Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : LTI-03
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Aileron Completes Enrollment in Phase 1b Trial of LTI-03 in Pulmonary Fibrosis
Details : LTI-03 is a novel, Caveolin-1-related peptide that addresses both inhibition of pro-fibrotic signaling & survival of critical epithelial cells. It is being developed for idiopathic pulmonary fibrosis.
Brand Name : LTI-03
Molecule Type : Peptide
Upfront Cash : Not Applicable
September 23, 2024
Lead Product(s) : LTI-03
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : LTI-03
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Titan Partners Group
Deal Size : $40.0 million
Deal Type : Public Offering
Aileron Completes $40 Million Underwritten Registered Direct Offering
Details : The proceeds will advance the clinical development of Aileron’s lead candidate, LTI-03, currently in early-stage trials for idiopathic pulmonary fibrosis.
Brand Name : LTI-03
Molecule Type : Peptide
Upfront Cash : Undisclosed
May 03, 2024
Lead Product(s) : LTI-03
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Titan Partners Group
Deal Size : $40.0 million
Deal Type : Public Offering
Lead Product(s) : LTI-03
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Titan Partners Group
Deal Size : $4.6 million
Deal Type : Public Offering
Positive Initial Data Reported from Immutep's Efti Combined with Radiotherapy in Phase II
Details : The net proceeds will be used to advance the development of LTI-03, a peptide representing an important region of the Caveolin 1 (Cav1) protein, for the treatment of idiopathic pulmonary fibrosis.
Brand Name : LTI-03
Molecule Type : Peptide
Upfront Cash : Undisclosed
May 01, 2024
Lead Product(s) : LTI-03
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Titan Partners Group
Deal Size : $4.6 million
Deal Type : Public Offering
Lead Product(s) : LTI-03
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Aileron Therapeutics Reports Positive Data from Phase 1b Trial Of LTI-03 in IPF
Details : LTI-03 is a novel, Caveolin-1-related peptide that addresses both inhibition of pro-fibrotic signaling and survival of critical epithelial cells. Being developed for idiopathic pulmonary fibrosis.
Brand Name : LTI-03
Molecule Type : Peptide
Upfront Cash : Not Applicable
May 01, 2024
Lead Product(s) : LTI-03
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : LTI-03
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Aileron Therapeutics
Deal Size : Undisclosed
Deal Type : Acquisition
Aileron Therapeutics Announces Acquisition of Lung Therapeutics
Details : The acquisition includes multiple clinical stage, orphan pulmonary disease candidates, including LTI-03, a Caveolin-1-related peptide in development for the treatment of idiopathic pulmonary fibrosis (IPF).
Brand Name : LTI-03
Molecule Type : Peptide
Upfront Cash : Undisclosed
October 31, 2023
Lead Product(s) : LTI-03
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Aileron Therapeutics
Deal Size : Undisclosed
Deal Type : Acquisition
Lead Product(s) : LTI-03
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Clear Street LLC
Deal Size : $18.0 million
Deal Type : Private Placement
Aileron Therapeutics Announces Acquisition of Lung Therapeutics
Details : Aileron intends to use the proceeds primarily to complete the ongoing Phase 1b clinical study of LTI-03, a Caveolin-1-related peptide in development for the treatment of idiopathic pulmonary fibrosis.
Brand Name : LTI-03
Molecule Type : Peptide
Upfront Cash : Undisclosed
October 31, 2023
Lead Product(s) : LTI-03
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Clear Street LLC
Deal Size : $18.0 million
Deal Type : Private Placement
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