Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : LTI-03
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Aileron Announces Positive Data for LTI-03 in Idiopathic Pulmonary Fibrosis
Details : LTI-03, is a novel, synthetic peptide with a dual mechanism targeting alveolar epithelial cell survival as well as inhibition of profibrotic signaling.
Product Name : LTI-03
Product Type : Peptide
Upfront Cash : Inapplicable
November 13, 2024
Lead Product(s) : LTI-03
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : LTI-03
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Aileron Completes Enrollment in Phase 1b Trial of LTI-03 in Pulmonary Fibrosis
Details : LTI-03 is a novel, Caveolin-1-related peptide that addresses both inhibition of pro-fibrotic signaling & survival of critical epithelial cells. It is being developed for idiopathic pulmonary fibrosis.
Product Name : LTI-03
Product Type : Peptide
Upfront Cash : Inapplicable
September 23, 2024
Lead Product(s) : LTI-03
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : LTI-03
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Titan Partners Group
Deal Size : $40.0 million
Deal Type : Public Offering
Aileron Completes $40 Million Underwritten Registered Direct Offering
Details : The proceeds will advance the clinical development of Aileron’s lead candidate, LTI-03, currently in early-stage trials for idiopathic pulmonary fibrosis.
Product Name : LTI-03
Product Type : Peptide
Upfront Cash : Undisclosed
March 05, 2024
Lead Product(s) : LTI-03
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Titan Partners Group
Deal Size : $40.0 million
Deal Type : Public Offering
Lead Product(s) : LTI-03
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Titan Partners Group
Deal Size : $4.6 million
Deal Type : Public Offering
Positive Initial Data Reported from Immutep's Efti Combined with Radiotherapy in Phase II
Details : The net proceeds will be used to advance the development of LTI-03, a peptide representing an important region of the Caveolin 1 (Cav1) protein, for the treatment of idiopathic pulmonary fibrosis.
Product Name : LTI-03
Product Type : Peptide
Upfront Cash : Undisclosed
January 05, 2024
Lead Product(s) : LTI-03
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Titan Partners Group
Deal Size : $4.6 million
Deal Type : Public Offering
Lead Product(s) : LTI-03
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Aileron Therapeutics Reports Positive Data from Phase 1b Trial Of LTI-03 in IPF
Details : LTI-03 is a novel, Caveolin-1-related peptide that addresses both inhibition of pro-fibrotic signaling and survival of critical epithelial cells. Being developed for idiopathic pulmonary fibrosis.
Product Name : LTI-03
Product Type : Peptide
Upfront Cash : Inapplicable
January 05, 2024
Lead Product(s) : LTI-03
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : LTI-03
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Clear Street LLC
Deal Size : $18.0 million
Deal Type : Private Placement
Aileron Therapeutics Announces Acquisition of Lung Therapeutics
Details : Aileron intends to use the proceeds primarily to complete the ongoing Phase 1b clinical study of LTI-03, a Caveolin-1-related peptide in development for the treatment of idiopathic pulmonary fibrosis.
Product Name : LTI-03
Product Type : Peptide
Upfront Cash : Undisclosed
October 31, 2023
Lead Product(s) : LTI-03
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Clear Street LLC
Deal Size : $18.0 million
Deal Type : Private Placement
Lead Product(s) : LTI-03
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Aileron Therapeutics
Deal Size : Undisclosed
Deal Type : Acquisition
Aileron Therapeutics Announces Acquisition of Lung Therapeutics
Details : The acquisition includes multiple clinical stage, orphan pulmonary disease candidates, including LTI-03, a Caveolin-1-related peptide in development for the treatment of idiopathic pulmonary fibrosis (IPF).
Product Name : LTI-03
Product Type : Peptide
Upfront Cash : Undisclosed
October 31, 2023
Lead Product(s) : LTI-03
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Aileron Therapeutics
Deal Size : Undisclosed
Deal Type : Acquisition
Lead Product(s) : LTI-03
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The phase 1a clinical trial assessed ascending doses of LTI-03,, a Caveolin-1-related peptide in healthy normal volunteers. LTI-03 dose levels from 2.5 mg to 10 mg appeared to be safe and well tolerated with no reports of discontinuations or serious adve...
Product Name : LTI-03
Product Type : Peptide
Upfront Cash : Inapplicable
March 22, 2022
Lead Product(s) : LTI-03
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable