Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Macimorelin
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Aeterna Zentaris
Deal Size : Undisclosed
Deal Type : Merger
Aeterna Zentaris and Ceapro Complete Merger Transaction
Details : The combined company will focus on the development of AEZS-130 (macimorelin), a ghrelin receptor agonist and a small molecule that stimulates the secretion of growth hormone from the pituitary gland.
Product Name : AEZS-130
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
March 06, 2024
Lead Product(s) : Macimorelin
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Aeterna Zentaris
Deal Size : Undisclosed
Deal Type : Merger
Lead Product(s) : Macimorelin
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Aeterna Zentaris
Deal Size : Undisclosed
Deal Type : Merger
Details : The combined company will focus on the development of AEZS-130 (macimorelin), a ghrelin receptor agonist and a small molecule that stimulates the secretion of growth hormone from the pituitary gland.
Product Name : AEZS-130
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
December 14, 2023
Lead Product(s) : Macimorelin
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Aeterna Zentaris
Deal Size : Undisclosed
Deal Type : Merger
Lead Product(s) : Macimorelin
Therapeutic Area : Endocrinology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Macimorelin (Macrilen®; GHRYVELIN™), a ghrelin agonist, is an orally active small molecule that stimulates the secretion of growth hormone from the pituitary gland.
Product Name : Macrilen
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 04, 2023
Lead Product(s) : Macimorelin
Therapeutic Area : Endocrinology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Macimorelin
Therapeutic Area : Endocrinology
Study Phase : Approved FDF
Sponsor : Novo Nordisk
Deal Size : Undisclosed
Deal Type : Termination
Details : Under the Commercial License, Novo Nordisk was granted an exclusive license for the development, manufacturing, registration and commercialization of Macrilen™ (macimorelin) in the U.S. and Canada.
Product Name : Macrilen
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
August 29, 2022
Lead Product(s) : Macimorelin
Therapeutic Area : Endocrinology
Highest Development Status : Approved FDF
Sponsor : Novo Nordisk
Deal Size : Undisclosed
Deal Type : Termination
Lead Product(s) : Macimorelin
Therapeutic Area : Endocrinology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Aeterna Zentaris Announces Positive Results In Dose-Finding Pediatric Study Of Macimorelin
Details : Positive results provide clinical framework to advance the Company’s Pediatric Investigation Plan for macimorelin as a growth hormone deficiency diagnostic.
Product Name : Macrilen
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
June 04, 2020
Lead Product(s) : Macimorelin
Therapeutic Area : Endocrinology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Macimorelin
Therapeutic Area : Endocrinology
Study Phase : Approved FDF
Sponsor : H.C. Wainwright & Co
Deal Size : $12.0 million
Deal Type : Public Offering
Aeterna Zentaris Announces Pricing of $12 Million Public Offering
Details : The Company intends to use the net proceeds of this offering for general corporate purposes, which includes funding of a pediatric clinical trial in the E.U. and U.S. for Macrilen, the investigation of further therapeutic uses of macimorelin.
Product Name : Macrilen
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
January 07, 2020
Lead Product(s) : Macimorelin
Therapeutic Area : Endocrinology
Highest Development Status : Approved FDF
Sponsor : H.C. Wainwright & Co
Deal Size : $12.0 million
Deal Type : Public Offering