Lead Product(s) : Lunresertib,Camonsertib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Repare Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Foundation Medicine Partners with Repare for Genomic Profiling and Companion Diagnostic
Details : The collaboration aims to support Repare’s ongoing clinical development of RP-6306 (lunresertib) oral small molecule inhibitor of PKMYT1 alone or with camonsertib for the treatment of neoplasms.
Brand Name : RP-6306
Molecule Type : Small molecule
Upfront Cash : Undisclosed
June 12, 2024
Lead Product(s) : Lunresertib,Camonsertib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Repare Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Lunresertib,Camonsertib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Repare's Lunresertib Gets FDA Fast Track for Platinum-Resistant Ovarian Cancer
Details : FDA granted Fast Track designation to RP-6306 (lunresertib) in combination with RP-3500 (camonsertib) for CCNE1 amplified, or FBXW7 or PPP2R1A-mutated platinum-resistant ovarian cancer.
Brand Name : RP-6306
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 04, 2024
Lead Product(s) : Lunresertib,Camonsertib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Lunresertib,Debio0123
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Debiopharm
Deal Size : Not Applicable
Deal Type : Not Applicable
Repare and Debiopharm Dosed First Patient in Phase 1/1b MYTHIC Trial
Details : RP-6306 (lunresertib), an oral PKMYT1 inhibitor, is being developed in combination with Debio 0123, a selective WEE1 kinase inhibitor, for treating advanced solid tumors.
Brand Name : RP-6306
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 30, 2024
Lead Product(s) : Lunresertib,Debio0123
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Debiopharm
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Debio 0123,Lunresertib
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Debiopharm
Deal Size : Undisclosed
Deal Type : Collaboration
Debiopharm Partners with Repare To Explore PKMYT1 and WEE1 Inhibition
Details : This collaboration will explore synergy between Debio 0123, a selective WEE1 inhibitor, and RP-6306 (lunresertib), a first-in-class small molecule with anticancer activity.
Brand Name : Debio 0123
Molecule Type : Small molecule
Upfront Cash : Undisclosed
January 04, 2024
Lead Product(s) : Debio 0123,Lunresertib
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Debiopharm
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Lunresertib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Canadian Cancer Trials Group
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : RP-6306 (lunresertib) is a PKMYT1 inhibitor currently in Phase 1 clinical development a potential leading ATR inhibitor currently in Phase 1/2 clinical development and partnered with Roche.
Brand Name : RP-6306
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 07, 2023
Lead Product(s) : Lunresertib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Canadian Cancer Trials Group
Deal Size : Not Applicable
Deal Type : Not Applicable
LOOKING FOR A SUPPLIER?