Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : MTX-463
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Eli Lilly
Deal Size : $786.0 million
Deal Type : Licensing Agreement
Mediar Therapeutics Signs Global License with Lilly for WISP1 Antibody in IPF
Details : Under the licensing agreement, Lilly will have the right to lead all further clinical development and commercialization of the MTX-463 for treating idiopathic pulmonary fibrosis.
Product Name : MTX-463
Product Type : Antibody
Upfront Cash : Undisclosed
January 10, 2025
Lead Product(s) : MTX-463
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Eli Lilly
Deal Size : $786.0 million
Deal Type : Licensing Agreement
Lead Product(s) : MTX-474
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Mediar Therapeutics Starts Second Program of Antibodies to Halt Fibrosis
Details : MTX-474 is a first-in-class human IgG1 antibody designed to neutralize the EphrinB2 signaling that causes the onset and progression of fibrosis.
Product Name : MTX-474
Product Type : Large molecule
Upfront Cash : Not Applicable
August 07, 2024
Lead Product(s) : MTX-474
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : MTX-463
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Mediar Advances Fibrosis To Clinic With First Cohort Dosing In Phase 1 Of MTX-463
Details : MTX-463 is an immunoglobin G1 (IgG1) monoclonal antibody directed against WNT-inducible signaling pathway protein 1 (WISP1). It is being evaluated for the treatment of idiopathic pulmonary fibrosis.
Product Name : MTX-463
Product Type : Large molecule
Upfront Cash : Not Applicable
May 07, 2024
Lead Product(s) : MTX-463
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Antibody
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : Preclinical
Sponsor : Novartis Venture Fund
Deal Size : $105.0 million
Deal Type : Financing
Details : The series A financing will support advancement of the company’s portfolio of first-in-class antibody treatments, which offer unique potential to address fibrosis at varying stages of the disease, with two programs advancing into human studies in 2024.
Product Name : Undisclosed
Product Type : Large molecule
Upfront Cash : Undisclosed
March 15, 2023
Lead Product(s) : Antibody
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : Preclinical
Sponsor : Novartis Venture Fund
Deal Size : $105.0 million
Deal Type : Financing
Lead Product(s) : Neutralizing antibodies
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : Discovery
Sponsor : Distributed Bio
Deal Size : Undisclosed
Deal Type : Partnership
Distributed Bio Partners With Mediar Therapeutics, Inc.
Details : Under the terms of this partnership, Distributed Bio will use its SuperHuman2.0 Antibody Discovery platform to identify lead antibodies for Mediar programs.
Product Name : Undisclosed
Product Type : Large molecule
Upfront Cash : Undisclosed
June 03, 2020
Lead Product(s) : Neutralizing antibodies
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : Discovery
Sponsor : Distributed Bio
Deal Size : Undisclosed
Deal Type : Partnership