Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : EVOLVE-104
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : EvolveImmune Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
EvolveImmune Enters Research Deal for Bladder Cancer Tumor Target
Details : The collaboration aims to investigate the expression of a novel tumor target, UL Binding Protein 2 (ULBP2) in muscle-invasive bladder cancer.
Product Name : EVOLVE-104
Product Type : Antibody-drug Conjugate
Upfront Cash : Undisclosed
April 08, 2025
Lead Product(s) : EVOLVE-104
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : EvolveImmune Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Caribou Biosciences
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : In-licensing these anti-CD371 scFvs further expands Caribou’s pipeline of allogeneic cell therapies for hematological malignancies. CB-010, Caribou’s lead allogeneic CAR-T program, targets CD19 and has been cleared by the FDA for clinical evaluation.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
November 18, 2020
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Caribou Biosciences
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : TEM8 may enable pre-screening of solid tumors to determine if SVV-001 might be effective in that patient. This discovery is based on research from Charles Rudin, MD., Ph.D. and colleagues at MSK.
Product Name : SVV-001
Product Type : Microorganism
Upfront Cash : Undisclosed
August 31, 2020
Lead Product(s) : h5A10
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Diaprost
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Diaprost AB Acquires Rights to use of PSA Antibodies from Memorial Sloan Kettering Cancer Center
Details : Diaprost’s h5A10 is already in pre-clinical development for the treatment of prostate cancer. h5A10 displays high levels of specificity and affinity to PSA as well as successful tissue biodistribution and cellular internalization.
Product Name : h5A10
Product Type : Antibody
Upfront Cash : Undisclosed
August 25, 2020
Lead Product(s) : h5A10
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Diaprost
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : OTQ923
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
A Phase I/II Study of a New Gene Therapy for Sickle Cell Disease
Details : First-in-Patient Phase I/II Clinical Study to Investigate the Safety and Efficacy of Genome-edited Hematopoietic Stem and Progenitor Cells in Subjects with Severe Complications of Sickle Cell Disease.
Product Name : OTQ923
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
August 10, 2020
Lead Product(s) : OTQ923
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Hydroxychloroquine Sulphate
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Company's to donate Hydroxychloroquine tablets to support a Phase 2 clinical trial exploring hydroxychloroquine as preventive treatment for COVID-19 in patients with cancer under radiation therapy.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
July 05, 2020
Lead Product(s) : Hydroxychloroquine Sulphate
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Minerva Biotechnologies has licensed from Memorial Sloan Kettering Cancer Center (MSK) “1XX” technology for use with Minerva’s proprietary anti-MUC1* antibodies to increase CAR T cell persistence in patients.
Product Name : huMNC2-CAR44
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
June 22, 2020