Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Nemolizumab
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Chugai Pharmaceutical
Deal Size : Not Applicable
Deal Type : Not Applicable
Maruho Launches Mitchga SC Injection for Pruritus in Japan
Details : Mitchga (nemolizumab) is an anti-IL-31 receptor A humanized monoclonal antibody, which is approved for the treatment of atopic dermatitis and prurigo nodularis.
Product Name : Mitchga
Product Type : Large molecule
Upfront Cash : Not Applicable
June 12, 2024
Lead Product(s) : Nemolizumab
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Chugai Pharmaceutical
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Nemolizumab
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Chugai Pharmaceutical
Deal Size : Not Applicable
Deal Type : Not Applicable
Mitchga Approved for Itching in Pediatric Atopic Dermatitis and Prurigo Nodularis
Details : Mitchga (nemolizumab) is an anti-IL-31 receptor A humanized monoclonal antibody, which is approved for the treatment of atopic dermatitis and prurigo nodularis.
Product Name : Mitchga
Product Type : Large molecule
Upfront Cash : Not Applicable
March 26, 2024
Lead Product(s) : Nemolizumab
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Chugai Pharmaceutical
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : B244
Therapeutic Area : Dermatology
Study Phase : Phase II
Recipient : AOBiome Therapeutics
Deal Size : Undisclosed
Deal Type : Licensing Agreement
AOB Pharma Enters License Agreement for Topical Biologic B244 in Japan
Details : The agreement aims to develop AOB's topical biologic B244, preparing for global Phase 3 trials, a therapeutic for dermatological conditions like Atopic Dermatitis and pruritus.
Product Name : B244
Product Type : Large molecule
Upfront Cash : Undisclosed
January 05, 2024
Lead Product(s) : B244
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Recipient : AOBiome Therapeutics
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : EVO756
Therapeutic Area : Immunology
Study Phase : Preclinical
Recipient : Evommune
Deal Size : $60.0 million
Deal Type : Collaboration
Details : The collaboration aims to develop and commercialize EVO756 in Japan. Evommune’s MRGPRX2 antagonist, is an investigational therapy with the potential to be a first-in-class oral treatment for a variety of mast cell mediated disease.
Product Name : EVO756
Product Type : Small molecule
Upfront Cash : Undisclosed
September 27, 2023
Lead Product(s) : EVO756
Therapeutic Area : Immunology
Highest Development Status : Preclinical
Recipient : Evommune
Deal Size : $60.0 million
Deal Type : Collaboration
Lead Product(s) : Nemolizumab
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Chugai Pharmaceutical
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Mitchga (Nemolizumab) is the first antibody drug targeting IL-31 receptor A, for the treatment of itching associated with atopic dermatitis (only when existing treatment is insufficiently effective).
Product Name : Mitchga
Product Type : Large molecule
Upfront Cash : Not Applicable
August 08, 2022
Lead Product(s) : Nemolizumab
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Chugai Pharmaceutical
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BX005
Therapeutic Area : Dermatology
Study Phase : Phase I/ Phase II
Recipient : BiomX
Deal Size : Not Applicable
Deal Type : Not Applicable
IND Accepted to Conduct Clinical Testing of BX005 for the Treatment of Atopic Dermatitis
Details : BX005 is currently in the final stages of GMP production. The Company continues to expect the first data readout from its Phase 1/2 proof-of-concept trial evaluating the safety and efficacy.
Product Name : BX005
Product Type : Large molecule
Upfront Cash : Not Applicable
May 11, 2022
Lead Product(s) : BX005
Therapeutic Area : Dermatology
Highest Development Status : Phase I/ Phase II
Recipient : BiomX
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Ruxolitinib Phosphate
Therapeutic Area : Dermatology
Study Phase : Approved
Recipient : Incyte Corporation
Deal Size : Undisclosed
Deal Type : Agreement
Incyte and Maruho Announce Strategic Alliance Agreement for Ruxolitinib Cream in Japan
Details : Maruho will receive the rights to develop, manufacture and exclusively commercialize ruxolitinib cream, and other potential future topical formulations of ruxolitinib, in autoimmune and inflammatory dermatologic diseases, including vitiligo and atopic de...
Product Name : Opzelura
Product Type : Small molecule
Upfront Cash : Undisclosed
April 28, 2022
Lead Product(s) : Ruxolitinib Phosphate
Therapeutic Area : Dermatology
Highest Development Status : Approved
Recipient : Incyte Corporation
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Nemolizumab
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Chugai Pharmaceutical
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The approval of Mitchga, the first antibody-drug targeting interleukin-31, is based on the results from a Japanese phase III clinical study in patients with moderate to severe AD who are older than 13 years old and are tolerant to existing treatments.
Product Name : Mitchga
Product Type : Large molecule
Upfront Cash : Not Applicable
March 28, 2022
Lead Product(s) : Nemolizumab
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Chugai Pharmaceutical
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Glycopyrronium Tosylate
Therapeutic Area : Dermatology
Study Phase : Approved
Recipient : Journey Medical Corporation
Deal Size : $10.0 million
Deal Type : Agreement
Details : QBREXZA (Rapifort® Wipes 2.5%), is a topical product approved by the U.S. Food and Drug Administration for treatment of primary axillary hyperhidrosis in adult and pediatric populations (ages nine-years and older) and is self-administered by patients.
Product Name : Rapifort Wipes
Product Type : Small molecule
Upfront Cash : Undisclosed
February 11, 2022
Lead Product(s) : Glycopyrronium Tosylate
Therapeutic Area : Dermatology
Highest Development Status : Approved
Recipient : Journey Medical Corporation
Deal Size : $10.0 million
Deal Type : Agreement
Lead Product(s) : BX005
Therapeutic Area : Dermatology
Study Phase : Preclinical
Recipient : BiomX
Deal Size : Undisclosed
Deal Type : Agreement
BiomX Announces Agreement with Maruho Co., Ltd. for Atopic Dermatitis Product Candidate BX005
Details : Maruho also entered into a binding agreement for an equity investment in BiomX of $3 million at a premium to the market share price, intended primarily to support the Phase 1/2 study of atopic dermatitis product candidate, BX005, in Japan.
Product Name : BX005
Product Type : Large molecule
Upfront Cash : Undisclosed
October 13, 2021
Lead Product(s) : BX005
Therapeutic Area : Dermatology
Highest Development Status : Preclinical
Recipient : BiomX
Deal Size : Undisclosed
Deal Type : Agreement