Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Invikafusp Alpha
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Marengo Begins Phase 2 Study of Invikafusp Alfa for PD-1 Resistant Tumors in EU
Details : STAR0602 (invikafusp alfa) is a T-cell activator fusion protein. It is being evaluated for the treatment of patients with advanced anti-PD-1 resistant solid tumors.
Product Name : STAR0602
Product Type : Antibody
Upfront Cash : Inapplicable
December 20, 2024
Lead Product(s) : Invikafusp Alpha
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Ipsen and Marengo Announce Partnership for Precision T Cell Engagers
Details : Research will focus on using Marengo’s TriSTAR platform to reinvigorate and mobilize selective V beta T cells to boost anti-tumor activity in patients with difficult-to-treat cold tumors.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
July 06, 2024
Lead Product(s) : Invikafusp Alpha
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : STAR0602, is a fusion protein that binds to a specific region of TCR Vβ and delivers a unique activation signal on the same T cell, leading to a selective expansion of the targeted T cell subclones. STAR0602 is the first T cell activator generated by Ma...
Product Name : STAR0602
Product Type : Antibody
Upfront Cash : Inapplicable
October 28, 2022
Lead Product(s) : Invikafusp Alpha
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Invikafusp Alpha
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Marengo Therapeutics to Present at Annual J.P. Morgan Health Care Conference
Details : STAR0602, is an antibody fusion molecule that binds and activates a specific Vβ TCR variant T cell subset while also delivering additional signals to the same T cell to further re-program the T cell to enhance anti-tumor activity.
Product Name : STAR0602
Product Type : Antibody
Upfront Cash : Inapplicable
June 01, 2022
Lead Product(s) : Invikafusp Alpha
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Invikafusp Alpha
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Ipsen
Deal Size : $1,592.0 million
Deal Type : Partnership
Details : Marengo will lead the preclinical development efforts and will expense related costs until the submission of an Investigational New Drug (IND) application to the U.S. FDA. Ipsen will assume responsibilities for clinical development and commercialization ...
Product Name : STAR0602
Product Type : Antibody
Upfront Cash : $45.0 million
January 08, 2022
Lead Product(s) : Invikafusp Alpha
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Ipsen
Deal Size : $1,592.0 million
Deal Type : Partnership
Lead Product(s) : Invikafusp Alpha
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Kings College London
Deal Size : Undisclosed
Deal Type : Collaboration
Marengo Therapeutics and King’s College London Advance ImmunoOncology Research Collaboration
Details : STAR0602, is an antibody fusion molecule that binds and activates a specific Vβ TCR variant T cell subset while also delivering additional signals to the same T cell (known as cis-targeting) to further reprogram the T cell, to enhance anti-tumor activit...
Product Name : STAR0602
Product Type : Antibody
Upfront Cash : Undisclosed
August 11, 2021
Lead Product(s) : Invikafusp Alpha
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Kings College London
Deal Size : Undisclosed
Deal Type : Collaboration