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    Find Clinical Drug Pipeline Developments & Deals by Mateon Therapeutics

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                            01

                            Mateon Therapeutics

                            U.S.A arrow
                            Medlab Asia & Asia Health
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                            Mateon Therapeutics

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                            Lead Product(s) : Trabedersen

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Recipient : Oncotelic Therapeutics

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Oncotelic Presenting Data for OT101 Against Pancreatic Cancer (PDAC) at the SITC 37th Annual Meeting

                            Details : Anti-viral activity OT-101 (trabedersen), in an in vitro antiviral testing which has a 50% effective concentration of 7.6 µg/mL and is not toxic at highest dose of 1000 µg/mL giving safety index value of >130, is considered highly active and on par or ...

                            Brand Name : OT101

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            September 28, 2022

                            Lead Product(s) : Trabedersen

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Recipient : Oncotelic Therapeutics

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Mateon Therapeutics

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                            Medlab Asia & Asia Health
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                            Mateon Therapeutics

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : Trabedersen,Artemisinin

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Oncotelic

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Mateon’s Update on C001 - Global Study for Ot-101 Against Covid-19

                            Details : Mateon has completed the enrollment of its sentinel Part 1 and Part 2 COVID-19 patients which allows for the continuing expansion to the targeted 18 patients in part 1 and 18 patients in part 2. OT-101 is an antisense against the host TGF-β protein.

                            Brand Name : OT-101

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            March 08, 2021

                            Lead Product(s) : Trabedersen,Artemisinin

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Oncotelic

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Mateon Therapeutics

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                            Medlab Asia & Asia Health
                            Not Confirmed

                            Mateon Therapeutics

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : TT-702

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Oceanpine Capital

                            Deal Size : $30.0 million

                            Deal Type : Series A Financing

                            DEALS_DEV arrow-down

                            Teon Therapeutics Completes $30 Million Series A Financing

                            Details : The funds will be used to advance the company’s lead A2BR-selective antagonist TT-702 into the clinic as well as to build the company’s pipeline.

                            Brand Name : TT-702

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            February 23, 2021

                            Lead Product(s) : TT-702

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Oceanpine Capital

                            Deal Size : $30.0 million

                            Deal Type : Series A Financing

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                            04

                            Mateon Therapeutics

                            U.S.A arrow
                            Medlab Asia & Asia Health
                            Not Confirmed

                            Mateon Therapeutics

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : Trabedersen,Undisclosed

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Mateon’s Global Study for OT-101/ Tgf-Β Inhibitor Against Covid-19 Enrolls and Treats Its First Patient

                            Details : C-001 is a Phase 2 randomized, placebo-control study to evaluate safety and efficacy of OT-101 in combination with standard of care on two patient cohorts – 1) mild or moderate disease, and 2) severe disease requiring mechanical ventilation or intubati...

                            Brand Name : OT-101

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            December 30, 2020

                            Lead Product(s) : Trabedersen,Undisclosed

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Mateon Therapeutics

                            U.S.A arrow
                            Medlab Asia & Asia Health
                            Not Confirmed

                            Mateon Therapeutics

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : Combretastatin A1 Diphosphate

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            FDA Granted Pediatric Disease Designation for OXi-4503

                            Details : OXi4503 in combination with standard chemotherapy drug cytarabine was generally well tolerated by adult AML patients and a maximum tolerated dose level of OXi4503 was identified as the recommended dose for further clinical development of this novel two-d...

                            Brand Name : OXi4503

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 16, 2020

                            Lead Product(s) : Combretastatin A1 Diphosphate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Mateon Therapeutics

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                            Medlab Asia & Asia Health
                            Not Confirmed

                            Mateon Therapeutics

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : Artemisinin

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Preclinical

                            Recipient : Asili Research Alliance

                            Deal Size : Undisclosed

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            Mateon and Asili Research Alliance Enter Into Partnership for the Development of Artemisinin Against Covid-19

                            Details : ARTI19 is designed to rapidly establish the clinical efficacy of Artemisinin in mild and moderate COVID-19 patients. In-vitro, the medical grade version of the supplement has proven potency and safety similar to Remdesivir with an EC50 = 0.45 ug/ml and S...

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            July 20, 2020

                            Lead Product(s) : Artemisinin

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Preclinical

                            Recipient : Asili Research Alliance

                            Deal Size : Undisclosed

                            Deal Type : Partnership

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                            07

                            Mateon Therapeutics

                            U.S.A arrow
                            Medlab Asia & Asia Health
                            Not Confirmed

                            Mateon Therapeutics

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : Artemisinin

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Preclinical

                            Recipient : Undisclosed

                            Deal Size : Undisclosed

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Mateon Therapeutics to Fund Observational Studies of Artemisinin in Developing Countries

                            Details : Mateon Therapeutics announced that it will fund observational studies for Artemisinin, an herbal supplement, that demonstrated potent in vitro activity against SARS-CoV-2, the COVID-19 virus.

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            July 13, 2020

                            Lead Product(s) : Artemisinin

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Preclinical

                            Recipient : Undisclosed

                            Deal Size : Undisclosed

                            Deal Type : Funding

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                            08

                            Mateon Therapeutics

                            U.S.A arrow
                            Medlab Asia & Asia Health
                            Not Confirmed

                            Mateon Therapeutics

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : Trabedersen

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Preclinical

                            Recipient : IBM Watson Health

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Mateon is Selected by IBM Watson Health for the Use of IBM Clinical Development Solution for Phase II Clinical...

                            Details : Mateon was approved to use the platform following a review of the program as part of IBM Watson Health’s effort to help support and accelerate promising clinical COVID-19 candidates.

                            Brand Name : OT-101

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            June 24, 2020

                            Lead Product(s) : Trabedersen

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Preclinical

                            Recipient : IBM Watson Health

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            09

                            Mateon Therapeutics

                            U.S.A arrow
                            Medlab Asia & Asia Health
                            Not Confirmed

                            Mateon Therapeutics

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : Trabedersen

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Mateon and GMP to Proceed to Clinical Development of OT-101 and Artemisin

                            Details : GMP and Mateon are working to ensure safety and efficacy of OT-101 and Artemisinin for COVID-19 patients. OT-101 is an antisense against host TGF-β protein required for viral replication.

                            Brand Name : OT-101

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            June 22, 2020

                            Lead Product(s) : Trabedersen

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            Mateon Therapeutics

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                            Medlab Asia & Asia Health
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                            Mateon Therapeutics

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : Trabedersen,Aldesleukin

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Autotelic BIO

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Mateon Announces Achievement of Milestone Under Licensing of OT-101/IL-2 Combination to Autotelic BIO

                            Details : OT-101 has demonstrated robust efficacy against pancreatic cancer, glioblastoma, and melanoma during phase 2 clinical trials. The demonstration that OT-101 will synergize with IL-2 further demonstrate its utility as adjunct to other immunotherapies.

                            Brand Name : OT-101

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            June 10, 2020

                            Lead Product(s) : Trabedersen,Aldesleukin

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Autotelic BIO

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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