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    [{"orgOrder":0,"company":"Isotope Technologies Munich","sponsor":"Indigenous Critical Infrastructure Fund Canada","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"GERMANY","productType":"Radiolabelled Compounds","year":"2022","type":"Financing","leadProduct":"177-Lu Edotreotide","moa":"||SST2 receptor","graph1":"Oncology","graph2":"Phase III","graph3":"Isotope Technologies Munich","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Isotope Technologies Munich \/ Indigenous Critical Infrastructure Fund Canada","highestDevelopmentStatusID":"10","companyTruncated":"Isotope Technologies Munich \/ Indigenous Critical Infrastructure Fund Canada"},{"orgOrder":0,"company":"LinPharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Lysine","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Approved FDF","graph3":"LinPharma","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"LinPharma \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"LinPharma \/ Inapplicable"},{"orgOrder":0,"company":"Isotope Technologies Munich","sponsor":"Grand Pharmaceutical Group Limited","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"GERMANY","productType":"Radiolabelled Compounds","year":"2021","type":"Licensing Agreement","leadProduct":"177-Lu Edotreotide","moa":"||SST2 receptor","graph1":"Oncology","graph2":"Phase III","graph3":"Isotope Technologies Munich","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Isotope 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Munich","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Radiolabelled Compounds","year":"2022","type":"Inapplicable","leadProduct":"177-Lu Edotreotide","moa":"||SST2 receptor","graph1":"Oncology","graph2":"Phase III","graph3":"Isotope Technologies Munich","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Isotope Technologies Munich \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Isotope Technologies Munich \/ Inapplicable"},{"orgOrder":0,"company":"Isotope Technologies Munich","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Radiolabelled Compounds","year":"2022","type":"Inapplicable","leadProduct":"177-Lu Edotreotide","moa":"||SST2 receptor","graph1":"Oncology","graph2":"Phase III","graph3":"Isotope Technologies Munich","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Isotope Technologies Munich \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Isotope Technologies Munich \/ Inapplicable"},{"orgOrder":0,"company":"Isotope Technologies Munich","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Radiolabelled Compounds","year":"2022","type":"Inapplicable","leadProduct":"177-Lu Edotreotide","moa":"||SST2 receptor","graph1":"Oncology","graph2":"Phase III","graph3":"Isotope Technologies Munich","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Isotope Technologies Munich \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Isotope Technologies Munich \/ Inapplicable"},{"orgOrder":0,"company":"Isotope Technologies Munich","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Radiolabelled Compounds","year":"2022","type":"Inapplicable","leadProduct":"177-Lu Edotreotide","moa":"||SST2 receptor","graph1":"Oncology","graph2":"Phase III","graph3":"Isotope Technologies Munich","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Isotope Technologies Munich \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Isotope Technologies Munich \/ Inapplicable"},{"orgOrder":0,"company":"Isotope Technologies Munich","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Radiolabelled Compounds","year":"2022","type":"Inapplicable","leadProduct":"177-Lu Edotreotide","moa":"||SST2 receptor","graph1":"Oncology","graph2":"Phase III","graph3":"Isotope Technologies Munich","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Isotope Technologies Munich \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Isotope Technologies Munich \/ Inapplicable"},{"orgOrder":0,"company":"Isotope Technologies Munich","sponsor":"Temasek Life Sciences Laboratory","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"GERMANY","productType":"Radiolabelled Compounds","year":"2023","type":"Financing","leadProduct":"177-Lu Edotreotide","moa":"||SST2 receptor","graph1":"Oncology","graph2":"Phase III","graph3":"Isotope Technologies Munich","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Isotope Technologies Munich \/ Temasek Life Sciences Laboratory","highestDevelopmentStatusID":"10","companyTruncated":"Isotope Technologies Munich \/ Temasek Life Sciences Laboratory"}]

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                            01

                            LinPharma

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                            Lead Product(s) : Lysine

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Lyranda, a Breakthrough Cold Sore Treatment, is Now Available in the U.S.

                            Details : Lyranda (L-lysine) has antiviral effects by blocking the activity of arginine, which promotes the replication of the herpes simplex virus (HSV).

                            Product Name : Lyranda

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            August 28, 2024

                            Lead Product(s) : Lysine

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Isotope Technologies Munich

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                            Lead Product(s) : 177-Lu Edotreotide,Everolimus,Lysine

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Temasek Life Sciences Laboratory

                            Deal Size : $272.7 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            ITM Announces €255m Investment Round, Plans to Advance Radiopharmaceutical Pipeline and to Expand Radioisoto...

                            Details : The net financing will support the development of ITM’s broad Targeted Radionuclide Therapies oncology pipeline and enhance phase III clinical development for its lead pipeline candidate, ITM-11 (n.c.a. 177Lu-edotreotide) in gastroenteropancreatic neur...

                            Product Name : ITM-11

                            Product Type : Radiolabelled Compounds

                            Upfront Cash : Undisclosed

                            May 06, 2023

                            Lead Product(s) : 177-Lu Edotreotide,Everolimus,Lysine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Temasek Life Sciences Laboratory

                            Deal Size : $272.7 million

                            Deal Type : Financing

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                            03

                            Isotope Technologies Munich

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                            Isotope Technologies Munich

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                            Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            ITM Receives FDA Fast Track Designation for Radionuclide Therapy Candidate ITM-11 (n.c.a. 177Lu-edotreotide) i...

