7
ALL7
Mustang BioYear
7
ALL2
20221
20214
2020DEALS // DEV.
7
ALL1
Deals6
DevelopmentsCountry
7
ALL7
U.S.A7
ALL6
Inapplicable1
Minaris Regenerative MedicineTherapeutic Area
7
ALL7
Genetic DiseaseStudy Phase
7
ALL7
Phase I/ Phase IIDeal Type
7
ALL1
Agreement6
InapplicableProduct Type
7
ALL7
Cell and Gene therapyDosage Form
7
ALL7
Intravenous InfusionLead Product
7
ALL7
MB-107Target
7
ALL7
IL-2G receptorLead Product(s) : MB-107
Therapeutic Area : Genetic Disease
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : MB-107, Mustang’s lentiviral gene therapy for X-linked severe combined immunodeficiency (“XSCID”), also known as bubble boy disease, in newly diagnosed infants under the age of two.
Product Name : MB-107
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
May 19, 2022
Lead Product(s) : MB-107
Therapeutic Area : Genetic Disease
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : MB-107,Busulfan
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : All 23 treated patients are alive and 20 patients with follow-up greater than 4 months recovered from pre-existing infections, are off protective isolation and prophylactic antimicrobials, and have normal growth velocity.
Product Name : MB-107
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
March 05, 2022
Lead Product(s) : MB-107,Busulfan
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : MB-107,Busulfan
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : FDA removes clinical hold for pivotal Phase 2 MB-107 clinical trial. Mustang will proceed with its plans to initiate the pivotal Phase 2 trial in newly diagnosed XSCID patients.
Product Name : MB-107
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
February 02, 2021
Lead Product(s) : MB-107,Busulfan
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : MB-107,Busulfan
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Minaris Regenerative Medicine
Deal Size : Undisclosed
Deal Type : Agreement
Details : The companies have signed an agreement to enable technology transfer and GMP clinical manufacturing of Mustang’s MB-107 lentiviral gene therapy program for the treatment of X-linked severe combined immunodeficiency, also known as bubble boy disease, in...
Product Name : MB-107
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
November 23, 2020
Lead Product(s) : MB-107,Busulfan
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Minaris Regenerative Medicine
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : MB-107,Busulfan
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : U.S. Food and Drug Administration (“FDA”) has granted Rare Pediatric Disease Designation to MB-107, Mustang’s lentiviral gene therapy for the treatment of X-linked severe combined immunodeficiency (“XSCID”), also known as bubble boy disease, in...
Product Name : MB-107
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
August 17, 2020
Lead Product(s) : MB-107,Busulfan
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : MB-107,Busulfan
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : European Medicines Agency has granted Advanced Therapy Medicinal Product classification to MB-107, Mustang’s lentiviral gene therapy for the treatment of X-linked severe combined immunodeficiency.
Product Name : MB-107
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
April 20, 2020
Lead Product(s) : MB-107,Busulfan
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : MB-107,Busulfan
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : U.S. FDA has granted Orphan Drug Designation to MB-107, Mustang’s lentiviral gene therapy for the treatment of X-linked severe combined immunodeficiency, also known as bubble boy disease, in newly diagnosed infants under the age of two.
Product Name : MB-107
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
February 09, 2020
Lead Product(s) : MB-107,Busulfan
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable