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                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : Insulin Glargine,Lixisenatide

                          Therapeutic Area : Endocrinology

                          Study Phase : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Details : Soliqua is a combination of insulin glargine, a basal insulin analog, and lixisenatide, a GLP-1 receptor agonist. It is indicated as treatment to improve glycemic control as an adjunct to diet and exercise, in adults with obesity and type 2 diabetes.

                          Brand Name : Soliqua

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          March 27, 2023

                          Lead Product(s) : Insulin Glargine,Lixisenatide

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Sanofi Company Banner

                          02

                          Lead Product(s) : Insulin Glargine,Lixisenatide

                          Therapeutic Area : Endocrinology

                          Study Phase : Undisclosed

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Details : Participants were randomized to switch from their prior insulin to either Soliqua once daily or premixed insulin twice daily, with starting doses determined and adjusted weekly. Any metformin or SGLT-2i treatment was maintained through the study period.

                          Brand Name : Soliqua

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          June 28, 2021

                          Lead Product(s) : Insulin Glargine,Lixisenatide

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Undisclosed

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Sanofi Company Banner