Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Midazolam,Ketamine Hydrochloride
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Melt Reports Positive Phase 3 Results for MELT-300 in Opioid-Free Cataract Sedation
Details : MELT-300, a non-intravenous, non-opioid tablet that blends fixed doses of midazolam and ketamine. This medication is designed for procedural sedation during cataract surgery.
Brand Name : MELT-300
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 20, 2024
Lead Product(s) : Midazolam,Ketamine Hydrochloride
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Midazolam,Ketamine Hydrochloride
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Melt Doses Last Patient in Phase 3 Study For MELT-300 Sedation
Details : MELT-300, a non-intravenous, non-opioid tablet that blends fixed doses of midazolam and ketamine. This medication is designed for procedural sedation during cataract surgery.
Brand Name : MELT-300
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 10, 2024
Lead Product(s) : Midazolam,Ketamine Hydrochloride
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Midazolam,Ketamine Hydrochloride
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Melt Pharma Doses First Patient in Phase 3 Trial of MELT-300 for Opioid-Free Sedation
Details : MELT-300, a non-intravenous, non-opioid tablet that blends fixed doses of midazolam and ketamine is being investigated for procedural sedation during cataract surgery.
Brand Name : MELT-300
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 06, 2024
Lead Product(s) : Midazolam,Ketamine Hydrochloride
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Midazolam,Ketamine Hydrochloride
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Newbridge Securities Corporation
Deal Size : $24.0 million
Deal Type : Series B Financing
Melt Pharmaceuticals Closes $24 Million Series B Preferred Stock Financing
Details : The funding will advance MELT-300, a non-intravenous, non-opioid tablet combining midazolam and ketamine, designed for procedural sedation during cataract surgery.
Brand Name : MELT-300
Molecule Type : Small molecule
Upfront Cash : Undisclosed
April 02, 2024
Lead Product(s) : Midazolam,Ketamine Hydrochloride
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Newbridge Securities Corporation
Deal Size : $24.0 million
Deal Type : Series B Financing
Lead Product(s) : Midazolam,Ketamine Hydrochloride
Therapeutic Area : Neurology
Study Phase : Phase II
Recipient : Catalent Pharma Solutions
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Under the agreement, Melt Pharmaceuticals will utilize Catalent’s proprietary Zydis® orally disintegrating tablet fast-dissolve technology with MELT-300 (midazolam), a sublingual, needle- and opioid-free patented formulation for procedural sedation du...
Brand Name : Melt-300
Molecule Type : Small molecule
Upfront Cash : Undisclosed
September 26, 2023
Lead Product(s) : Midazolam,Ketamine Hydrochloride
Therapeutic Area : Neurology
Highest Development Status : Phase II
Recipient : Catalent Pharma Solutions
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Midazolam,Ketamine Hydrochloride
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : MELT-300 combines fixed doses of midazolam (3mg) and ketamine (50mg) in one rapidly dissolving tablet (RDT) that is administered sublingually for procedural sedation during cataract surgery.
Brand Name : MELT-300
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 21, 2022
Lead Product(s) : Midazolam,Ketamine Hydrochloride
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Midazolam,Ketamine Hydrochloride
Therapeutic Area : Ophthalmology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : MELT-300 combines fixed doses of midazolam (3mg) and ketamine (50mg) in one dissolvable tablet that is administered sublingually for procedural sedation and analgesia during cataract surgery.
Brand Name : MELT-300
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 27, 2022
Lead Product(s) : Midazolam,Ketamine Hydrochloride
Therapeutic Area : Ophthalmology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Ketamine Hydrochloride,Midazolam
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Catalent Pharma Solutions
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : MELT-210 is a fixed dose of 3 mg of midazolam formulated in a proprietary rapidly dissolving sublingual tablet using its proprietary Zydis® orally disintegrating tablet (ODT) technology to create a tablet that dissolves quickly when placed under the ton...
Brand Name : MELT-210
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 04, 2022
Lead Product(s) : Ketamine Hydrochloride,Midazolam
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Catalent Pharma Solutions
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Midazolam,Ketamine Hydrochloride
Therapeutic Area : Neurology
Study Phase : Phase I
Sponsor : Harrow Health
Deal Size : Undisclosed
Deal Type : Financing
Harrow Health Provides $13.5 Million Senior Secured Loan to Melt Pharmaceuticals
Details : Melt Pharmaceuticals will use the proceeds to conduct Phase 2 efficacy study for the lead drug candidate, MELT-300, a combination of midazolam and ketamine in a rapidly dissolving, sublingual tablet to provide sedation and analgesia for patients undergoi...
Brand Name : MELT-300
Molecule Type : Small molecule
Upfront Cash : Undisclosed
September 02, 2021
Lead Product(s) : Midazolam,Ketamine Hydrochloride
Therapeutic Area : Neurology
Highest Development Status : Phase I
Sponsor : Harrow Health
Deal Size : Undisclosed
Deal Type : Financing
Lead Product(s) : Midazolam,Ketamine Hydrochloride
Therapeutic Area : Neurology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : MELT is a patented combination of midazolam and ketamine in a rapidly dissolving, sublingual tablet to provide sedation and analgesia for patients undergoing cataract surgery.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 09, 2021
Lead Product(s) : Midazolam,Ketamine Hydrochloride
Therapeutic Area : Neurology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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