Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Invikafusp Alfa
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Marengo Begins Phase 2 Study of Invikafusp Alfa for PD-1 Resistant Tumors in EU
Details : STAR0602 (invikafusp alfa) is a T-cell activator fusion protein. It is being evaluated for the treatment of patients with advanced anti-PD-1 resistant solid tumors.
Product Name : STAR0602
Product Type : Large molecule
Upfront Cash : Not Applicable
December 20, 2024
Lead Product(s) : Invikafusp Alfa
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Ipsen and Marengo Announce Partnership for Precision T Cell Engagers
Details : Research will focus on using Marengo’s TriSTAR platform to reinvigorate and mobilize selective V beta T cells to boost anti-tumor activity in patients with difficult-to-treat cold tumors.
Product Name : Undisclosed
Product Type : Large molecule
Upfront Cash : Undisclosed
June 07, 2024
Lead Product(s) : STAR0602
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : STAR0602, is a fusion protein that binds to a specific region of TCR Vβ and delivers a unique activation signal on the same T cell, leading to a selective expansion of the targeted T cell subclones. STAR0602 is the first T cell activator generated by Ma...
Product Name : STAR0602
Product Type : Large molecule
Upfront Cash : Not Applicable
October 28, 2022
Lead Product(s) : STAR0602
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : STAR002
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Ipsen
Deal Size : $1,592.0 million
Deal Type : Partnership
Details : Marengo will lead the preclinical development efforts and will expense related costs until the submission of an Investigational New Drug (IND) application to the U.S. FDA. Ipsen will assume responsibilities for clinical development and commercialization ...
Product Name : STAR002
Product Type : Large molecule
Upfront Cash : $45.0 million
August 01, 2022
Lead Product(s) : STAR002
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Ipsen
Deal Size : $1,592.0 million
Deal Type : Partnership
Lead Product(s) : STAR0602
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Marengo Therapeutics to Present at Annual J.P. Morgan Health Care Conference
Details : STAR0602, is an antibody fusion molecule that binds and activates a specific Vβ TCR variant T cell subset while also delivering additional signals to the same T cell to further re-program the T cell to enhance anti-tumor activity.
Product Name : STAR0602
Product Type : Large molecule
Upfront Cash : Not Applicable
January 06, 2022
Lead Product(s) : STAR0602
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : STAR0602
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Kings College London
Deal Size : Undisclosed
Deal Type : Collaboration
Marengo Therapeutics and King’s College London Advance ImmunoOncology Research Collaboration
Details : STAR0602, is an antibody fusion molecule that binds and activates a specific Vβ TCR variant T cell subset while also delivering additional signals to the same T cell (known as cis-targeting) to further reprogram the T cell, to enhance anti-tumor activit...
Product Name : STAR0602
Product Type : Large molecule
Upfront Cash : Undisclosed
November 08, 2021
Lead Product(s) : STAR0602
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Kings College London
Deal Size : Undisclosed
Deal Type : Collaboration