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Find Clinical Drug Pipeline Developments & Deals by Loxo Oncology Inc

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                          Top Deals by Deal Size (USD bn)

                          01

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : The collaboration includes co-development and co-commercialization agreement for Foghorn’s selective BRM oncology program and undisclosed oncology target. The collaboration includes three additional discovery programs using Foghorn’s proprietary Gene...

                          Brand Name : Undisclosed

                          Molecule Type : Small molecule

                          Upfront Cash : $300.0 million

                          December 13, 2021

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Discovery Platform

                          Recipient : Foghorn Therapeutics

                          Deal Size : $380.0 million

                          Deal Type : Collaboration

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                          02

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : First-time data from the Phase I/II LIBRETTO-001 trial of Retevmo (selpercatinib) treatment showed promising antitumour activity and safety in various RET fusion-positive advanced solid tumours. Safety consistent with known profile of Retevmo.

                          Brand Name : Retevmo

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          April 11, 2021

                          Lead Product(s) : Selpercatinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Recipient : Eli Lilly

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : In the 121 efficacy-evaluable BTK-pretreated patients, the ORR was 62%. This deepening of response over time is consistent with other BTK inhibitors and suggests the overall efficacy profile of LOXO-305 will continue to strengthen with additional follow-...

                          Brand Name : LOXO-305

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          December 07, 2020

                          Lead Product(s) : Loxo-305

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Eli Lilly

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : LOXO-305 oral presentations will provide updated data from the ongoing Phase 1/2 BRUIN clinical trial in previously treated chronic lymphocytic leukemia, small lymphocytic lymphoma, mantle cell lymphoma, Waldenström's macroglobulinemia, and other non-Ho...

                          Brand Name : LOXO-305

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          November 05, 2020

                          Lead Product(s) : Loxo-305,Venetoclax,Rituximab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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