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    [{"orgOrder":0,"company":"Bristol Myers Squibb","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"U.S.A","productType":"Protein","year":"2020","type":"Inapplicable","leadProduct":"Luspatercept","moa":"TGF-beta","graph1":"Hematology","graph2":"Approved FDF","graph3":"Bristol Myers Squibb","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Bristol Myers Squibb \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Bristol Myers Squibb \/ Inapplicable"},{"orgOrder":0,"company":"Acceleron Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"U.S.A","productType":"Protein","year":"2020","type":"Inapplicable","leadProduct":"Luspatercept","moa":"TGF-beta","graph1":"Hematology","graph2":"Approved FDF","graph3":"Acceleron 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Squibb","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Bristol Myers Squibb \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Bristol Myers Squibb \/ Inapplicable"},{"orgOrder":0,"company":"Bristol Myers Squibb","sponsor":"Acceleron Pharma","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Protein","year":"2021","type":"Inapplicable","leadProduct":"Luspatercept","moa":"TGF-beta","graph1":"Genetic Disease","graph2":"Phase II","graph3":"Bristol Myers Squibb","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Bristol Myers Squibb \/ Acceleron Pharma","highestDevelopmentStatusID":"8","companyTruncated":"Bristol Myers Squibb \/ Acceleron Pharma"},{"orgOrder":0,"company":"Bristol Myers Squibb","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Protein","year":"2021","type":"Inapplicable","leadProduct":"Luspatercept","moa":"TGF-beta","graph1":"Genetic Disease","graph2":"Phase II","graph3":"Bristol Myers Squibb","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Injection","sponsorNew":"Bristol Myers Squibb \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Bristol Myers Squibb \/ Inapplicable"}]

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                            01

                            Bristol Myers Squibb

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                            Lead Product(s) : Luspatercept

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bristol Receives Positive CHMP Opinion for Reblozyl in Transfusion-Dependent Anemia

                            Details : Reblozyl (luspatercept) is a first-in-class TGF beta inhibitor, which is being evaluated for the treatment of transfusion-dependent anemia due to low- to intermediate-risk myelodysplastic syndromes.

                            Product Name : Reblozyl

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            February 23, 2024

                            Lead Product(s) : Luspatercept

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Bristol Myers Squibb

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                            Lead Product(s) : Luspatercept

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            EC Expands Bristol Myers Squibb’s Reblozyl® Approval to Anemia in Lower-Risk MDS Adults

                            Details : Reblozyl (luspatercept) is a first-in-class TGF beta inhibitor, which is being evaluated for the treatment of transfusion-dependent anemia due to low- to intermediate-risk myelodysplastic syndromes.

                            Product Name : Reblozyl

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            February 04, 2024

                            Lead Product(s) : Luspatercept

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Bristol Myers Squibb

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                            Lead Product(s) : Luspatercept

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            U.S. FDA Approves Bristol Myers Squibb’s Reblozyl® (luspatercept-aamt) as First-Line Treatment of Anemia in...

                            Details : Reblozyl (luspatercept) is the first and only therapy to demonstrate superiority compared to an erythropoiesis stimulating agent (ESA) in MDS-related anemia based on interim results from pivotal Phase 3 COMMANDS trial, expanding approved population to ES...

                            Product Name : Reblozyl

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            August 28, 2023

                            Lead Product(s) : Luspatercept

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Bristol Myers Squibb

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                            Lead Product(s) : Luspatercept

                            Therapeutic Area : Rare Diseases and Disorders

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bristol Myers Squibb Receives European Commission Approval of Reblozyl® (luspatercept) for Anemia in Adult Pa...

                            Details : Reblozyl (luspatercept-aamt) is a recombinant fusion protein that binds several endogenous TGF-β superfamily ligands, thereby diminishing Smad2/3 signaling thus, improved hematology parameters associated with ineffective erythropoiesis.

