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II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Merck & Co \/ Rexahn Pharmaceuticals Inc","highestDevelopmentStatusID":"8","companyTruncated":"Merck & Co \/ Rexahn Pharmaceuticals Inc"},{"orgOrder":0,"company":"Merck & Co","sponsor":"Bill & Melinda Gates Foundation","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Licensing Agreement","leadProduct":"MK-7762","moa":"||Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Preclinical","graph3":"Merck & Co","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Merck & Co \/ Bill & Melinda Gates Foundation","highestDevelopmentStatusID":"4","companyTruncated":"Merck & Co \/ Bill & Melinda Gates Foundation"},{"orgOrder":0,"company":"Merck & Co","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Vaccine","year":"2022","type":"Inapplicable","leadProduct":"HPV Quadrivalent Types 6, 11, 16, and 18 Vaccine Recombinant","moa":"Undisclosed","graph1":"Oncology","graph2":"Approved FDF","graph3":"Merck & Co","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intramuscular Injection","sponsorNew":"Merck & Co \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Merck & Co \/ Inapplicable"}]

    Find Clinical Drug Pipeline Developments & Deals by Merck & Co

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                            01

                            Organon

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                            Lead Product(s) : Tocilizumab

                            Therapeutic Area : Immunology

                            Study Phase : Approved FDF

                            Recipient : Biogen

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Organon Acquires Tofidenc, A Commercialized Biosimilar to Actemr in U.S

                            Details : Through this acquisition, Organon enhances and broadens its U.S. biosimilars portfolio, gaining commercial rights in the US for tofidence (tocilizumab), an intravenous biosimilar to actemra.

                            Product Name : Tofidence

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            April 01, 2025

                            Lead Product(s) : Tocilizumab

                            Therapeutic Area : Immunology

                            Highest Development Status : Approved FDF

                            Recipient : Biogen

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            02

                            Merck & Co

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                            Lead Product(s) : Trastuzumab Deruxtecan,Cisplatin,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Recipient : Daiichi Sankyo

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Enhertu Initiated in Patients with Previously Untreated HER2 Positive Gastric Cancer

                            Details : Enhertu (trastuzumab deruxtecan) in combination with fluoropyrimidine chemotherapy, pembrolizumab is being studied for unresectable, locally advanced or metastatic HER2 positive gastric or GEJ cancer.

                            Product Name : Enhertu

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            March 31, 2025

                            Lead Product(s) : Trastuzumab Deruxtecan,Cisplatin,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Recipient : Daiichi Sankyo

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Merck & Co

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                            Lead Product(s) : 21-valent Pneumococcal Conjugate Vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            EU Approves Merck's Capvaxive for Invasive Pneumococcal Disease Prevention

                            Details : Capvaxive (21-valent Pneumococcal Conjugate Vaccine) is a prophylactic vaccine candidate which is approved for the treatment of pneumococcal pneumonia in adults.

                            Product Name : Capvaxive

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            March 27, 2025

                            Lead Product(s) : 21-valent Pneumococcal Conjugate Vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Merck & Co

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                            Merck & Co

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                            Lead Product(s) : Islatravir,Doravirine

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Merck’s DOR/ISL Two-Drug Regimen Shows 48-Week HIV-1 Viral Suppression in Trials

                            Details : MK-8591A is a combination of islatravir and Doravirine which are being investigated as non-nucleoside reverse transcriptase translocation inhibitor of HIV-1.

                            Product Name : MK-8591A

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 12, 2025

                            Lead Product(s) : Islatravir,Doravirine

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Merck & Co

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                            German Wound Congress
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                            Merck & Co

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                            Lead Product(s) : Zilovertamab Vedotin,Cyclophosphamide,Rituximab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Merck Starts Phase 3 waveLINE-010 Study of Zilovertamab Vedotin in DLBCL

                            Details : MK-2140 (zilovertamab vedotin) is an investigational ADC that targets ROR1 receptor. It is being evaluated for the treatment of previously untreated patients with diffuse large b-cell lymphoma.

                            Product Name : MK-2140

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            February 06, 2025

                            Lead Product(s) : Zilovertamab Vedotin,Cyclophosphamide,Rituximab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Merck & Co

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                            Lead Product(s) : Sotatercept

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Merck Ends Hyperion Trial Early for WINREVAIR, Moves to Analysis

                            Details : Winrevair (sotatercept) is the first activin signaling inhibitor therapy, which is approved for the treatment of adults with pulmonary arterial hypertension.

                            Product Name : Winrevair

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            January 30, 2025

                            Lead Product(s) : Sotatercept

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Merck & Co

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                            German Wound Congress
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                            Merck & Co

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                            Lead Product(s) : Belzutifan

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            FDA Grants Priority Review to Merck’s Welireg for Advanced PPGL

                            Details : Welireg (belzutifan), an oral HIF-2α inhibitor, being evaluated for the treatment of adult and pediatric patients with advanced, unresectable, or metastatic pheochromocytoma and paraganglioma.

                            Product Name : Welireg

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            January 27, 2025

                            Lead Product(s) : Belzutifan

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Merck & Co

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                            Merck & Co

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                            Lead Product(s) : Pembrolizumab,Lenvatinib,Oxaliplatin

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Eisai

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Merck, Eisai Combo Misses Survival Goal in GI Cancer Trial

                            Details : Keytruda (Pembrolizumab) is a PD-1 inhibitor antibody, being evaluated with Lenvima (lenvatinib) for (HER2)-negative gastroesophageal adenocarcinoma.

                            Product Name : Keytruda

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            January 24, 2025

                            Lead Product(s) : Pembrolizumab,Lenvatinib,Oxaliplatin

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Eisai

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Merck & Co

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                            Merck & Co

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                            Lead Product(s) : HPV Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Merck’s GARDASIL® Receives Expanded Approval for Males in China

                            Details : Gardasil (recombinant human papillomavirus quadrivalent vaccine), has been approved in China for use in males 9-26 years of age to help prevent certain HPV-related cancers and diseases..

                            Product Name : Gardasil

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            January 08, 2025

                            Lead Product(s) : HPV Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Merck & Co

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                            Lead Product(s) : Sotatercept

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Merck Wins UK Approval for Lung Disease Drug Acquired in $11 Billion Deal

                            Details : Winrevair (sotatercept) is the first activin signaling inhibitor therapy, which is approved for the treatment of adults with pulmonary arterial hypertension.

                            Product Name : Winrevair

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            December 31, 2024

                            Lead Product(s) : Sotatercept

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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