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USA","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Dexmedetomidine Hydrochloride","moa":"Adrenergic receptor-alpha 2","graph1":"Neurology","graph2":"Phase II","graph3":"Teikoku Pharma USA","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Transdermal Patch","sponsorNew":"Teikoku Pharma USA \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Teikoku Pharma USA \/ Inapplicable"},{"orgOrder":0,"company":"BioXcel Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Dexmedetomidine Hydrochloride","moa":"Adrenergic receptor-alpha 2","graph1":"Psychiatry\/Psychology","graph2":"Approved FDF","graph3":"BioXcel Therapeutics","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Sublingual Film","sponsorNew":"BioXcel Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"BioXcel Therapeutics \/ Inapplicable"}]

Find Clinical Drug Pipeline Developments & Deals for Medetomidine Hydrochloride

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01

Lead Product(s) : Dexmedetomidine Hydrochloride

Therapeutic Area : Neurology

Study Phase : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : Dr. Reddy’s Dexmedetomidine Hydrochloride in 0.9% Sodium Chloride Injection is available in 200 mcg/50 mL (4 mcg/mL) and 400 mcg/100 mL (4 mcg/mL) in 50 mL and 100 mL clear glass vials, respectively.

Product Name : Dexmedetomidine Hydrochloride-Generic

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

September 25, 2020

Lead Product(s) : Dexmedetomidine Hydrochloride

Therapeutic Area : Neurology

Highest Development Status : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

Dr Reddy Company Banner

02

Interphex
Not Confirmed
Interphex
Not Confirmed

Details : Strengthened cash position will support advancement of SERENITY trial, to evaluate BXCL501, an ODT of dexmedetomidine, for agitation associated with bipolar disorders or schizophrenia.

Product Name : Igalmi

Product Type : Other Small Molecule

Upfront Cash : Undisclosed

March 11, 2025

Lead Product(s) : Dexmedetomidine Hydrochloride

Therapeutic Area : Psychiatry/Psychology

Highest Development Status : Approved FDF

Sponsor : Undisclosed

Deal Size : $14.0 million

Deal Type : Financing

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03

Interphex
Not Confirmed
Interphex
Not Confirmed

Details : An orally dissolving film formulation of BXCL501 (dexmedetomidine), in the at-home setting is being investigated for acute treatment of agitation associated with bipolar disorders or schizophrenia.

Product Name : Igalmi

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

March 07, 2025

Lead Product(s) : Dexmedetomidine Hydrochloride

Therapeutic Area : Psychiatry/Psychology

Highest Development Status : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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04

Interphex
Not Confirmed
Interphex
Not Confirmed

Details : The proceeds from the financing will be used to commercialize Igalmi (dexmedetomidine HCl). It is being indicated for the treatment of agitation associated with schizophrenia.

Product Name : Igalmi

Product Type : Other Small Molecule

Upfront Cash : Undisclosed

March 04, 2025

Lead Product(s) : Dexmedetomidine Hydrochloride

Therapeutic Area : Psychiatry/Psychology

Highest Development Status : Approved FDF

Sponsor : Rodman & Renshaw LLC

Deal Size : $14.0 million

Deal Type : Public Offering

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05

Interphex
Not Confirmed
Interphex
Not Confirmed

Details : BXCL501 (dexmedetomidine Hc;) is being evaluated in the late-stage clinical trials studies for the treatment of Agitation Associated with Bipolar Disorders and Schizophrenia.

Product Name : Igalmi

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

December 11, 2024

Lead Product(s) : Dexmedetomidine Hydrochloride

Therapeutic Area : Psychiatry/Psychology

Highest Development Status : Phase III

Sponsor : CSL Vifor

Deal Size : Inapplicable

Deal Type : Inapplicable

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06

Interphex
Not Confirmed
Interphex
Not Confirmed

Details : A generic version of Precedex (dexmedetomidine hydrochloride), an alpha2-adrenergic agonist with sedative properties used for short-term intravenous sedation.

Product Name : Precedex-Generic

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

November 18, 2024

Lead Product(s) : Dexmedetomidine Hydrochloride

Therapeutic Area : Neurology

Highest Development Status : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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07

Interphex
Not Confirmed
Interphex
Not Confirmed

Details : BXCL501 (dexmedetomidine HCl) is an adrenergic receptor alpha-2 agonist, small molecule drug candidate, which is currently being evaluated for agitation associated With alzheimer’s dementia.

Product Name : Igalmi

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

October 04, 2024

Lead Product(s) : Dexmedetomidine Hydrochloride

Therapeutic Area : Neurology

Highest Development Status : Phase II

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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08

Interphex
Not Confirmed
Interphex
Not Confirmed

Details : BXCL501 (dexmedetomidine HCl) is an adrenergic receptor alpha-2 agonist, which is currently being evaluated for the treatment of Bipolar Disorder and Schizophrenia.

Product Name : Igalmi

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

September 19, 2024

Lead Product(s) : Dexmedetomidine Hydrochloride

Therapeutic Area : Psychiatry/Psychology

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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09

Interphex
Not Confirmed
Interphex
Not Confirmed

Details : The company will use net proceeds for ongoing clinical trials and commercialization of Igalmi (dexmedetomidine), for treating agitation associated with schizophrenia or bipolar disorder.

Product Name : Igalmi

Product Type : Other Small Molecule

Upfront Cash : Undisclosed

August 02, 2024

Lead Product(s) : Dexmedetomidine Hydrochloride

Therapeutic Area : Psychiatry/Psychology

Highest Development Status : Approved FDF

Sponsor : BofA Securities

Deal Size : $60.0 million

Deal Type : Public Offering

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10

Interphex
Not Confirmed
Interphex
Not Confirmed

Details :

Product Name : Precedex-Generic

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

July 25, 2024

Lead Product(s) : Dexmedetomidine Hydrochloride

Therapeutic Area : Neurology

Highest Development Status : Approved FDF

Sponsor : Sagent Pharmaceuticals

Deal Size : Inapplicable

Deal Type : Inapplicable

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