Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : MDG1015
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Medigene Gets FDA Clearance for MDG1015, a TCR-T Therapy for Solid Tumors
Details : MDG1015 is a first-in-class, TCR-T therapy targeting NY-ESO-1/ LAGE-1a. It is being developed for gastric cancer, ovarian cancer, myxoid/round cell liposarcoma and synovial sarcoma.
Brand Name : MDG1015
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
September 05, 2024
Lead Product(s) : MDG1015
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Gene-based Therapy
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : WuXi Biologics
Deal Size : Undisclosed
Deal Type : Collaboration
Medigene and WuXi Biologics Collaborate on Off-the-Shelf TCR-Guided T Cell Engagers
Details : The collaboration combines the respective expertise of each company with Medigene’s 3S TCR generation and WuXi Biologics’ unique anti-CD3 mAb for the treatment of cancers.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
August 08, 2024
Lead Product(s) : Gene-based Therapy
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : WuXi Biologics
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : MDG2021,PD1-41BB
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Medigene Announces Lead Selection for KRAS-targeting TCR-T in Solid Tumors
Details : MDG2021, a TCR-T therapy targeting KRASG12D with HLA-A*11 being developed in combination with the Company’s PD1-41BB costimulatory switch protein, for solid tumors.
Brand Name : MDG2021
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
June 20, 2024
Lead Product(s) : MDG2021,PD1-41BB
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Medigene-BioNTech Collaboration Agreement Extended Beyond Initial Term
Details : The collaboration aims to advance T cell receptor immunotherapies against cancer
Brand Name : T-cell Therapy
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
May 21, 2024
Lead Product(s) : MDG1015
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Medigene Selects Indication for 3rd Generation TCR-T Therapy in Solid Tumors
Details : MDG1015, a TCR-T therapy targeting NY-ESO-1/LAGE-1a, is in trials for gastric, ovarian cancers, and soft tissue sarcomas.
Brand Name : MDG1015
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
February 12, 2024
Lead Product(s) : MDG1015
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : MDG1015,PD1-41BB
Therapeutic Area : Oncology
Study Phase : IND Enabling
Recipient : AGC Biologics
Deal Size : Undisclosed
Deal Type : Agreement
AGC Biologics Signs TCR-T Cell Services Agreement to Support Medigene’s New Cell Therapy Product
Details : Under the agreement, AGC Biologics is providing autologous production for MDG1015, a third generation TCR-T therapy, focused on the treatment of solid cancers, supporting Medigene’s IND filing and clinical trials.
Brand Name : MDG1015
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
October 25, 2023
Lead Product(s) : MDG1015,PD1-41BB
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Recipient : AGC Biologics
Deal Size : Undisclosed
Deal Type : Agreement
Details : MDG2011, a T cell receptor engineered T cell (TCR-T) therapy targeting KRAS (Kirsten rat sarcoma viral oncogene homologue) G12V with HLA-A*11 and being developed in combination with the Company’s PD1-41BB costimulatory switch protein (CSP) technology.
Brand Name : MDG2011
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
September 18, 2023
Lead Product(s) : TCR-T-based Therapy
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Medigene AG Expands Patent Portfolio for its End-to-End Platform
Details : The patent issued by the Japan Patent Office protecting its PD1-41BB switch receptor. Medigene's PD1-41BB costimulatory switch receptor technology was developed by its partner Helmholtz Munich and is exclusively licensed to Medigene.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
May 22, 2023
Lead Product(s) : TCR-T-based Therapy
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : TCR-T-based Therapy
Therapeutic Area : Oncology
Study Phase : Discovery
Recipient : Helmholtz Zentrum München
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Medigene Acquires Worldwide, Exclusive License Of CD40L-CD28 Costimulatory Switch Receptor
Details : Under the agreement, Medigene accelerates the expansion of its end-to-end platform of multiple, combinable, exclusive and proprietary technologies with the potential to create best-in-class T cell receptor engineered T cell (TCR-T) therapies for patients...
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
May 02, 2023
Lead Product(s) : TCR-T-based Therapy
Therapeutic Area : Oncology
Highest Development Status : Discovery
Recipient : Helmholtz Zentrum München
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : T cell-based Therapy
Therapeutic Area : Oncology
Study Phase : Undisclosed
Sponsor : National Cancer Institute
Deal Size : Undisclosed
Deal Type : Agreement
Medigene Enters Cooperative Research and Development Agreement with the National Cancer Institute
Details : The companies will collaborate to evaluate the potential of Medigene’s proprietary T cell receptors (TCRs) to be used in new cell constructs for the treatment of solid tumors in T cell-based Therapy.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
April 03, 2023
Lead Product(s) : T cell-based Therapy
Therapeutic Area : Oncology
Highest Development Status : Undisclosed
Sponsor : National Cancer Institute
Deal Size : Undisclosed
Deal Type : Agreement
LOOKING FOR A SUPPLIER?