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    [{"orgOrder":0,"company":"LG Chem","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"LC51-0255","moa":"S1P1 receptor","graph1":"Gastroenterology","graph2":"Phase II","graph3":"LG Chem","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Film Coated Tablet","sponsorNew":"LG Chem \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"LG Chem \/ Not Applicable"},{"orgOrder":0,"company":"LG Chem","sponsor":"TransThera Biosciences","pharmaFlowCategory":"D","therapeuticArea":"Hepatology (Liver, Pancreatic, Gall Bladder)","country":"","productType":"Small molecule","year":"2020","type":"Licensing Agreement","leadProduct":"TT-01025","moa":"VAP-1","graph1":"Hepatology (Liver, Pancreatic, Gall Bladder)","graph2":"Preclinical","graph3":"LG 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Chem","highestDevelopmentStatusID":"4","companyTruncated":"LG Chem \/ LG Chem"},{"orgOrder":0,"company":"LG Chem","sponsor":"MaxCyte","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Cell and Gene therapy","year":"2022","type":"Licensing Agreement","leadProduct":"LR19023","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"LG Chem","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"LG Chem \/ LG Chem","highestDevelopmentStatusID":"4","companyTruncated":"LG Chem \/ LG Chem"},{"orgOrder":0,"company":"LG Chem","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Hepatology (Liver, Pancreatic, Gall Bladder)","country":"","productType":"Small molecule","year":"2022","type":"Not Applicable","leadProduct":"LG203003","moa":"DGAT2","graph1":"Hepatology (Liver, Pancreatic, Gall Bladder)","graph2":"Phase I","graph3":"LG 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\/ Innovent Biologics"},{"orgOrder":0,"company":"LG Chem","sponsor":"UNICEF","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Vaccine","year":"2023","type":"Agreement","leadProduct":"Sabin Inactivated Polio Vaccine","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Approved","graph3":"LG Chem","amount2":0.20000000000000001,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Infectious Diseases","amount2New":0.20000000000000001,"dosageForm":"Injectable\/Injection","sponsorNew":"LG Chem \/ UNICEF","highestDevelopmentStatusID":"12","companyTruncated":"LG Chem \/ UNICEF"},{"orgOrder":0,"company":"LG Chem","sponsor":"Rhythm Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Nutrition and Weight Loss","country":"","productType":"Small molecule","year":"2024","type":"Licensing Agreement","leadProduct":"LB54640","moa":"","graph1":"Nutrition and Weight Loss","graph2":"Phase II","graph3":"LG Chem","amount2":0.31,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Nutrition & Weight Loss","amount2New":0.31,"dosageForm":"","sponsorNew":"LG Chem \/ Rhythm Pharmaceuticals","highestDevelopmentStatusID":"8","companyTruncated":"LG Chem \/ Rhythm Pharmaceuticals"},{"orgOrder":0,"company":"LG Chem","sponsor":"Aveo Oncology","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"LB-LR1109","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"LG Chem","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"LG Chem \/ AVEO Oncology","highestDevelopmentStatusID":"6","companyTruncated":"LG Chem \/ AVEO Oncology"},{"orgOrder":0,"company":"LG Chem","sponsor":"Yifan Pharmaceutical","pharmaFlowCategory":"DU","therapeuticArea":"Musculoskeletal","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Hyaluronic Acid","moa":"","graph1":"Technology","graph2":"Phase I\/II","graph3":"LG Chem","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"LG Chem \/ Yifan Pharmaceutical","highestDevelopmentStatusID":"14","companyTruncated":"LG Chem \/ Yifan Pharmaceutical"}]

    Find Clinical Drug Pipeline Developments & Deals by LG Chem

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                            01

                            LG Chem

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                            Lead Product(s) : Hyaluronic Acid

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Approved

                            Sponsor : Yifan Pharmaceutical

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            LG Chem enters Chinese osteoarthritis treatment market

                            Details : Hyruan One (hyaluronic acid) is a small molecule, dihydrofolate reductase inhibitor, given intra-articularly. It is China’s first single-injection osteoarthritis treatment.

                            Brand Name : Hyruan One

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            July 03, 2024

                            Lead Product(s) : Hyaluronic Acid

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Approved

                            Sponsor : Yifan Pharmaceutical

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            LG Chem

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                            Lead Product(s) : LB-LR1109

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Aveo Oncology

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            LG Chem and AVEO Start Phase 1 Anti-Cancer Compound Study

                            Details : LB-LR1109, an anti-cancer investigational drug, works by modulationg LILRB1, it is being investigated in unresectable and metastatic non-small cell lung cancer, renal cell carcinoma, etc.

                            Brand Name : LB-LR1109

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            June 13, 2024

                            Lead Product(s) : LB-LR1109

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Aveo Oncology

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            LG Chem

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                            Lead Product(s) : LB54640

                            Therapeutic Area : Nutrition and Weight Loss

                            Study Phase : Phase II

                            Sponsor : Rhythm Pharmaceuticals

                            Deal Size : $305.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Rhythm Acquires Global Rights To Oral MC4R Agonist LB54640

                            Details : Under the agreement, Rhythm will acquire global rights for LB54640, an investigational oral small molecule MC4R agonist now in Phase 2 trials for patients with acquired hypothalamic obesity.

                            Brand Name : LB54640

                            Molecule Type : Small molecule

                            Upfront Cash : $100.0 million

                            January 04, 2024

                            Lead Product(s) : LB54640

                            Therapeutic Area : Nutrition and Weight Loss

                            Highest Development Status : Phase II

                            Sponsor : Rhythm Pharmaceuticals

                            Deal Size : $305.0 million

                            Deal Type : Licensing Agreement

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                            04

                            LG Chem

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                            Lead Product(s) : Sabin Inactivated Polio Vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved

                            Sponsor : UNICEF

                            Deal Size : $200.0 million

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            LG Chem to Supply UNICEF with $200 Million Worth of Essential Vaccines

                            Details : Under the terms of the agreement, LG Chem will supply UNICEF with its polio vaccine Eupolio and a pentavalent vaccine Eupenta that prevents diphtheria, pertussis, tetanus, hepatitis B and meningitis to solve global public health issues.

                            Brand Name : Eupolio

                            Molecule Type : Vaccine

                            Upfront Cash : Undisclosed

                            March 14, 2023

                            Lead Product(s) : Sabin Inactivated Polio Vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved

                            Sponsor : UNICEF

                            Deal Size : $200.0 million

                            Deal Type : Agreement

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                            05

                            LG Chem

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                            Lead Product(s) : Tigulixostat

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase III

                            Sponsor : Innovent Biologics

                            Deal Size : $95.5 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Innovent and LG Chem Announce Strategic Collaboration for Tigulixostat, a Novel Non-Purine Xanthine Oxidase In...

                            Details : LC350189 (tigulixostat) is a novel xanthine oxidase inhibitor targeting the reduction of uric acid in purine metabolism, by inhibiting the activity of xanthine oxidase.

                            Brand Name : LC350189

                            Molecule Type : Small molecule

                            Upfront Cash : $10.0 million

                            December 14, 2022

                            Lead Product(s) : Tigulixostat

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase III

                            Sponsor : Innovent Biologics

                            Deal Size : $95.5 million

                            Deal Type : Collaboration

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                            06

                            LG Chem

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                            Lead Product(s) : Tivozanib

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Recipient : Aveo Oncology

                            Deal Size : $566.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            LG Chem to Acquire AVEO Oncology for $15.00 Per Share in Cash

                            Details : AVEO will establish LG Chem’s commercial presence in oncology through AVEO’s lead product, FOTIVDA® (tivozanib), which received U.S. FDA approval for the treatment of relapsed or refractory advanced renal cell carcinoma following two or more prior s...

                            Brand Name : Fotivda

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            October 18, 2022

                            Lead Product(s) : Tivozanib

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Recipient : Aveo Oncology

                            Deal Size : $566.0 million

                            Deal Type : Acquisition

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                            07

                            LG Chem

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                            Lead Product(s) : Tigulixostat

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            LG Chem Enters Final Stage of Clinical Development for New Gout Drug

                            Details : Results from US Phase 2 clinical trial—primary end point set at a challenging level confirmed the potential of LC350189 (tigulixostat) as a new gout treatment distinguished from pre-existing drugs, while also demonstrating safety similar to that of the...

                            Brand Name : LC350189

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            August 03, 2022

                            Lead Product(s) : Tigulixostat

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            LG Chem

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                            Lead Product(s) : LG203003

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            LG Chem Announces First Subject Enrolled in Phase 1 Clinical Trial of NASH New Drug

                            Details : LG203003 is second NASH compound is formulated to suppress the accumulation of fat in liver cells by selectively impeding the activation of DGAT2 (diacylglycerol O-acyltransferase 2), a triglyceride synthetase, thus reducing liver cell damage.

                            Brand Name : LG203003

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            July 14, 2022

                            Lead Product(s) : LG203003

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            LG Chem

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                            Lead Product(s) : LR19023

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Recipient : MaxCyte

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            MaxCyte Signs Strategic Platform License with LG Chem to Advance its Allogeneic CAR-T Programs

                            Details : LG Chem is strengthening its anti-cancer sector through advanced construction of cell drug platform technologies. LR19023, the next-generation CAR-T cell treatment, is currently in the pre-clinical stage and under development as a solid cancer therapeuti...

                            Brand Name : LR19023

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            July 12, 2022

                            Lead Product(s) : LR19023

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Recipient : MaxCyte

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            10

                            LG Chem

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                            Lead Product(s) : PD-L1 XT

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Recipient : Avacta Group

                            Deal Size : Undisclosed

                            Deal Type : Expanded Collaboration

                            DEALS_DEV arrow-down

                            LG Chem Renews License Triggering Payment to Avacta

                            Details : Under the terms of the agreement, LG Chem has the exclusive rights to develop and commercialise, on a global basis, Avacta’s Affimer® PD-L1 inhibitor (PD-L1 XT) with Affimer XT™ serum half-life extension for a range of indications.

                            Brand Name : PD-L1 XT

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            June 30, 2022

                            Lead Product(s) : PD-L1 XT

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Recipient : Avacta Group

                            Deal Size : Undisclosed

                            Deal Type : Expanded Collaboration

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