Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Lumateperone Tosylate
Therapeutic Area : Psychiatry/Psychology
Study Phase : Approved FDF
Sponsor : Johnson & Johnson
Deal Size : $14,600.0 million
Deal Type : Acquisition
J&J Acquires Intra-Cellular Therapies to Expand Neuroscience Portfolio
Details : Through the acquisition, J&J adds Intra-Cellular Caplyta (lumateperone tosylate), an approved product to treat schizophrenia, as well as depressive episodes associated with bipolar depression.
Product Name : Caplyta
Product Type : Other Small Molecule
Upfront Cash : $14,600.0 million
January 13, 2025
Lead Product(s) : Lumateperone Tosylate
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Approved FDF
Sponsor : Johnson & Johnson
Deal Size : $14,600.0 million
Deal Type : Acquisition
Lead Product(s) : Lumateperone Tosylate
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Intra-Cellular Files sNDA for CAPLYTA® in Adjunctive Depression Therapy
Details : Caplyta (lumateperone) is an oral, once daily atypical antipsychotic that acts as a 5-HT2A & D2 receptor antagonist. It is being evaluated for the treatment of major depressive disorder.
Product Name : Undisclosed
Product Type : Small molecule
Upfront Cash : Not Applicable
December 03, 2024
Lead Product(s) : Lumateperone Tosylate
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Lumateperone Tosylate
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Intra-Cellular Reports Positive CAPLYTA Results for Schizophrenia Relapse Prevention
Details : Caplyta (lumateperone) is an oral, once daily atypical antipsychotic that acts as a 5-HT2A & D2 receptor antagonist. It is being evaluated for relapse in adult patients with schizophrenia.
Product Name : Caplyta
Product Type : Small molecule
Upfront Cash : Not Applicable
November 05, 2024
Lead Product(s) : Lumateperone Tosylate
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Lumateperone Tosylate
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Intra-Cellular Therapies Reports Positive Phase 3 Results for Lumateperone in Depression
Details : Caplyta (lumateperone) is an oral, once daily atypical antipsychotic that acts as a 5-HT2A & D2 receptor antagonist. It is being evaluated for the treatment of major depressive disorder.
Product Name : Caplyta
Product Type : Small molecule
Upfront Cash : Not Applicable
June 18, 2024
Lead Product(s) : Lumateperone Tosylate
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Lumateperone Tosylate
Therapeutic Area : Psychiatry/Psychology
Study Phase : Approved
Sponsor : J.P. Morgan
Deal Size : $575.0 million
Deal Type : Public Offering
Intra-Cellular Closes $575 Million Public Offering Including Underwriters' Option
Details : The intend to use the net proceeds from this offering to fund commercialization activities of Caplyta (lumateperone), which is indicated for the treatment of schizophrenia.
Product Name : Caplyta
Product Type : Small molecule
Upfront Cash : Undisclosed
April 24, 2024
Lead Product(s) : Lumateperone Tosylate
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Approved
Sponsor : J.P. Morgan
Deal Size : $575.0 million
Deal Type : Public Offering
Lead Product(s) : Lumateperone Tosylate
Therapeutic Area : Psychiatry/Psychology
Study Phase : Approved
Sponsor : J.P. Morgan
Deal Size : $500.0 million
Deal Type : Public Offering
Intra-Cellular Therapies Prices Public Offering of Common Stock
Details : Caplyta (lumateperone) proceeds will support continued commercialization in treating schizophrenia and bipolar depression.
Product Name : Caplyta
Product Type : Small molecule
Upfront Cash : Undisclosed
April 17, 2024
Lead Product(s) : Lumateperone Tosylate
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Approved
Sponsor : J.P. Morgan
Deal Size : $500.0 million
Deal Type : Public Offering
Lead Product(s) : Lumateperone Tosylate
Therapeutic Area : Psychiatry/Psychology
Study Phase : Approved
Sponsor : J.P. Morgan
Deal Size : $500.0 million
Deal Type : Public Offering
Intra-Cellular Therapies Announces Proposed Public Offering of Common Stock
Details : Caplyta (lumateperone) proceeds will support commercialization activities for its use in schizophrenia and bipolar depression treatment.
Product Name : Caplyta
Product Type : Small molecule
Upfront Cash : Undisclosed
April 16, 2024
Lead Product(s) : Lumateperone Tosylate
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Approved
Sponsor : J.P. Morgan
Deal Size : $500.0 million
Deal Type : Public Offering
Lead Product(s) : Lumateperone Tosylate
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Intra-Cellular Announces Positive Phase 3 Results for Lumateperone in Depression
Details : Caplyta (lumateperone) is an oral, once daily atypical antipsychotic that acts as a 5-HT2A & D2 receptor antagonist. It is being evaluated for the treatment of major depressive disorder.
Product Name : Caplyta
Product Type : Small molecule
Upfront Cash : Not Applicable
April 16, 2024
Lead Product(s) : Lumateperone Tosylate
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Lumateperone Tosylate
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Sun Pharma Gets CDSCO Panel Nod to Study Lumateperone Capsules
Details : Lumateperone tosylate capsule has a combination mechanism of antagonist activity at central serotonin 5-HT2A receptors and postsynaptic antagonist activity at central dopamine D2 receptors. It is used for the treatment of Schizophrenia.
Product Name : Caplyta-Generic
Product Type : Small molecule
Upfront Cash : Not Applicable
June 29, 2023
Lead Product(s) : Lumateperone Tosylate
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Lumateperone Tosylate
Therapeutic Area : Psychiatry/Psychology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Caplyta® (lumateperone) has a combination mechanism of antagonist activity at central serotonin 5-HT2A receptors and postsynaptic antagonist activity at central dopamine D2 receptors. It is investigated for the treatment of bipolar I or bipolar II disor...
Product Name : Caplyta
Product Type : Small molecule
Upfront Cash : Not Applicable
May 31, 2023
Lead Product(s) : Lumateperone Tosylate
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable