Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Empagliflozin
Therapeutic Area : Endocrinology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
New Affordable Diabetes Drug Empagliflozin Launched in India
Details : Empaglyde (empagliflozin) is an SGLT-2 (Sodium-Glucose Co-Transporter-2) inhibitor indicated for use in the treatment of type-2 diabetes mellitus, CKD and chronic heart failure (HF).
Product Name : Empagliflozin-Generic
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 12, 2025
Lead Product(s) : Empagliflozin
Therapeutic Area : Endocrinology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Insulin
Therapeutic Area : Endocrinology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
CDSCO Approves Afrezza® (insulin human) Inhalation Powder in India
Details : Afrezza (human insulin) is a USFDA approved insulin receptor agonist which is indicated for the treatment of type 1 or type 2 diabetes in pediatric patients.
Product Name : Undisclosed
Product Type : Peptide
Upfront Cash : Not Applicable
December 11, 2024
Lead Product(s) : Insulin
Therapeutic Area : Endocrinology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Nintedanib Esylate
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
MannKind Successfully Completes Phase 1 Trial of Nintedanib DPI for Pulmonary Fibrosis
Details : The inhaled therapeutic candidate MNKD-201 (nintedanib) is being evaluated in early-stage clinical trial studies for treating patients suffering from pulmonary fibrotic diseases.
Product Name : MNKD-201
Product Type : Small molecule
Upfront Cash : Not Applicable
November 04, 2024
Lead Product(s) : Nintedanib Esylate
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Clofazimine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
MannKind Begins Phase 3 Trial of Clofazimine Suspension in NTM Lung Disease
Details : MNKD-101 (clofazimine) is active against both slowly growing and rapidly growing mycobacteria and most Gram-positive bacteria in vitro. Being developed for pulmonary nontuberculous mycobacteria.
Product Name : MNKD-101
Product Type : Small molecule
Upfront Cash : Not Applicable
October 30, 2024
Lead Product(s) : Clofazimine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Clofazimine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
MannKind Receives PMDA Clearance for Phase 3 Trial of Clofazimine in NTM Lung Disease
Details : MNKD-101 (clofazimine) is active against both slowly growing and rapidly growing mycobacteria and most Gram-positive bacteria in vitro, being developed for pulmonary nontuberculous mycobacteria.
Product Name : MNKD-101
Product Type : Small molecule
Upfront Cash : Not Applicable
September 18, 2024
Lead Product(s) : Clofazimine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Dihydroergotamine Mesylate
Therapeutic Area : Neurology
Study Phase : Phase I
Sponsor : Pulmatrix
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Pulmatrix Announces Cross License Agreement and Transfer of Laboratory to MannKind
Details : MannKind will grant Pulmatrix a royalty free, exclusive license to use MannKind's Cricket inhalation device for the inhaled delivery of PUR3100, a proprietary formulation of dihydroergotamine.
Product Name : PUR3100
Product Type : Small molecule
Upfront Cash : Undisclosed
May 30, 2024
Lead Product(s) : Dihydroergotamine Mesylate
Therapeutic Area : Neurology
Highest Development Status : Phase I
Sponsor : Pulmatrix
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Clofazimine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
MannKind Receives Fast Track Designation for Clofazimine Inhalation for NTM Lung Disease
Details : MNKD-101 (clofazimine) has antimicrobial and anti-inflammatory effects, active against mycobacteria and Gram-positive bacteria, and is being developed for pulmonary nontuberculous mycobacteria.
Product Name : MNKD-101
Product Type : Small molecule
Upfront Cash : Not Applicable
May 06, 2024
Lead Product(s) : Clofazimine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Nintedanib Esylate
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
MannKind Proceeds with Phase 1 Nintedanib Dpi Study for Pulmonary Fibrotic Diseases
Details : The inhaled therapeutic candidate MNKD-201 (nintedanib) is being evaluated in early-stage clinical trial studies for treating patients suffering from pulmonary fibrotic diseases.
Product Name : MNKD-201
Product Type : Small molecule
Upfront Cash : Not Applicable
April 30, 2024
Lead Product(s) : Nintedanib Esylate
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Clofazimine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
MannKind Announces IND Clearance for Phase 3 Study of Clofazimine Inhalation
Details : MNKD-101 (clofazimine) has antimicrobial and anti-inflammatory effects, active against mycobacteria and Gram-positive bacteria, and is being developed for pulmonary nontuberculous mycobacteria.
Product Name : MNKD-101
Product Type : Small molecule
Upfront Cash : Not Applicable
April 29, 2024
Lead Product(s) : Clofazimine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Technosphere Insulin,Degludec
Therapeutic Area : Endocrinology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
MannKind Completes Enrollment Goal for INHALE-1 Pediatric Diabetes Trial with Afrezza®
Details : Afrezza (technosphere insulin) is a USFDA approved insulin receptor agonist which is being evaluated for the treatment of type 1 or type 2 diabetes in pediatric patients.
Product Name : Afrezza
Product Type : Peptide
Upfront Cash : Not Applicable
February 15, 2024
Lead Product(s) : Technosphere Insulin,Degludec
Therapeutic Area : Endocrinology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable