Lead Product(s) : Lingdolinurad
Therapeutic Area : Rheumatology
Study Phase : Phase II/ Phase III
Sponsor : China Medical System Holdings Limited
Deal Size : Undisclosed
Deal Type : Collaboration
Atom, CMS Partner on Lingdolinurad for Gout, Hyperuricemia Treatment
Details : The collaboration aims for the commercialization of ABP-671 (lingdolinurad), a novel oral small molecule URAT1 inhibitor for the treatment of chronic gout and hyperuricemia.
Product Name : ABP-671
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
December 03, 2024
Lead Product(s) : Lingdolinurad
Therapeutic Area : Rheumatology
Highest Development Status : Phase II/ Phase III
Sponsor : China Medical System Holdings Limited
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Lingdolinurad
Therapeutic Area : Rheumatology
Study Phase : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Atom Bioscience Enrolling Patients In Global Phase 2b/3 Of Chronic Gout Treatment
Details : The company's primary product, ABP-671 a novel investigational orally administered URAT1 inhibitor, is currently undergoing Phase 2/3 clinical trials with patients for the treatment of chronic gout.
Product Name : ABP-671
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 24, 2024
Lead Product(s) : Lingdolinurad
Therapeutic Area : Rheumatology
Highest Development Status : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Lingdolinurad
Therapeutic Area : Rheumatology
Study Phase : Phase II/ Phase III
Sponsor : Kaitai Capital
Deal Size : $83.0 million
Deal Type : Series D Financing
Details : The financing will be used for completion of global pivotal clinical trials of ABP-671, its unique orally administered URAT1 inhibitor for chronic gout and to advance to clinical stage the company’s innovative pipeline of drugs for inflammatory and met...
Product Name : ABP-671
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
October 16, 2023
Lead Product(s) : Lingdolinurad
Therapeutic Area : Rheumatology
Highest Development Status : Phase II/ Phase III
Sponsor : Kaitai Capital
Deal Size : $83.0 million
Deal Type : Series D Financing
Lead Product(s) : Lingdolinurad
Therapeutic Area : Rheumatology
Study Phase : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Atom Bioscience Doses First Patient in Phase 2b/3 Clinical Trial of a New Treatment for Chronic Gout
Details : ABP-671 is a small molecule inhibitor of the urate transporter 1 (URAT1) protein, which is involved in the reabsorption of uric acid by the kidneys. In gout patients, ABP-671 reduces the reabsorption of uric acid, increasing its excretion in urine.
Product Name : ABP-671
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 10, 2023
Lead Product(s) : Lingdolinurad
Therapeutic Area : Rheumatology
Highest Development Status : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Lingdolinurad
Therapeutic Area : Rheumatology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ABP-671 is a small molecule inhibitor of the urate transporter 1 (URAT1) protein, which is involved in the reabsorption of uric acid by the kidneys. In gout patients, ABP-671 reduces the reabsorption of uric acid, increasing its excretion in urine.
Product Name : ABP-671
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 03, 2023
Lead Product(s) : Lingdolinurad
Therapeutic Area : Rheumatology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Lingdolinurad
Therapeutic Area : Rheumatology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ABP-671 was well tolerated, with the overall incidence of treatment emergent adverse events similar between the ABP-671 treatment cohorts and the placebo cohorts.
Product Name : ABP-671
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 11, 2022
Lead Product(s) : Lingdolinurad
Therapeutic Area : Rheumatology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Lingdolinurad
Therapeutic Area : Rheumatology
Study Phase : Phase II
Sponsor : Xicheng Jinrui Equity Investment Fund
Deal Size : $45.0 million
Deal Type : Series C Financing
Details : Funding will support company’s anticipated global Phase III clinical trial of lead product, ABP-671, for treatment of hyperuricemia and gout, which affects more than 255 million people worldwide.
Product Name : ABP-671
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
May 01, 2022
Lead Product(s) : Lingdolinurad
Therapeutic Area : Rheumatology
Highest Development Status : Phase II
Sponsor : Xicheng Jinrui Equity Investment Fund
Deal Size : $45.0 million
Deal Type : Series C Financing
Lead Product(s) : Lingdolinurad
Therapeutic Area : Rheumatology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Preliminary data suggest Atom’s compound ABP-671, a small molecule inhibitor of the urate transporter (URAT1) protein reduces uric acid levels to prevent gout flare-ups without the adverse side effects of existing treatments.
Product Name : ABP-671
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 21, 2022
Lead Product(s) : Lingdolinurad
Therapeutic Area : Rheumatology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable