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    Find Clinical Drug Pipeline Developments & Deals by Locus Biosciences

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                            01

                            Locus Biosciences

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                            Lead Product(s) : LBP-EC01

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : BARDA

                            Deal Size : $23.9 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Locus Biosciences Receives $23.9M Funding from BARDA for Phase 2 Trial

                            Details : Net proceeds will support the development of Locus’ CRISPR-enhanced bacteriophage therapy, LBP-EC01, for treating UTIs caused by drug-resistant E. coli based on Phase 2a clinical trial results.

                            Brand Name : LBP-EC01

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            January 23, 2024

                            Lead Product(s) : LBP-EC01

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : BARDA

                            Deal Size : $23.9 million

                            Deal Type : Funding

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                            02

                            Locus Biosciences

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                            Lead Product(s) : LBP-EC01,Trimethoprim,Sulfamethoxazole

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Locus Biosciences Announces First Patient Treated in the ELIMINATE Registrational Phase 2/3 Trial of LBP-EC01 ...

                            Details : LBP-EC01 is a Locus crPhage® therapy in development for the treatment of urinary tract infections and other infections caused by the pathogen Escherichia coli (E. coli). It is a bacteriophage cocktail engineered with a CRISPR-Cas3 construct targeting th...

                            Brand Name : LBP-EC01

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            September 13, 2022

                            Lead Product(s) : LBP-EC01,Trimethoprim,Sulfamethoxazole

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Locus Biosciences

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                            Lead Product(s) : LBP-EC01

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Artis Ventures

                            Deal Size : $35.0 million

                            Deal Type : Series B Financing

                            DEALS_DEV arrow-down

                            Locus Biosciences Announces $35 Million Financing

                            Details : Proceeds from this financing will support the advancement of lead candidate LBP-EC01, a crPhage precision medicine targeting Escherichia coli (E. coli) bacteria causing urinary tract infections (UTIs).

                            Brand Name : LBP-EC01

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            May 18, 2022

                            Lead Product(s) : LBP-EC01

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Artis Ventures

                            Deal Size : $35.0 million

                            Deal Type : Series B Financing

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                            04

                            Locus Biosciences

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                            Lead Product(s) : Engineered Bacteriophage

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Discovery Platform

                            Sponsor : Hercules Capital

                            Deal Size : $25.0 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            Locus Biosciences Secures Financing of up to $25 Million from Hercules Capital

                            Details : Locus is developing two biotherapeutics to address unmet medical needs: precision products to fight deadly infections, including those caused by multi-drug resistant bacteria; and engineered bacteriophage therapies that utilize bacteria resident in the b...

                            Brand Name : Undisclosed

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            October 19, 2021

                            Lead Product(s) : Engineered Bacteriophage

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Discovery Platform

                            Sponsor : Hercules Capital

                            Deal Size : $25.0 million

                            Deal Type : Financing

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                            05

                            Locus Biosciences

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                            Lead Product(s) : LBP-EC01

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Locus Biosciences Completes First-Of-Its-Kind Controlled Clinical Trial for CRISPR-Enhanced Bacteriophage Ther...

                            Details : LBP-EC01 is a CRISPR-Cas3-enhanced bacteriophage precision medicine product targeting E. coli bacteria causing urinary tract infections. Phase 1b trial shows safety and tolerability for LBP-EC01 and help support the overall safety profile for Locus' phag...

                            Brand Name : LBP-EC01

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            February 24, 2021

                            Lead Product(s) : LBP-EC01

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Locus Biosciences

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                            Lead Product(s) : LBP-EC01

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : BARDA

                            Deal Size : $144.0 million

                            Deal Type : Funding

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                            Locus Biosciences Signs Contract with BARDA to Advance $144 Million Precision Medicine Program to Develop LBP-...

                            Details : Funding will support Phase 2 and Phase 3 clinical trials and other activities required to seek marketing approval from the U.S. Food and Drug Administration (FDA) for LBP-EC01.

                            Brand Name : LBP-EC01

                            Molecule Type : Large molecule

                            Upfront Cash : $77.0 million

                            September 30, 2020

                            Lead Product(s) : LBP-EC01

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : BARDA

                            Deal Size : $144.0 million

                            Deal Type : Funding

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                            07

                            Locus Biosciences

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                            Lead Product(s) : LBP-EC01

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Locus Biosciences initiates world's first controlled clinical trial for a CRISPR enhanced bacteriophage therap...

                            Details : It is the world's first controlled clinical trial for a recombinant bacteriophage therapy this trial represents a significant milestone for the field.

                            Brand Name : Undisclosed

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            January 08, 2020

                            Lead Product(s) : LBP-EC01

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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