Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Pravibismane
Therapeutic Area : Podiatry
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Microbion Reports Positive Phase 2 Pravibismane Data for Diabetic Foot Ulcers
Details : Microbion's lead drug candidate, MBN-101 (pravibismane), is the first product in this new class and has multiple novel modes of action, being developed for diabetic foot ulcer infections (DFI).
Product Name : MBN-101
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 13, 2024
Lead Product(s) : Pravibismane
Therapeutic Area : Podiatry
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Pravibismane
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Microbion's Pravibismane Granted Second FDA Orphan Drug Designation for NTM Infections
Details : MBN 101 (Pravibismane) is a small molecule antibacterial agent which is being evaluated in preclinical trials for the treatment of non-tuberculous mycobacterial (NTM) infections.
Product Name : MBN-101
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 30, 2024
Lead Product(s) : Pravibismane
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Pravibismane
Therapeutic Area : Podiatry
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : MBN-101 (pravibismane) is the first in a new class of anti-infective drugs demonstrating broad-spectrum potency against a wide range of multidrug-resistant bacteria, and biofilms ubiquitous in DFU infections.
Product Name : MBN-101
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 03, 2023
Lead Product(s) : Pravibismane
Therapeutic Area : Podiatry
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Pravibismane
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Microbion Corp. Granted US Patent for the Use of Inhaled Pravibismane for Pulmonary Infections
Details : MBN-101 (inhaled pravibismane) has received QIDP, Fast Track and Orphan drug designation from the USFDA for the treatment of pulmonary infections in patients with cystic fibrosis. Microbion has successfully completed non-clinical studies for the inhaled ...
Product Name : MBN-101
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 04, 2023
Lead Product(s) : Pravibismane
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Pravibismane
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : MBN-101 has been granted Qualified Infectious Disease Product (QIDP) designation and Fast Track designation by the US FDA for: (1) adjunctive treatment of moderate and severe diabetic foot ulcer infection; and (2) treatment of post-surgical orthopedic im...
Product Name : MBN-101
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 10, 2022
Lead Product(s) : Pravibismane
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Pravibismane
Therapeutic Area : Podiatry
Study Phase : Phase II
Sponsor : US Navy
Deal Size : $2.1 million
Deal Type : Funding
Details : Pravibismane (MBN-101), is the first in a new class of anti-infective drugs structurally unrelated to other clinically utilized antibiotics. With a novel mechanism of action, pravibismane shuts down bacterial ATP production thereby halting global bacteri...
Product Name : MBN-101
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
July 06, 2022
Lead Product(s) : Pravibismane
Therapeutic Area : Podiatry
Highest Development Status : Phase II
Sponsor : US Navy
Deal Size : $2.1 million
Deal Type : Funding
Lead Product(s) : Pravibismane
Therapeutic Area : Podiatry
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Pravibismane (MBN-101) shuts down bacterial ATP production thereby halting global bacterial cellular metabolism. Pravibismane exhibits broad-spectrum, potent in vitro activity against pathogens and their biofilms including MRSA, CRE, and multidrug resist...
Product Name : MBN-101
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 10, 2022
Lead Product(s) : Pravibismane
Therapeutic Area : Podiatry
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Pravibismane
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : MBN-101 (pravibismane) is first new class of anti-infective drugs with novel MOA, rapidly reduces bacterial ATP production in both planktonic and biofilm bacterial populations, thereby halting global bacterial cellular metabolism.
Product Name : MBN-101
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 11, 2022
Lead Product(s) : Pravibismane
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Pravibismane
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : MBN-101 (pravibismane) is first in a new class of anti-infective drugs structurally unrelated to other clinically utilized antibiotics. With a novel mechanism of action, pravibismane shuts down bacterial ATP production thereby halting global bacterial ce...
Product Name : MBN-101
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 06, 2022
Lead Product(s) : Pravibismane
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Pravibismane
Therapeutic Area : Infections and Infectious Diseases
Study Phase : IND Enabling
Sponsor : Cystic Fibrosis Foundation
Deal Size : $7.4 million
Deal Type : Funding
Details : This new funding of up to $1.8 million will directly support IND-enabling toxicology studies of pravibismane and is in addition to $5.6 million previously awarded by the Foundation, for a combined total of up to $7.4 million.
Product Name : MBN-101
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
February 22, 2021
Lead Product(s) : Pravibismane
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : IND Enabling
Sponsor : Cystic Fibrosis Foundation
Deal Size : $7.4 million
Deal Type : Funding