product(s) : Aminolevulinic Acid HCl

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            SonALAsense Announces Completion of First Cohort in Phase 2 Study of SONALA-001 Sonodynamic Therapy for Recurr...

                            Details : SONALA-001 (aminolevulinic acid) is a porphyrin precursor and optical imaging agent. The mechanism of action of aminolevulinic acid is as a fluorescence contrast activity.

                            Brand Name : SONALA-001

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 08, 2023

                            Lead Product(s) : Aminolevulinic Acid HCl

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Biofrontera

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                            Biofrontera

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                            Lead Product(s) : Aminolevulinic Acid HCl

                            Therapeutic Area : Dermatology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Biofrontera to Launch Phase 3 Clinical Study Evaluating Ameluz®-PDT for the Treatment of Actinic Keratosis on...

                            Details : AMELUZ® (aminolevulinic acid hydrochloride) topical gel, 10%, a porphyrin precursor, in combination with photodynamic therapy using BF-RhodoLED® lamp, is indicated for lesion-directed and field-directed treatment of actinic keratoses.

                            Brand Name : Ameluz

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            November 21, 2022

                            Lead Product(s) : Aminolevulinic Acid HCl

                            Therapeutic Area : Dermatology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Biofrontera

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                            Biofrontera

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                            Lead Product(s) : Aminolevulinic Acid HCl

                            Therapeutic Area : Dermatology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Biofrontera Inc. Announces Notice of Allowance for Nanoemulsion Composition-of-Matter U.S. Patent

                            Details : AMELUZ (aminolevulinic acid hydrochloride) topical gel, 10%, a porphyrin precursor, in combination with photodynamic therapy using BF-RhodoLED® lamp, is indicated for the lesion-directed and field-directed treatment of actinic keratoses of mild-to-moder...

                            Brand Name : Ameluz

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 06, 2022

                            Lead Product(s) : Aminolevulinic Acid HCl

                            Therapeutic Area : Dermatology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Biofrontera

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                            Biofrontera

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                            Lead Product(s) : Aminolevulinic Acid HCl

                            Therapeutic Area : Dermatology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            New Data and Forecasts for the U.S. Skin Cancer Market Strongly Support the Commercial Opportunity for Biofron...

                            Details : Ameluz (Aminolevulinic Acid Hydrochloride) is utilized along with photodynamic therapy (PDT) provided by the Company’s proprietary lamp devices to form Ameluz®-PDT.

                            Brand Name : Ameluz

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            May 24, 2022

                            Lead Product(s) : Aminolevulinic Acid HCl

                            Therapeutic Area : Dermatology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            Biofrontera

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                            Pharma, Lab & Chemical Expo
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                            Biofrontera

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                            Pharma, Lab & Chemical Expo
                            Not Confirmed
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                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Aminolevulinic Acid HCl

                            Therapeutic Area : Dermatology

                            Study Phase : Approved

                            Sponsor : Roth Capital Partners

                            Deal Size : $9.4 million

                            Deal Type : Private Placement

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                            Biofrontera Inc. Announces Closing of $9.4 Million Private Placement

                            Details : The new funds will aid to expand the market presence and strategic position. Together with broadening the product label through three clinical trials running in parallel with licensing partner, this will unravel the enormous market potential Ameluz® has...

                            Brand Name : Ameluz

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            May 19, 2022

                            Lead Product(s) : Aminolevulinic Acid HCl

                            Therapeutic Area : Dermatology

                            Highest Development Status : Approved

                            Sponsor : Roth Capital Partners

                            Deal Size : $9.4 million

                            Deal Type : Private Placement

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