[{"orgOrder":0,"company":"Marengo Therapeutics","sponsor":"Kings College London","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2021","type":"Collaboration","leadProduct":"STAR0602","moa":"TCR-V beta","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Marengo Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Dosage Strength\/Form","sponsorNew":"Marengo Therapeutics \/ Kings College London","highestDevelopmentStatusID":"7","companyTruncated":"Marengo Therapeutics \/ Kings College London"},{"orgOrder":0,"company":"Marengo Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"STAR0602","moa":"TCR-V beta","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Marengo Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Marengo Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"7","companyTruncated":"Marengo Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Marengo Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"STAR0602","moa":"TCR-V beta","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Marengo Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Marengo Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"7","companyTruncated":"Marengo Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Marengo Therapeutics","sponsor":"Ipsen","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2022","type":"Partnership","leadProduct":"STAR002","moa":"TCR-V beta","graph1":"Oncology","graph2":"Preclinical","graph3":"Marengo Therapeutics","amount2":1.5900000000000001,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":1.5900000000000001,"dosageForm":"","sponsorNew":"Marengo Therapeutics \/ Ipsen","highestDevelopmentStatusID":"4","companyTruncated":"Marengo Therapeutics \/ Ipsen"},{"orgOrder":0,"company":"Marengo Therapeutics","sponsor":"Ipsen","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2024","type":"Partnership","leadProduct":"T Cell Engager","moa":"","graph1":"Oncology","graph2":"Discovery","graph3":"Marengo Therapeutics","amount2":1.2,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Oncology","amount2New":1.2,"dosageForm":"","sponsorNew":"Marengo Therapeutics \/ Ipsen","highestDevelopmentStatusID":"2","companyTruncated":"Marengo Therapeutics \/ Ipsen"},{"orgOrder":0,"company":"Marengo Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"Invikafusp Alfa","moa":"","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Marengo Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Marengo Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"7","companyTruncated":"Marengo Therapeutics \/ Not Applicable"}]

Find Clinical Drug Pipeline Developments & Deals by Marengo Therapeutics

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                          Top Deals by Deal Size (USD bn)

                          01

                          Organic Process R&D
                          Not Confirmed
                          Organic Process R&D
                          Not Confirmed

                          Details : STAR0602 (invikafusp alfa) is a T-cell activator fusion protein. It is being evaluated for the treatment of patients with advanced anti-PD-1 resistant solid tumors.

                          Product Name : STAR0602

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          December 20, 2024

                          Lead Product(s) : Invikafusp Alfa

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Organic Process R&D
                          Not Confirmed
                          Organic Process R&D
                          Not Confirmed

                          Details : Research will focus on using Marengo’s TriSTAR platform to reinvigorate and mobilize selective V beta T cells to boost anti-tumor activity in patients with difficult-to-treat cold tumors.

                          Product Name : Undisclosed

                          Product Type : Large molecule

                          Upfront Cash : Undisclosed

                          June 07, 2024

                          Lead Product(s) : T Cell Engager

                          Therapeutic Area : Oncology

                          Highest Development Status : Discovery

                          Sponsor : Ipsen

                          Deal Size : $1,200.0 million

                          Deal Type : Partnership

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                          03

                          Organic Process R&D
                          Not Confirmed
                          Organic Process R&D
                          Not Confirmed

                          Details : STAR0602, is a fusion protein that binds to a specific region of TCR Vβ and delivers a unique activation signal on the same T cell, leading to a selective expansion of the targeted T cell subclones. STAR0602 is the first T cell activator generated by Ma...

                          Product Name : STAR0602

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          October 28, 2022

                          Lead Product(s) : STAR0602

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Organic Process R&D
                          Not Confirmed
                          Organic Process R&D
                          Not Confirmed

                          Details : Marengo will lead the preclinical development efforts and will expense related costs until the submission of an Investigational New Drug (IND) application to the U.S. FDA. Ipsen will assume responsibilities for clinical development and commercialization ...

                          Product Name : STAR002

                          Product Type : Large molecule

                          Upfront Cash : $45.0 million

                          August 01, 2022

                          Lead Product(s) : STAR002

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Ipsen

                          Deal Size : $1,592.0 million

                          Deal Type : Partnership

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                          05

                          Organic Process R&D
                          Not Confirmed
                          Organic Process R&D
                          Not Confirmed

                          Details : STAR0602, is an antibody fusion molecule that binds and activates a specific Vβ TCR variant T cell subset while also delivering additional signals to the same T cell to further re-program the T cell to enhance anti-tumor activity.

                          Product Name : STAR0602

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          January 06, 2022

                          Lead Product(s) : STAR0602

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Organic Process R&D
                          Not Confirmed
                          Organic Process R&D
                          Not Confirmed

                          Details : STAR0602, is an antibody fusion molecule that binds and activates a specific Vβ TCR variant T cell subset while also delivering additional signals to the same T cell (known as cis-targeting) to further reprogram the T cell, to enhance anti-tumor activit...

                          Product Name : STAR0602

                          Product Type : Large molecule

                          Upfront Cash : Undisclosed

                          November 08, 2021

                          Lead Product(s) : STAR0602

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Kings College London

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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