Lead Product(s) : Luvadaxistat
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Neurocrine Updates ERUDITE™ Phase 2 Data for Luvadaxistat in Cognitive Impairment
Details : Luvadaxistat (NBI-1065844) is an investigational, oral, selective inhibitor with a high binding affinity to d-amino acid oxidase (DAAO), being investigated for schizophrenia.
Brand Name : NBI-1065844
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 12, 2024
Lead Product(s) : Luvadaxistat
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Luvadaxistat
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Investigational drug luvadaxistat (NBI-1065844/TAK-831) did not meet its primary endpoint in the Phase II INTERACT study in adults with negative symptoms of schizophrenia, as measured by the change from baseline on the PANSS NSFS at Day 84.
Brand Name : NBI-1065844
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 02, 2021
Lead Product(s) : Luvadaxistat
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Luvadaxistat
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Neurocrine Biosciences
Deal Size : $2,015.0 million
Deal Type : Collaboration
Details : Under the terms of the agreement, Takeda granted an exclusive license to Neurocrine Biosciences for seven pipeline programs, including three clinical stage assets for schizophrenia, treatment-resistant depression and anhedonia.
Brand Name : TAK-831
Molecule Type : Small molecule
Upfront Cash : $120.0 million
June 16, 2020
Lead Product(s) : Luvadaxistat
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Neurocrine Biosciences
Deal Size : $2,015.0 million
Deal Type : Collaboration
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