Lead Product(s) : Linperlisib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Linperlisib (YY-20394) is a highly selective and potent PI3Kδ inhibitor that has shown a favorable safety profile, encouraging anti-tumor activities and promising PK and pharmaceutical properties as an oral once-a-day agent in late-stage clinical develo...
Brand Name : YY-20394
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 03, 2022
Lead Product(s) : Linperlisib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Linperlisib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : The University of Texas MD Anderson Cancer Center
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The collaborative approach will provide a steady stream of therapeutic candidates, YL-13027, for oncology clinical development, which the MD Anderson team, including David S. Hong, M.D., deputy chair of Investigational Cancer Therapeutics, will investiga...
Brand Name : YY-20394
Molecule Type : Small molecule
Upfront Cash : Undisclosed
January 20, 2022
Lead Product(s) : Linperlisib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : The University of Texas MD Anderson Cancer Center
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Linperlisib
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Yingli Pharma to Present on the Phase 2 Clinical Trial of Linperlisib
Details : Linperlisib, a potent oral PI3Kδ inhibitor, had robust clinical activity with 79.5% ORR in relapsed or refractory Follicular Lymphoma. The safety data from the FL Phase 2 study indicated that linperlisib was generally safe and tolerable with manageable ...
Brand Name : YY-20394
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 11, 2021
Lead Product(s) : Linperlisib
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Linperlisib
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Jiangsu Hengrui Medicine
Deal Size : $20.0 million
Deal Type : Agreement
Details : Yingli Pharma will grant Hengrui Medicine joint development rights and exclusive commercialization rights of PI3kδ inhibitor YY-20394 in Greater China.
Brand Name : YY-20394
Molecule Type : Small molecule
Upfront Cash : Undisclosed
February 08, 2021
Lead Product(s) : Linperlisib
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Jiangsu Hengrui Medicine
Deal Size : $20.0 million
Deal Type : Agreement
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