Lead Product(s) : Methylbenzylamine
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Adaptive Research
Deal Size : Not Applicable
Deal Type : Not Applicable
Adaptive Research Enrolls Patients in AriBio’s Phase 3 POLARIS-AD Trial
Details : AR1001 is a phosphodiesterase-5 (PDE5) inhibitor being developed as an oral agent for the treatment of early Alzheimer’s disease.
Brand Name : AR1001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 30, 2024
Lead Product(s) : Methylbenzylamine
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Adaptive Research
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Methylbenzylamine
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
AriBio gets IND approval for Phase 3 Alzheimer’s trial in China
Details : AR1001 is a phosphodiesterase-5 (PDE5) inhibitor being developed as an investigational oral agent being investigated for the treatment of early Alzheimer’s disease.
Brand Name : AR1001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 14, 2024
Lead Product(s) : Methylbenzylamine
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Methylbenzylamine
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
AriBio Receives EMA Phase 3 Trial Authorization for AR1001 in Alzheimer’s Disease
Details : AR1001 is a phosphodiesterase-5 (PDE5) inhibitor being developed as an investigational oral agent being investigated for the treatment of early Alzheimer’s disease.
Brand Name : AR1001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 28, 2024
Lead Product(s) : Methylbenzylamine
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Methylbenzylamine
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : AR1001 is a blood-brain barrier penetrating small molecule known to inhibit neuron apoptosis and promote neurogenesis, increase neuroplasticity and increase autophagy activity to remove toxic proteins.
Brand Name : AR1001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 05, 2023
Lead Product(s) : Methylbenzylamine
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Methylbenzylamine
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
AriBio Co., Ltd. Announces the Successful Completion of Their End of Phase 2 Meeting With the USFDA
Details : Pre-clinical studies have confirmed neuroprotective effects of AR1001 via inhibiting neuron apoptosis and restoring synaptic plasticity, also has demonstrated notable effects against amyloid plaques and tau proteins via autophagy activation.
Brand Name : AR1001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 04, 2022
Lead Product(s) : Methylbenzylamine
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Methylbenzylamine
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Cleveland Clinic
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Positive Phase II trial reported for AR1001, the results confirmed the possibility of developing a unique oral disease-modifying treatment for AD that improves cognitive function. The Company will complete Phase III clinical trials of AR1001 within the n...
Brand Name : AR1001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 20, 2021
Lead Product(s) : Methylbenzylamine
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Cleveland Clinic
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Methylbenzylamine
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : SK Chemicals
Deal Size : Not Applicable
Deal Type : Not Applicable
AriBio Announces Completion of Enrollment in Phase 2 Alzheimer’s Study with AR1001
Details : AriBio completed enrollment in a Phase 2 study of AR1001, a first in class, orally dosed investigational drug for mild to moderate Alzheimer’s disease.
Brand Name : AR1001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 17, 2020
Lead Product(s) : Methylbenzylamine
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : SK Chemicals
Deal Size : Not Applicable
Deal Type : Not Applicable
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