                            Product Name : Reblozyl

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            March 03, 2023

                            Lead Product(s) : Luspatercept

                            Therapeutic Area : Rare Diseases and Disorders

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Bristol Myers Squibb

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                            Lead Product(s) : Luspatercept

                            Therapeutic Area : Rare Diseases and Disorders

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bristol Myers Squibb Receives Positive CHMP Opinion for Reblozyl® (luspatercept) for Adult Patients with Anem...

                            Details : Reblozyl (luspatercept-aamt) is a recombinant fusion protein that binds several endogenous TGF-β superfamily ligands, thereby diminishing Smad2/3 signaling thus, improved hematology parameters associated with ineffective erythropoiesis.

                            Product Name : Reblozyl

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            January 27, 2023

                            Lead Product(s) : Luspatercept

                            Therapeutic Area : Rare Diseases and Disorders

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Bristol Myers Squibb

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                            Lead Product(s) : Luspatercept

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            U.S. FDA Accepts for Priority Review Supplemental Biologics License Application and EMA Validates Application ...

                            Details : Reblozyl (luspatercept-aamt) is a recombinant fusion protein that binds several endogenous TGF-β superfamily ligands, thereby diminishing Smad2/3 signaling. It is being investigated for anemia in adults with lower-risk myelodysplastic syndromes.

                            Product Name : Reblozyl

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            January 05, 2023

                            Lead Product(s) : Luspatercept

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Bristol Myers Squibb

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                            Bristol Myers Squibb

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                            Lead Product(s) : Luspatercept

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bristol Myers Squibb Announces Positive Topline Results of Phase 3 COMMANDS Trial

                            Details : Reblozyl (luspatercept-aamt), a first-in-class therapeutic option, promotes late-stage RBC maturation in animal models. Reblozyl is approved in the U.S. for the treatment of anemia in adult patients with beta thalassemia who require regular red blood cel...

                            Product Name : Reblozyl

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            October 31, 2022

                            Lead Product(s) : Luspatercept

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Bristol Myers Squibb

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                            Bristol Myers Squibb

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                            Lead Product(s) : Luspatercept

                            Therapeutic Area : Rare Diseases and Disorders

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bristol Myers Squibb Announces New Prescription Drug User Fee Act Goal Date for Reblozyl® (luspatercept-aamt)...

                            Details : The sBLA was based on safety and efficacy results from the pivotal Phase 2 BEYOND study evaluating Reblozyl, a first-in-class therapeutic option plus best supportive care in adults with NTD beta thalassemia.

                            Product Name : Reblozyl

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            March 25, 2022

                            Lead Product(s) : Luspatercept

                            Therapeutic Area : Rare Diseases and Disorders

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Bristol Myers Squibb

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                            Bristol Myers Squibb

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                            Lead Product(s) : Luspatercept

                            Therapeutic Area : Rare Diseases and Disorders

                            Study Phase : Phase III

                            Sponsor : Acceleron Pharma

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bristol Myers Squibb Withdraws Supplemental Biologics License Application (sBLA) for Reblozyl® (luspatercept-...

                            Details : Reblozyl (luspatercept-aamt) first-in-class therapeutic option, promotes late-stage red blood cell maturation in animal models, is currently approved in the U.S. for treatment of anemia in adult patients with beta thalassemia who require regular red bloo...

                            Product Name : Reblozyl

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            March 06, 2022

                            Lead Product(s) : Luspatercept

                            Therapeutic Area : Rare Diseases and Disorders

                            Highest Development Status : Phase III

                            Sponsor : Acceleron Pharma

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Bristol Myers Squibb

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                            Lead Product(s) : Luspatercept

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase II

                            Sponsor : Acceleron Pharma

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bristol Myers Squibb and Acceleron Present First Results from Phase 2 BEYOND Study of Reblozyl® (luspatercept...

                            Details : Results showed treatment with Reblozyl plus best supportive care improved anemia in 77% of patients compared to placebo. Reblozyl was generally well tolerated and improvements in hemoglobin correlated with improved patient-reported outcomes over a contin...

                            Product Name : Reblozyl

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            November 06, 2021

                            Lead Product(s) : Luspatercept

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase II

                            Sponsor : Acceleron Pharma

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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