Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Antibody-based Therapy
Therapeutic Area : Oncology
Study Phase : Discovery Platform
Recipient : AbSci
Deal Size : Undisclosed
Deal Type : Collaboration
Absci Teams with Global Cancer Center to Discover Therapeutics Using Generative AI
Details : The collaboration unites Absci’s Generative AI Drug Creation Platform with leading oncology experts to discover and develop up to six novel cancer therapeutics.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
August 12, 2024
Lead Product(s) : Antibody-based Therapy
Therapeutic Area : Oncology
Highest Development Status : Discovery Platform
Recipient : AbSci
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : CAR-T Based Therapy
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : OSE Immunotherapeutics SA
Deal Size : Undisclosed
Deal Type : Collaboration
OSE Immunotherapeutics Announces CAR T-cell Therapies Agreement
Details : This new agreement is based on the initial multi-year research collaboration between MSK and OSE Immunotherapeutics to explore the preclinical potential against IL-7R Acute Lymphoblastic Leukemia.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
June 24, 2024
Lead Product(s) : CAR-T Based Therapy
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : OSE Immunotherapeutics SA
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : CAR-T Cell Therapy
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : Alaya.bio
Deal Size : Undisclosed
Deal Type : Collaboration
Alaya.Bio Announces Collaboration with Top Global Cancer Center for In Situ CAR-T Therapy
Details : The collaboration will advance research into in situ CAR-T cell therapies and evaluate their potential to deliver faster, more effective, and cost-efficient treatments for patients.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
January 18, 2024
Lead Product(s) : CAR-T Cell Therapy
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : Alaya.bio
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Galinpepimut-S,Nivolumab
Therapeutic Area : Oncology
Study Phase : Phase I
Recipient : Sellas Life Sciences Group
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : SLS-001 (galinpepimut-S) is an immunotherapeutic which targets the Wilms Tumor 1 (WT1) protein and which is investigated in Combined with Opdivo® in Advanced Malignant Pleural Mesothelioma.
Brand Name : SLS-001
Molecule Type : Vaccine
Upfront Cash : Not Applicable
June 28, 2023
Lead Product(s) : Galinpepimut-S,Nivolumab
Therapeutic Area : Oncology
Highest Development Status : Phase I
Recipient : Sellas Life Sciences Group
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Galinpepimut-s
Therapeutic Area : Oncology
Study Phase : Phase III
Recipient : Sellas Life Sciences Group
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Galinpepimut-S (GPS) is an immunotherapeutic which targets the Wilms Tumor 1 (WT1) protein which is present and over-expressed in an array of hematological malignancies and solid tumors.
Brand Name : SLS-001
Molecule Type : Vaccine
Upfront Cash : Not Applicable
November 14, 2022
Lead Product(s) : Galinpepimut-s
Therapeutic Area : Oncology
Highest Development Status : Phase III
Recipient : Sellas Life Sciences Group
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Naxitamab,GM-CSF
Therapeutic Area : Oncology
Study Phase : Approved
Recipient : Y-mAbs Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Y-mAbs Announces Regulatory Filing for DANYELZA® (naxitamab-gqgk) in Brazil
Details : DANYELZA (naxitamab-gqgk) is indicated, in combination with granulocyte-macrophage colony-stimulating factor for treatment of pediatric patients 1 year of age and older and adult patients.
Brand Name : Danyelza
Molecule Type : Large molecule
Upfront Cash : Not Applicable
September 26, 2022
Lead Product(s) : Naxitamab,GM-CSF
Therapeutic Area : Oncology
Highest Development Status : Approved
Recipient : Y-mAbs Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : GD2-SADA,177Lu-DOTA
Therapeutic Area : Oncology
Study Phase : Phase I
Recipient : Y-mAbs Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Y-mAbs' Announces Clearance of IND for GD2-SADA
Details : The GD2-SADA construct was created using our SADA technology, utilizes a pre-targeted payload delivery method where antibody constructs assemble in tetramers and bind to the tumor target.
Brand Name : GD2-SADA
Molecule Type : Large molecule
Upfront Cash : Not Applicable
July 12, 2022
Lead Product(s) : GD2-SADA,177Lu-DOTA
Therapeutic Area : Oncology
Highest Development Status : Phase I
Recipient : Y-mAbs Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : TCR Mimic CAR-T Cell Therapy
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : Eureka Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : In the study, anti-NDC80 TCRm-redirected T cells demonstrated high specificity in recognizing and killing multiple cancer cell lines. Moreover, no toxicities to healthy leukocytes and hematopoietic stem cells were observed.
Brand Name : NDC80
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
June 06, 2022
Lead Product(s) : TCR Mimic CAR-T Cell Therapy
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : Eureka Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : In Vivo CAR-X Products
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : Abintus Bio
Deal Size : Undisclosed
Deal Type : Agreement
Details : Under the terms of agreement, Memorial Sloan Kettering Cancer Center will use of its next generation signaling technology (“1XX”) in Abintus’ In Vivo CAR-X products.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
November 17, 2021
Lead Product(s) : In Vivo CAR-X Products
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : Abintus Bio
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Galinpepimut-S,Nivolumab,Sargramostim
Therapeutic Area : Oncology
Study Phase : Phase I
Recipient : Sellas Life Sciences Group
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The safety profile of the GPS-nivolumab combination was similar to that seen with nivolumab alone, with the addition of only low-grade, temporary local reactions at the GPS injection site, consistent with previously performed clinical studies with GPS.
Brand Name : SLS-001
Molecule Type : Vaccine
Upfront Cash : Not Applicable
June 24, 2021
Lead Product(s) : Galinpepimut-S,Nivolumab,Sargramostim
Therapeutic Area : Oncology
Highest Development Status : Phase I
Recipient : Sellas Life Sciences Group
Deal Size : Not Applicable
Deal Type : Not Applicable
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