Lead Product(s) : Margetuximab
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : TerSera Therapeutics
Deal Size : $75.0 million
Deal Type : Acquisition
MacroGenics Enters into Agreement with TerSera Therapeutics for The Sale of MARGENZA®
Details : Under the agreement, TerSera will acquire global rights to Margenza (margetuximab) from MacroGenics. It is indicated for the treatment of HER2-positive breast cancer.
Product Name : Margenza
Product Type : Antibody
Upfront Cash : Undisclosed
October 22, 2024
Lead Product(s) : Margetuximab
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : TerSera Therapeutics
Deal Size : $75.0 million
Deal Type : Acquisition
Lead Product(s) : Margetuximab,Capecitabine
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : MARGENZA (margetuximab-cmkb) is the first HER2-targeted therapy to have improved progression-free survival (PFS) versus Herceptin® (trastuzumab), both combined with chemotherapy, in a head-to-head Phase 3 clinical trial.
Product Name : Margenza
Product Type : Antibody
Upfront Cash : Inapplicable
December 16, 2020
Lead Product(s) : Margetuximab,Capecitabine
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Margetuximab,MGD013
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
MacroGenics Announces Lancet Oncology Publication of Margetuximab Data in Gastric Cancer
Details : Lancet Oncology has published results from a Phase 2 study of margetuximab plus pembrolizumab as a chemotherapy-free regimen for patients with advanced HER2-positive gastroesophageal adenocarcinoma (GEA) who have previously been treated with chemotherapy...
Product Name : Margenza
Product Type : Antibody
Upfront Cash : Inapplicable
September 07, 2020
Lead Product(s) : Margetuximab,MGD013
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Margetuximab,Capecitabine
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details :
Product Name : MGAH22
Product Type : Antibody
Upfront Cash : Inapplicable
June 10, 2020
Lead Product(s) : Margetuximab,Capecitabine
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Margetuximab
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
MacroGenics Provides Update on FDA Review of Margetuximab for HER2-Positive Metastatic Breast Cancer
Details : FDA notified the Company that it is no longer planning to hold an Oncologic Drugs Advisory Committee (ODAC) meeting to discuss the Biologics License Application (BLA) for margetuximab.
Product Name : Margenza
Product Type : Antibody
Upfront Cash : Inapplicable
May 28, 2020
Lead Product(s) : Margetuximab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Margetuximab,INCMGA00012
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
MacroGenics Announces Margetuximab Granted Orphan Drug Designation in the U.S. for Gastric Cancer
Details : Margetuximab is currently being evaluated in the Phase 2/3 MAHOGANY clinical trial in combination with checkpoint inhibition, with/without chemotherapy, as a first-line treatment for patients with HER2-positive gastric cancer or gastroesophageal junction...
Product Name : Margenza
Product Type : Antibody
Upfront Cash : Inapplicable
May 06, 2020
Lead Product(s) : Margetuximab,INCMGA00012
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable