[{"orgOrder":0,"company":"Mabwell","sponsor":"Disc medicine","pharmaFlowCategory":"D","amount":"$412.5 million","upfrontCash":"$10.0 million","newsHeadline":"Mabwell Announces Exclusive Licensing Agreement with Disc Medicine, Inc. for Innovative Drug Candidates of Hematologic Diseases","therapeuticArea":"Hematology","highestDevelopmentStatus":"IND Enabling","country":"","productType":"Large molecule","productStatus":"New Molecular Entity","date":"January 2023","year":"2023","type":"Licensing Agreement","leadProduct":"MWTX-001","moa":"","url1":"","url2":"","graph1":"Hematology","graph2":"IND Enabling","graph3":"Mabwell","amount2":0.40999999999999998,"therapeuticAreaNew":"Hematology","highestDevelopmentStatusNew":"IND Enabling","highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Hematology","productSubType":"","amount2New":0.40999999999999998,"dosageForm":"","sponsorNew":"Mabwell \/ DISC MEDICINE","highestDevelopmentStatusID":"5","companyTruncated":"Mabwell \/ DISC MEDICINE"},{"orgOrder":0,"company":"Mabwell","sponsor":"Disc medicine","pharmaFlowCategory":"D","amount":"$422.5 million","upfrontCash":"$10.0 million","newsHeadline":"Disc Medicine Announces Exclusive Licensing Agreement with Mabwell Therapeutics for Novel Anti-TMPRSS6 Monoclonal Antibodies to Modulate Iron Homeostasis","therapeuticArea":"Genetic Disease","highestDevelopmentStatus":"IND Enabling","country":"","productType":"Large molecule","productStatus":"New Molecular Entity","date":"January 2023","year":"2023","type":"Licensing Agreement","leadProduct":"MWTX-003","moa":"","url1":"","url2":"","graph1":"Genetic Disease","graph2":"IND Enabling","graph3":"Mabwell","amount2":0.41999999999999998,"therapeuticAreaNew":"Genetic Disease","highestDevelopmentStatusNew":"IND Enabling","highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Genetic Disease","productSubType":"","amount2New":0.41999999999999998,"dosageForm":"Injectable\/Injection","sponsorNew":"Mabwell \/ 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                          01

                          Discovery on Target
                          Not Confirmed
                          Discovery on Target
                          Not Confirmed

                          Details : 9MW2821 is China's first, global second Nectin-4 targeted ADC candidate, which is currently being investiated for urothelial carcinoma, in combination with PD-1 inhibitor.

                          Brand Name : 9MW2821

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          August 26, 2024

                          Lead Product(s) : 9MW2821,Toripalimab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Discovery on Target
                          Not Confirmed
                          Discovery on Target
                          Not Confirmed

                          Details : 9MW2821 is China's first, global second Nectin-4 targeted ADC being investiated for recurrent cervical cancer, in combination with PD-1 inhibitor.

                          Brand Name : 9MW2821

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          August 23, 2024

                          Lead Product(s) : 9MW2821,PD-1 Inhibitor

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Discovery on Target
                          Not Confirmed
                          Discovery on Target
                          Not Confirmed

                          Details : 9MW2821 is China's first, global second Nectin-4 targeted ADC being investiated for triple negative breast cancer, in combination with PD-1 inhibitor.

                          Brand Name : 9MW2821

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          August 12, 2024

                          Lead Product(s) : 9MW2821

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Discovery on Target
                          Not Confirmed
                          Discovery on Target
                          Not Confirmed

                          Details : 7MW3711 is a novel antibody-drug conjugate targeting B7-H3, a member of the B7 ligand family & is overexpressed in most cancer type. It is being evaluated for the treatment of small cell lung cancer.

                          Brand Name : 7MW3711

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          July 16, 2024

                          Lead Product(s) : 7MW3711

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Discovery on Target
                          Not Confirmed
                          Discovery on Target
                          Not Confirmed

                          Details : 9MW2821 is China's first, global second Nectin-4 targeted ADC being investiated for triple negative breast cancer, in combination with PD-1 inhibitor.

                          Brand Name : 9MW2821

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          July 15, 2024

                          Lead Product(s) : 9MW2821,Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Discovery on Target
                          Not Confirmed
                          Discovery on Target
                          Not Confirmed

                          Details : 9MW2821 is China's first, global second Nectin-4 targeted ADC being investiated for triple negative breast cancer. It is also being studied in more than 10 different solid tumors.

                          Brand Name : 9MW2821

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          May 13, 2024

                          Lead Product(s) : 9MW2821

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Discovery on Target
                          Not Confirmed
                          Discovery on Target
                          Not Confirmed

                          Details : 9MW2821 is a site-specific conjugated novel Nectin-4-targeting ADC, which is being evaluated for the treatment of advanced, recurrent, or metastatic esophageal squamous cell carcinoma.

                          Brand Name : 9MW2821

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          May 07, 2024

                          Lead Product(s) : 9MW2821

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Discovery on Target
                          Not Confirmed
                          Discovery on Target
                          Not Confirmed

                          Details : Maiweijian (denosumab) is a fully human recombinant anti-RANKL monoclonal antibody, which is approved for the treatment of postmenopausal women with osteoporosis at high risk for fracture.

                          Brand Name : Maiweijian

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          April 08, 2024

                          Lead Product(s) : Denosumab

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Discovery on Target
                          Not Confirmed
                          Discovery on Target
                          Not Confirmed

                          Details : 9MW2821 is a site-specific conjugated novel Nectin-4-targeting ADC, which is being evaluated for the treatment of advanced, recurrent, or metastatic esophageal squamous cell carcinoma.

                          Brand Name : 9MW2821

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          February 27, 2024

                          Lead Product(s) : 9MW2821

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Discovery on Target
                          Not Confirmed
                          Discovery on Target
                          Not Confirmed

                          Details : MW032 (denosumab) is a human monoclonal antibody and a biosimilar candidate to Prolia. It is a RANK ligand inhibitor, which is being evaluated for treament of bone metastases from solid tumors.

                          Brand Name : MW032

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          February 21, 2024

                          Lead Product(s) : Denosumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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