Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : ML-007,Undisclosed
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
MapLight Announces Phase 1 Results for M1/M4 Agonist in Schizophrenia and Alzheimer’s
Details : ML-007/PAC is an extended-release, fixed-dose combination of M1/M4 agonist, co-formulated with PAC. It is being investigated for schizophrenia and Alzheimer's disease psychosis.
Product Name : Undisclosed
Product Type : Small molecule
Upfront Cash : Not Applicable
December 02, 2024
Lead Product(s) : ML-007,Undisclosed
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ML-007
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Maplight Completes Phase 1 Trial for M1/m4 Agonist in Schizophrenia and Alzheimer's
Details : ML-007C-MA is a combination M1/M4 muscarinic agent. It is under phase 1 clinical development for the treatment of Schizophrenia & Alzheimer's disease psychosis.
Product Name : ML-007
Product Type : Small molecule
Upfront Cash : Not Applicable
January 03, 2024
Lead Product(s) : ML-007
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ML-007C-MA
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Novo Holdings
Deal Size : $225.0 million
Deal Type : Series C Financing
Details : The net funding will advance ML-007C-MA, a novel M1/M4 muscarinic agonist agent combined with a precision matched peripheral muscarinic antagonist, into Phase 2 trials for schizophrenia and Alzheimer's disease psychosis in 2024.
Product Name : ML-007C-MA
Product Type : Small molecule
Upfront Cash : Undisclosed
October 31, 2023
Lead Product(s) : ML-007C-MA
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Novo Holdings
Deal Size : $225.0 million
Deal Type : Series C Financing
Lead Product(s) : ML-007
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ML-007, a novel M1/M4 muscarinic receptor agonist targeting brain circuits shown to be dysfunctional in neurodegenerative and neurocognitive disorders such as schizophrenia, Alzheimer's disease psychosis, and dyskinesias.
Product Name : ML-007
Product Type : Small molecule
Upfront Cash : Not Applicable
August 24, 2023
Lead Product(s) : ML-007
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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