                            Details : ITM-11 consists of two components: the medical radioisotope non-carrier-added lutetium-177 (n.c.a. 177Lu) and the targeting molecule edotreotide, a synthetic form of the peptide hormone somatostatin that targets neuroendocrine tumor-specific receptors.

                            Product Name : ITM-11

                            Product Type : Radiolabelled Compounds

                            Upfront Cash : Inapplicable

                            October 27, 2022

                            Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Isotope Technologies Munich

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                            Isotope Technologies Munich

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                            Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            ITM Presents Design of Second Phase III Trial, COMPOSE, with Radiopharmaceutical ITM-11 for the Treatment of N...

                            Details : ITM-11, a targeted radionuclide therapy consisting of high-quality radioisotope, no-carrier-added lutetium-177 combined with somatostatin analog edotreotide is best standard of care for patients with neuroendocrine tumors.

                            Product Name : ITM-11

                            Product Type : Radiolabelled Compounds

                            Upfront Cash : Inapplicable

                            September 03, 2022

                            Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Isotope Technologies Munich

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                            Isotope Technologies Munich

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                            German Wound Congress
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                            Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            ITM to Host Symposium on Actinium-225 Targeted Radionuclide Therapy and to Present Phase III COMPOSE Trial Des...

                            Details : ITM-11 is a Targeted Radionuclide Therapy consisting of the high-quality beta-emitting radioisotope, no-carrier-added lutetium-177 (n.c.a. 177Lu) combined with the tumor-specific targeting molecule edotreotide.

                            Product Name : ITM-11

                            Product Type : Radiolabelled Compounds

                            Upfront Cash : Inapplicable

                            June 15, 2022

                            Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Isotope Technologies Munich

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                            Isotope Technologies Munich

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                            Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            ITM to Present Trial Design of Ongoing Phase III COMPOSE Study in Advanced Neuroendocrine Tumors at ESMO 2022

                            Details : ITM-11 (n.c.a. 177Lu-edotreotide), as first- or second-line treatment compared to best standard of care for patients with well-differentiated aggressive grade 2 and grade 3 somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumors.

                            Product Name : ITM-11

                            Product Type : Radiolabelled Compounds

                            Upfront Cash : Inapplicable

                            June 09, 2022

                            Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Isotope Technologies Munich

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                            Isotope Technologies Munich

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                            Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Indigenous Critical Infrastructure Fund Canada

                            Deal Size : $36.3 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            ITM Receives EUR 33 Million Equity Investment to Advance Precision Oncology Pipeline of Targeted Radiopharmace...

                            Details : The proceeds will be used for the finalization of the late-stage development of the lead candidate ITM-11 (n.c.a. 177Lu-edotreotide), a targeted radiopharmaceutical currently being evaluated in phase III for the treatment of gastroenteropancreatic neuroe...

                            Product Name : ITM-11

                            Product Type : Radiolabelled Compounds

                            Upfront Cash : Undisclosed

                            March 22, 2022

                            Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Indigenous Critical Infrastructure Fund Canada

                            Deal Size : $36.3 million

                            Deal Type : Financing

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                            08

                            Isotope Technologies Munich

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                            Isotope Technologies Munich

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                            Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Grand Pharmaceutical Group Limited

                            Deal Size : $588.4 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            ITM Receives Equity Investment of EUR 25 Million from Strategic Partner Grand Pharma

                            Details : The equity investment follows the licensing agreement between companies which provides GP with rights to develop, manufacture and commercialize ITM’s precision oncology radiopharmaceutical candidates, ITM-11 (n.c.a. 177Lu-edotreotide) and ITM-41 (n.c.a...

                            Product Name : ITM-11

                            Product Type : Radiolabelled Compounds

                            Upfront Cash : Undisclosed

                            February 16, 2022

                            Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Grand Pharmaceutical Group Limited

                            Deal Size : $588.4 million

                            Deal Type : Licensing Agreement

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                            09

                            Isotope Technologies Munich

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                            Isotope Technologies Munich

                            Germany arrow
                            German Wound Congress
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                            Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            ITM Presents Study Design of COMPOSE Phase III Trial with ITM-11 (n.c.a. 177Lu-edotreotide) for Treatment of N...

                            Details : ITM-11 (177Lu-edotreotide), a synthetic form of the peptide hormone somatostatin that targets neuroendocrine tumor-specific receptors demonstrated promising results in its trial for the treatment of hard-to-treat tumors.

                            Product Name : ITM-11

                            Product Type : Radiolabelled Compounds

                            Upfront Cash : Inapplicable

                            January 19, 2022

                            Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Isotope Technologies Munich

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                            Isotope Technologies Munich

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                            Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Grand Pharmaceutical Group Limited

                            Deal Size : $588.4 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            ITM and Grand Pharma Enter into a Commercialization Agreement for Targeted Radiopharmaceuticals in the Greater...

                            Details : Under the terms of the agreement, ITM grants GP an exclusive license for the ITM-11 (n.c.a. 177Lu-edotreotide) and ITM-41 (n.c.a. 177Lu-zoledronate), in the licensed territory and will support the supply of the pharmaceuticals needed for clinical and com...

                            Product Name : ITM-11

                            Product Type : Radiolabelled Compounds

                            Upfront Cash : Undisclosed

                            December 27, 2021

                            Lead Product(s) : 177-Lu Edotreotide,L-Arginine,Lysine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Grand Pharmaceutical Group Limited

                            Deal Size : $588.4 million

                            Deal Type : Licensing Agreement

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