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                          Top Deals by Deal Size (USD bn)

                          01

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : LIB003 (lerodalcibep) is a potential best in class, novel, small binding protein, third-generation PCSK9 inhibitor, which is being evaluated for the treatment and prevention of cardiovascular disease.

                          Brand Name : LIB003

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          March 19, 2024

                          Lead Product(s) : Lerodalcibep

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase III

                          Sponsor : Hasten Biopharmaceutic

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : LIB003 (lerodalcibep) is a novel, third-generation, PCSK9 inhibitor in development to overcome the limitations of current low density lipoprotein-cholesterol (LDL-C) lowering treatments, including statins and ezetimibe, to achieve the lower LDL-C.

                          Brand Name : LIB003

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          November 14, 2023

                          Lead Product(s) : Lerodalcibep

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Under the terms of the agreement, LIB has granted Hasten the exclusive rights to develop and commercialize LIB003 (lerodalcibep), a next-generation, PCSK9 inhibitor, for patients at very high and high-risk of cardiovascular disease, in Greater China.

                          Brand Name : LIB003

                          Molecule Type : Large molecule

                          Upfront Cash : $20.0 million

                          September 12, 2023

                          Lead Product(s) : Lerodalcibep

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Hasten Biopharmaceutic

                          Deal Size : $325.0 million

                          Deal Type : Licensing Agreement

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