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                          Therapeutic Area by Lead Product

                          Study Phase by Lead Product

                          Company by Lead Product

                          Top Deals by Deal Size (USD bn)

                          01

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : The proceeds will be used in Mesoblast’s lead product candidate Ryoncil (remestemcel-L) in the treatment of children with steroid-refractory acute graft versus host disease (SR-aGvHD).

                          Brand Name : Ryoncil

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          September 29, 2024

                          Lead Product(s) : Remestemcel-L

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase III

                          Sponsor : Gregory George

                          Deal Size : $50.0 million

                          Deal Type : Financing

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                          02

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : Ryoncil (remestemcel-l) have immunomodulatory properties to counteract the inflammatory processes in SRaGVHD by down-regulating the production of pro-inflammatory cytokines.

                          Brand Name : Ryoncil

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          July 23, 2024

                          Lead Product(s) : Remestemcel-L

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : Revascor (rexlemestrocel-L) is preparation of immunoselected and culture-expanded mesenchymal precursor cells. It is being evaluated for the treatment of moderate to severe chronic low back pain.

                          Brand Name : Revascor

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          July 21, 2024

                          Lead Product(s) : Rexlemestrocel-L,Hyaluronic Acid

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : Ryoncil (remestemcel-L) is an investigational therapy comprising mesenchymal stromal cells, for the treatment of adults with steroid-refractory acute graft versus host disease (SR-aGvHD).

                          Brand Name : Ryoncil

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          July 09, 2024

                          Lead Product(s) : Remestemcel-L

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : Prochymal (remestemcel-L) is an off-the-shelf suspension of ex-vivo cultured adult human mesenchymal stem cells, evaluated for pediatric patients with SR-aGVHD.

                          Brand Name : Prochymal

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          March 25, 2024

                          Lead Product(s) : Remestemcel-L

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : Revascor (rexlemestrocel-L) is an allogeneic preparation of immunoselected and culture-expanded mesenchymal precursor cells. It is being developed for hypoplastic left heart syndrome in children.

                          Brand Name : Revascor

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          February 14, 2024

                          Lead Product(s) : Rexlemestrocel-L

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : Revascor (rexlemestrocel-L) is a mesenchymal precursor cell therapy in phase 1/2 trials for treating Hypoplastic Left Heart Syndrome.

                          Brand Name : Revascor

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          January 18, 2024

                          Lead Product(s) : Rexlemestrocel-L

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : Revascor (rexlemestrocel-L) is an allogeneic preparation of immunoselected and culture-expanded mesenchymal precursor cells. It is under phase 1/2 clinical development for the treatment of Hypoplastic Left Heart Syndrome.

                          Brand Name : Revascor

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          November 26, 2023

                          Lead Product(s) : Rexlemestrocel-L

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : The agreement aims to develop a pivotal trial of Mesoblast’s lead product candidate Ryoncil (remestemcel-L) in the treatment of adults with steroid-refractory acute graft versus host disease (SR-aGvHD).

                          Brand Name : Ryoncil

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          November 21, 2023

                          Lead Product(s) : Remestemcel-L

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase III

                          Sponsor : BMT CTN

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          10

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : Ryoncil (remestemcel-l) have immunomodulatory properties to counteract the inflammatory processes in SRaGVHD by down-regulating the production of pro-inflammatory cytokines, increasing production of naturally occurring anti-inflammatory cells to involved...

                          Brand Name : Ryoncil

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          September 21, 2023

                          Lead Product(s) : Remestemcel-L

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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