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    [{"orgOrder":0,"company":"Medicago","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"CANADA","productType":"Vaccine","year":"2020","type":"Not Applicable","leadProduct":"Virus-Like Particle","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Preclinical","graph3":"Medicago","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"","sponsorNew":"Medicago \/ Not Applicable","highestDevelopmentStatusID":"4","companyTruncated":"Medicago \/ Not Applicable"},{"orgOrder":0,"company":"Medicago","sponsor":"GSK","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Vaccine","year":"2020","type":"Collaboration","leadProduct":"CoVLP vaccine","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Phase I","graph3":"Medicago","amount2":0,"highestDevelopmentShortName":"Ph 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                            Lead Product(s) : Recombinant Adjuvanted Plant-based Virus-like Particle

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Medicago Announces Publication of Phase 3 COVID-19 Vaccine Study Results in New England Journal of Medicine

                            Details : COVIFENZ, COVID-19 vaccine (plant-based virus-like particles [VLP], recombinant, adjuvanted), is indicated for active immunization to prevent coronavirus disease caused by severe acute respiratory syndrome coronavirus 2 in individuals 18 to 64 years of a...

                            Brand Name : Covifenz

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            May 05, 2022

                            Lead Product(s) : Recombinant Adjuvanted Plant-based Virus-like Particle

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : Recombinant Adjuvanted Plant-based Virus-like Particle

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved

                            Sponsor : GSK

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Medicago and GSK Announce the Approval by Health Canada of Covifenz®, an Adjuvanted Plant-based COVID-19 Vacc...

                            Details : COVIFENZ® uses Coronavirus-Like Particle (CoVLP) technology with the vaccine composed of recombinant spike (S) glycoprotein expressed as virus-like particles (VLPs) co-administered with GSK’s pandemic adjuvant.

                            Brand Name : GSK4362620A

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            February 24, 2022

                            Lead Product(s) : Recombinant Adjuvanted Plant-based Virus-like Particle

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved

                            Sponsor : GSK

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : Recombinant Coronavirus Virus-Like Particle COVID-19 vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : GSK

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Medicago Submits Phase 3 Data to Health Canada for Its Plant-Based COVID-19 Vaccine Candidate

                            Details : Apart from Canada regulatory filing has also been initiated for USFDA and MHRA for CoVLP (Recombinant Coronavirus Virus-Like Particle COVID-19 vaccine), the first-ever plant-based vaccine, final portion of data submitted as part of New Drug Submission CO...

                            Brand Name : CoVLP

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            December 16, 2021

                            Lead Product(s) : Recombinant Coronavirus Virus-Like Particle COVID-19 vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : GSK

                            Deal Size : Not Applicable

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                            Lead Product(s) : CoVLP Adjuvanted Vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : GSK

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Medicago and GSK Announce Positive Phase 3 Efficacy and Safety Results for Adjuvanted Plant-Based COVID-19 Vac...

                            Details : Covid19 Vaccine candidate demonstrated efficacy against all variants seen in the study, including 75.3% efficacy against COVID-19 of any severity caused by the globally dominant Delta variant.

                            Brand Name : Undisclosed

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            December 07, 2021

                            Lead Product(s) : CoVLP Adjuvanted Vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : GSK

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : Recombinant Coronavirus Virus-Like Particle COVID-19 vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : GSK

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Medicago and GSK Announce Positive Interim Phase 2 Results for Adjuvanted Covid-19 Vaccine Candidate

                            Details : The Phase 3 portion is an event-driven, randomized, observer-blinded, crossover placebo-controlled design that will evaluate the efficacy and safety of the CoVLP formulation, compared to placebo, in up to 30,000 subjects.

                            Brand Name : CoVLP

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            May 18, 2021

                            Lead Product(s) : Recombinant Coronavirus Virus-Like Particle COVID-19 vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : GSK

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : Recombinant Coronavirus Virus-Like Particle COVID-19 vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Health Canada to Start Real-Time Review of Medicago COVID-19 Vaccine

                            Details : Medicago’s plant-derived vaccine candidate against COVID-19 uses Coronavirus-Like-Particle (CoVLP) technology with the vaccine composed of recombinant spike (S) glycoprotein expressed as virus-like-particles (VLPs) co-administered with GSK’s pandemic...

                            Brand Name : CoVLP

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            April 23, 2021

                            Lead Product(s) : Recombinant Coronavirus Virus-Like Particle COVID-19 vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

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                            Lead Product(s) : Recombinant Coronavirus Virus-Like Particle COVID-19 vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : GSK

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Brazilian Health Regulator Anvisa Authorizes Trials for GSK-Medicago COVID Vaccine

                            Details : Anvisa said the companies were authorized to conduct phase 3 trials in the country. The companies are planning to test the new vaccines in around 30,000 people, in the U.S., Canada, Europe and Latin America. Brazil may have around 3,500 volunteers for th...

                            Brand Name : Undisclosed

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            April 08, 2021

                            Lead Product(s) : Recombinant Coronavirus Virus-Like Particle COVID-19 vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : GSK

                            Deal Size : Not Applicable

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                            Lead Product(s) : Recombinant Coronavirus Virus-Like Particle COVID-19 vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II/ Phase III

                            Sponsor : National Institutes of Health

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Medicago and GSK Start Phase 3 Trial of Adjuvanted Covid-19 Vaccine Candidate

                            Details : Medicago's plant-derived vaccine candidate against COVID-19 uses Coronavirus-Like-Particle (CoVLP) technology with the vaccine composed of recombinant spike (S) glycoprotein expressed as virus-like-particles (VLPs) co-administered with GSK's pandemic adj...

                            Brand Name : Undisclosed

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            March 16, 2021

                            Lead Product(s) : Recombinant Coronavirus Virus-Like Particle COVID-19 vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : National Institutes of Health

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : Recombinant Coronavirus Virus-Like Particle COVID-19 vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II/ Phase III

                            Sponsor : GSK

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Medicago Announces Positive Phase 1 Results for Its Covid-19 Vaccine Candidate

                            Details : The results of the trial demonstrated that 100 per cent of subjects developed a promising antibody response after two doses of Medicago’s COVID-19 adjuvanted vaccine candidate.

                            Brand Name : Undisclosed

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            November 09, 2020

                            Lead Product(s) : Recombinant Coronavirus Virus-Like Particle COVID-19 vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : GSK

                            Deal Size : Not Applicable

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                            Lead Product(s) : Recombinant Coronavirus Virus-Like Particle COVID-19 vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Medicago Begins Phase I Clinical Trials for its COVID-19 Vaccine Candidate

                            Details : The Phase I clinical trial is a randomized, partially blinded study of 180 normal healthy subjects and will evaluate dosages of 3.75, 7.5 or 15 micrograms of the recombinant CoVLP vaccine candidate alone or with an adjuvant in a prime-boost regimen.

                            Brand Name : Undisclosed

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            July 14, 2020

                            Lead Product(s) : Recombinant Coronavirus Virus-Like Particle COVID-19 vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

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