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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : Zynrelef (bupivacaine, meloxicam) is an investigational local anesthetic given periarticularly as an extended-release solution for postoperative pain.

                          Brand Name : Zynrelef

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 25, 2024

                          Lead Product(s) : Bupivacaine,Meloxicam

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved

                          Sponsor : Mayo Clinic

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : AXS-07 (meloxicam-rizatriptan) is a novel, oral, rapidly absorbed, COX-2 inhibitor & 5-HT1B/1D agonist combinationed being investigating for the acute treatment of migraine.

                          Brand Name : AXS-07

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 04, 2024

                          Lead Product(s) : Meloxicam,Rizatriptan Benzoate

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : Zynrelef (bupivacaine, meloxicam) is an investigational local anesthetic given periarticularly as an extended-release solution for postoperative pain. The FDA has set a PDUFA date of 23 Sep 2024.

                          Brand Name : Zynrelef

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          July 02, 2024

                          Lead Product(s) : Bupivacaine,Meloxicam

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase III

                          Sponsor : Mayo Clinic

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : Company submmitted Prior Approval Supplement to the FDA for ZYNRELEF® (bupivacaine and meloxicam) extended-release solution Vial Access Needle kit.

                          Brand Name : Zynrelef

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          May 30, 2024

                          Lead Product(s) : Bupivacaine,Meloxicam

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : The partnership aims to expand the sales network supporting Zynrelef (bupivacaine and meloxicam) extended-release solution, the first and only dual-acting local anesthetic, for post-operative pain.

                          Brand Name : Zynrelef

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          January 07, 2024

                          Lead Product(s) : Bupivacaine,Meloxicam

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved

                          Sponsor : Heron Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          06

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : The Company intends to use the net proceeds from this offering for pipeline development activities including, Anjeso (meloxicam), a nonsteroidal anti-inflammatory drug (NSAID) to treat symptoms of Osteoarthritis, Rheumatoid Arthritis, and Moderate-to-Sev...

                          Brand Name : Anjeso

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          April 26, 2023

                          Lead Product(s) : Meloxicam

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved

                          Sponsor : H.C. Wainwright & Co.

                          Deal Size : $4.0 million

                          Deal Type : Public Offering

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                          07

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : ZYNRELEF is the first and only dual-acting local anesthetic that delivers a fixed-dose combination of the local anesthetic bupivacaine and a low dose of nonsteroidal anti-inflammatory drug meloxicam.

                          Brand Name : Zynrelef

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          December 29, 2022

                          Lead Product(s) : Bupivacaine,Meloxicam

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : ANJESO (meloxicam) is a nonsteroidal anti-inflammatory drug (NSAID). It is a sterile opaque, pale-yellow, aqueous dispersion containing the active pharmaceutical ingredient meloxicam for intravenous administration.

                          Brand Name : Anjeso

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          December 06, 2022

                          Lead Product(s) : Meloxicam

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved

                          Sponsor : H.C. Wainwright & Co.

                          Deal Size : $5.0 million

                          Deal Type : Public Offering

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                          09

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : ANJESO (meloxicam) is a long-acting NSAID with preferential COX-2 inhibition that possesses anti-inflammatory, analgesic, and antipyretic activities, which are believed to be related to the inhibition of COX and subsequent reduction in prostaglandin bios...

                          Brand Name : Anjeso

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          December 02, 2022

                          Lead Product(s) : Meloxicam

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved

                          Sponsor : H.C. Wainwright & Co.

                          Deal Size : $5.0 million

                          Deal Type : Public Offering

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                          10

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : AXS-07 is a novel, oral, rapidly absorbed, multi-mechanistic investigational medicine for the acute treatment of migraine, consisting of MoSEIC™ meloxicam and rizatriptan.

                          Brand Name : AXS-07

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 29, 2022

                          Lead Product(s) : Meloxicam,Rizatriptan Benzoate

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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