18
ALL18
Lexeo TherapeuticsYear
18
ALL4
20245
20235
20224
2021DEALS // DEV.
18
ALL6
Deals12
DevelopmentsCountry
18
ALL18
U.S.A18
ALL1
D1 Capital Partners12
Inapplicable3
J.P. Morgan1
Longitude Capital1
Sarepta TherapeuticsTherapeutic Area
18
ALL3
Cardiology/Vascular Diseases9
Genetic Disease3
Neurology3
Rare Diseases and DisordersStudy Phase
18
ALL16
Phase I/ Phase II1
IND Enabling1
DiscoveryDeal Type
18
ALL1
Financing12
Inapplicable2
Private Placement1
Public Offering1
Series A Financing1
Series B FinancingProduct Type
18
ALL18
Cell and Gene therapyDosage Form
18
ALL3
Intracisternal Injection3
Intrathecal Infusion11
Intravenous Infusion1
UndisclosedLead Product
18
ALL3
LX10013
LX10049
LX20062
LX20201
LX2021Target
18
ALL3
APOE-2/APOE-39
FXN3
TPP13
UndisclosedLead Product(s) : LX2006
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : J.P. Morgan
Deal Size : $95.0 million
Deal Type : Private Placement
Lexeo Therapeutics Announces Oversubscribed $95.0 Million Equity Financing
Details : Lexeo intends to use proceeds to advance ongoing clinical stage programs, including LX2006, a gene therapy candidate designed to deliver a functional frataxin gene for treating FA cardiomyopathy.
Product Name : LX2006
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
November 03, 2024
Lead Product(s) : LX2006
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : J.P. Morgan
Deal Size : $95.0 million
Deal Type : Private Placement
Lead Product(s) : LX2006
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lexeo Therapeutics Reports Positive Interim Phase 1/2 Data of LX2006 for Friedreich Ataxia
Details : LX2006 is an AAV-based gene therapy candidate & designed to deliver a functional frataxin gene. It is being evaluated for the treatment of friedreich’s ataxia cardiomyopathy.
Product Name : LX2006
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
July 15, 2024
Lead Product(s) : LX2006
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : LX2006
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lexeo Therapeutics Receives FDA Fast Track Designation for LX2006 for Friedreich's Ataxia
Details : LX2006 is an AAV-based gene therapy candidate & designed to deliver a functional frataxin gene. It is being evaluated for the treatment of friedreich’s ataxia cardiomyopathy.
Product Name : LX2006
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
April 16, 2024
Lead Product(s) : LX2006
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : LX2006
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : J.P. Morgan
Deal Size : $95.0 million
Deal Type : Private Placement
Lexeo Therapeutics Announces Closing of Oversubscribed $95.0 Million Equity Financing
Details : Lexeo will use net proceeds to advance clinical programs, including LX2006, a gene therapy candidate aimed at delivering a functional frataxin gene for FA cardiomyopathy.
Product Name : LX2006
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
March 13, 2024
Lead Product(s) : LX2006
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : J.P. Morgan
Deal Size : $95.0 million
Deal Type : Private Placement
Lead Product(s) : LX2020
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : LX2020 is an AAVrh10-based gene therapy candidate designed to intravenously deliver a functional PKP2 gene to cardiac muscle, which is under phase 1/2 clinical development for the treatment of arrhythmogenic cardiomyopathy (ACM) caused by mutations in th...
Product Name : LX2020
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
December 18, 2023
Lead Product(s) : LX2020
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : LX2021
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Discovery
Sponsor : Sarepta Therapeutics
Deal Size : Undisclosed
Deal Type : Financing
Details : In connection with this investment, the companies will explore the development of novel gene therapy candidates, including LX2021 and LX2022 for a range of cardiovascular diseases.
Product Name : LX2021
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
August 28, 2023
Lead Product(s) : LX2021
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Discovery
Sponsor : Sarepta Therapeutics
Deal Size : Undisclosed
Deal Type : Financing
Lead Product(s) : LX2006
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : LX2006 is an AAV-based gene therapy candidate delivered intravenously and designed to target the cardiac manifestations of FA by delivering a functional frataxin gene to promote the expression of the frataxin protein and restore mitochondrial function in...
Product Name : LX2006
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
June 13, 2023
Lead Product(s) : LX2006
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : LX2006
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : J.P. Morgan
Deal Size : $100.0 million
Deal Type : Public Offering
Lexeo Therapeutics Announces Pricing of Initial Public Offering
Details : The proceeds will advance the development of LX2006, LX2020 and LX1001 and will fund the continued development of other programs and cardiac discovery efforts. LX2006 is an AAV-based gene therapy candidate delivered intravenously for the treatment of FA ...
Product Name : LX2006
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
February 11, 2023
Lead Product(s) : LX2006
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : J.P. Morgan
Deal Size : $100.0 million
Deal Type : Public Offering
Lead Product(s) : LX2020
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : LX2020 is designed to intravenously deliver a functional PKP2 gene to cardiac muscle to increase PKP2 protein levels in the cardiac desmosome, a cell structure critical for cell adhesion.
Product Name : LX2020
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
January 08, 2023
Lead Product(s) : LX2020
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : LX2006
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
LEXEO Therapeutics to Present Clinical and Preclinical Data at Upcoming Scientific Conferences
Details : LX2006 (AAVrh.10hFXN) is an AAV-based gene therapy delivered intravenously for the treatment of FA cardiomyopathy and is designed to transfer the FXN gene to myocardial cells and increase frataxin levels in the mitochondria.
Product Name : LX2006
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
October 27, 2022
Lead Product(s) : LX2006
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable