Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : LBP-EC01
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : BARDA
Deal Size : $23.9 million
Deal Type : Funding
Locus Biosciences Receives $23.9M Funding from BARDA for Phase 2 Trial
Details : Net proceeds will support the development of Locus’ CRISPR-enhanced bacteriophage therapy, LBP-EC01, for treating UTIs caused by drug-resistant E. coli based on Phase 2a clinical trial results.
Brand Name : LBP-EC01
Molecule Type : Large molecule
Upfront Cash : Undisclosed
January 23, 2024
Lead Product(s) : LBP-EC01
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : BARDA
Deal Size : $23.9 million
Deal Type : Funding
Lead Product(s) : LBP-EC01,Trimethoprim,Sulfamethoxazole
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : LBP-EC01 is a Locus crPhage® therapy in development for the treatment of urinary tract infections and other infections caused by the pathogen Escherichia coli (E. coli). It is a bacteriophage cocktail engineered with a CRISPR-Cas3 construct targeting th...
Brand Name : LBP-EC01
Molecule Type : Large molecule
Upfront Cash : Not Applicable
September 13, 2022
Lead Product(s) : LBP-EC01,Trimethoprim,Sulfamethoxazole
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : LBP-EC01
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Artis Ventures
Deal Size : $35.0 million
Deal Type : Series B Financing
Locus Biosciences Announces $35 Million Financing
Details : Proceeds from this financing will support the advancement of lead candidate LBP-EC01, a crPhage precision medicine targeting Escherichia coli (E. coli) bacteria causing urinary tract infections (UTIs).
Brand Name : LBP-EC01
Molecule Type : Large molecule
Upfront Cash : Undisclosed
May 18, 2022
Lead Product(s) : LBP-EC01
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Artis Ventures
Deal Size : $35.0 million
Deal Type : Series B Financing
Lead Product(s) : Engineered Bacteriophage
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Discovery Platform
Sponsor : Hercules Capital
Deal Size : $25.0 million
Deal Type : Financing
Locus Biosciences Secures Financing of up to $25 Million from Hercules Capital
Details : Locus is developing two biotherapeutics to address unmet medical needs: precision products to fight deadly infections, including those caused by multi-drug resistant bacteria; and engineered bacteriophage therapies that utilize bacteria resident in the b...
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
October 19, 2021
Lead Product(s) : Engineered Bacteriophage
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Discovery Platform
Sponsor : Hercules Capital
Deal Size : $25.0 million
Deal Type : Financing
Lead Product(s) : LBP-EC01
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : LBP-EC01 is a CRISPR-Cas3-enhanced bacteriophage precision medicine product targeting E. coli bacteria causing urinary tract infections. Phase 1b trial shows safety and tolerability for LBP-EC01 and help support the overall safety profile for Locus' phag...
Brand Name : LBP-EC01
Molecule Type : Large molecule
Upfront Cash : Not Applicable
February 24, 2021
Lead Product(s) : LBP-EC01
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : LBP-EC01
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : BARDA
Deal Size : $144.0 million
Deal Type : Funding
Details : Funding will support Phase 2 and Phase 3 clinical trials and other activities required to seek marketing approval from the U.S. Food and Drug Administration (FDA) for LBP-EC01.
Brand Name : LBP-EC01
Molecule Type : Large molecule
Upfront Cash : $77.0 million
September 30, 2020
Lead Product(s) : LBP-EC01
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : BARDA
Deal Size : $144.0 million
Deal Type : Funding
Lead Product(s) : LBP-EC01
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : It is the world's first controlled clinical trial for a recombinant bacteriophage therapy this trial represents a significant milestone for the field.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 08, 2020
Lead Product(s) : LBP-EC01
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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