Lead Product(s) : Luveltamab Tazevibulin,Pegfilgrastim
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Boehringer Ingelheim GmbH
Deal Size : Undisclosed
Deal Type : Collaboration
Sutro, Boehringer Partner on Cell-Free Biopharma Manufacturing Scale-Up
Details : The collaboration aims to commercial scale to manufacture Luvelta (luveltamab tazevibulin), Sutro’s Tubulin FRα-targeting ADC designed to treat a broad range of patients with ovarian cancer.
Product Name : Luvelta
Product Type : Antibody-drug Conjugate
Upfront Cash : Undisclosed
January 07, 2025
Lead Product(s) : Luveltamab Tazevibulin,Pegfilgrastim
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Boehringer Ingelheim GmbH
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Luveltamab Tazevibulin,Pegfilgrastim
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Sutro Bio Announces Results from REFRαME-O1 Trial in Platinum-Resistant Ovarian Cancer
Details : STRO-002 (luveltamab tazevibulin), is a best-in-class FolRα-targeting ADC, is being investigated in clinical trials for ovarian cancers in combination with Pegfilgrastim.
Product Name : Luvelta
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
December 10, 2024
Lead Product(s) : Luveltamab Tazevibulin,Pegfilgrastim
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Luveltamab Tazevibulin
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Sutro Biopharma Begins REFRαME-P1 Trial with Luvelta in Pediatric CBF/GLIS AML
Details : Luveltamab tazevibulin, formerly known as STRO-002, is a FR alpha-targeting antibody-drug conjugate (ADC) for Pediatric Patients with CBF/GLIS acute myeloid leukemia.
Product Name : STRO-002
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
November 01, 2024
Lead Product(s) : Luveltamab Tazevibulin
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Luveltamab Tazevibulin
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Sutro Biopharma Starts Phase 2 Trial of Luvelta for Lung Cancer
Details : Luvelta (luveltamab tazevibulin) is an FOLR1 antagonist antibody-drug conjugate, which is being evaluated for the treatment of patients with non-small cell lung cancer.
Product Name : STRO-002
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
August 22, 2024
Lead Product(s) : Luveltamab Tazevibulin
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Luveltamab Tazevibulin,Pegfilgrastim
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Sutro Biopharma
Deal Size : Undisclosed
Deal Type : Partnership
VGXI, Sutro Partner to Support Sutro's Clinical Pipeline
Details : The partnership with Sutro Biopharma to support the clinical production of Luvelta (luveltamab tazevibulin), a novel FRα-targeting antibody-drug conjugate for the treatment of ovarian cancer.
Product Name : Luvelta
Product Type : Antibody-drug Conjugate
Upfront Cash : Undisclosed
June 03, 2024
Lead Product(s) : Luveltamab Tazevibulin,Pegfilgrastim
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Sutro Biopharma
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : Luveltamab Tazevibulin,Pegfilgrastim
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Sutro Biopharma Announces Initiation of Randomized Portion (Part 2) of REFRαME-O1 Trial
Details : STRO-002 (luveltamab tazevibulin), is a best-in-class folate receptor alpha (FolRα)-targeting ADC, is being investigated for ovarian cancers in combination with Pegfilgrastim.
Product Name : STRO-002
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
April 30, 2024
Lead Product(s) : Luveltamab Tazevibulin,Pegfilgrastim
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Luveltamab Tazevibulin,Pegfilgrastim
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : BofA Securities
Deal Size : $75.0 million
Deal Type : Public Offering
Sutro Biopharma Announces Pricing of $75 Million Underwritten Offering
Details : Sutro intends to use the net proceeds of this offering to fund research, clinical, and development of STRO-002 (Luveltamab Tazevibulin) with Neulasta for FOLR1-expressed Ovarian Neoplasms.
Product Name : STRO-002
Product Type : Antibody-drug Conjugate
Upfront Cash : Undisclosed
April 02, 2024
Lead Product(s) : Luveltamab Tazevibulin,Pegfilgrastim
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : BofA Securities
Deal Size : $75.0 million
Deal Type : Public Offering
Lead Product(s) : Luveltamab Tazevibulin
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : STRO-002 (luveltamab tazevibulin), is a best-in-class folate receptor alpha (FolRα)-targeting ADC, is being investigated in a phase 1 clinical trial for ovarian and endometrial cancers. FDA has also granted the fast track designation for STRO-002.
Product Name : STRO-002
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
January 09, 2023
Lead Product(s) : Luveltamab Tazevibulin
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Luveltamab Tazevibulin,Bevacizumab
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Sutro’s proprietary and integrated cell-free protein synthesis platform XpressCF® and site-specific conjugation platform XpressCF+™ led to the discovery of STRO-001 and STRO-002, Sutro’s first two internally-developed ADCs.
Product Name : STRO-002
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
December 21, 2022
Lead Product(s) : Luveltamab Tazevibulin,Bevacizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Luveltamab Tazevibulin
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Sutro has two wholly owned ADCs in the clinic—STRO-002, a folate receptor alpha (FolRα)-targeting ADC, in clinical studies for ovarian and endometrial cancers; and STRO-001, a CD74-targeting ADC, in clinical studies for B-cell malignancies.
Product Name : STRO-002
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
November 03, 2022
Lead Product(s) : Luveltamab Tazevibulin
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable