Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Psilocybine
Therapeutic Area : Neurology
Study Phase : IND Enabling
Sponsor : Otsuka Pharmaceutical
Deal Size : $59.2 million
Deal Type : Acquisition
Otsuka Pharmaceutical to Acquire Mindset Pharma
Details : Through the acquisition, Otsuka strengthens its pipeline in the area of psychiatric and neurological disorders by including, MSP-1014 (psilocybin), a new class of agonists that activate the serotonin 5-HT2A receptor.
Brand Name : MSP-1014
Molecule Type : Small molecule
Upfront Cash : $59.2 million
September 01, 2023
Lead Product(s) : Psilocybine
Therapeutic Area : Neurology
Highest Development Status : IND Enabling
Sponsor : Otsuka Pharmaceutical
Deal Size : $59.2 million
Deal Type : Acquisition
Lead Product(s) : MSP-1014
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : MSP-1014 is a differentiated psilocybin-based compound from Mindset’s Family 1 of novel, patent-pending psychedelic compounds. MSP-1014 was the first compound identified by the Company to progress towards human clinical trials.
Brand Name : MSP-1014
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 02, 2023
Lead Product(s) : MSP-1014
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Psilocybine
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : MSP-1014 is a differentiated psilocybin-based compound from Mindset’s Family 1 of novel, patent-pending psychedelic compounds. MSP-1014 was the first compound identified by the Company to progress towards human clinical trials.
Brand Name : MSP-1014
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 20, 2023
Lead Product(s) : Psilocybine
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Psilocybine
Therapeutic Area : Neurology
Study Phase : Undisclosed
Sponsor : PharmAla Biotech
Deal Size : Undisclosed
Deal Type : Agreement
Details : Under the sales agreement, PharmAla will be the exclusive global reseller of Mindset’s cGMP (i.e. pharmaceutical grade) psilocybin to appropriately licensed clinical researchers.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
November 16, 2022
Lead Product(s) : Psilocybine
Therapeutic Area : Neurology
Highest Development Status : Undisclosed
Sponsor : PharmAla Biotech
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : MSP-1014
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : MSP-1014 was also evaluated in a drug discrimination assay in which rats were trained to discriminate a psilocybin cue from saline. MSP-1014 displayed complete generalization to the psilocybin cue with a similar ED50 and duration of action (~4 hr) at equ...
Brand Name : MSP-1014
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 14, 2022
Lead Product(s) : MSP-1014
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Psilocin Prodrug
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Mindset Pharma Announces Poster Presentations at Two Upcoming Scientific Conferences
Details : MSP-1014 (psilocin prodrug), a second-generation psilocybin-like drug, demonstrated an improved efficacy, with reduced potential side effects and faster onset of action, and similar duration of effect compared to the first-generation drug candidate psilo...
Brand Name : MSP-1014
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 27, 2022
Lead Product(s) : Psilocin Prodrug
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Psilocybine
Therapeutic Area : Psychiatry/Psychology
Study Phase : IND Enabling
Sponsor : Cybin
Deal Size : $9.5 million
Deal Type : Licensing Agreement
Mindset Pharma Provides Strategic Intellectual Property License to Cybin
Details : Under the terms of the Agreement, Cybin will license intellectual property related to preclinical compounds within Mindset’s “Family 1” portfolio, excluding MSP-1014 (psilocybin), Mindset’s lead psychedelic drug candidate.
Brand Name : MSP-1014
Molecule Type : Small molecule
Upfront Cash : $0.5 million
September 27, 2022
Lead Product(s) : Psilocybine
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : IND Enabling
Sponsor : Cybin
Deal Size : $9.5 million
Deal Type : Licensing Agreement
Lead Product(s) : Psilocybine
Therapeutic Area : Psychiatry/Psychology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : In preclinical studies, MSP-1014, demonstrated an improved efficacy and safety profiles, with reduced potential side effects and faster onset of action, and similar duration of effect compared to the first-generation drug candidate psilocybin.
Brand Name : MSP-1014
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 14, 2022
Lead Product(s) : Psilocybine
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Non-tryptamine Psychedelic Derivatives
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Mindset’s scientists designed and developed three new, chemically distinct, small molecule non-tryptamine scaffolds, Families 6, 7 and 8. Mindset has filed provisional patent applications on these families, with favorable FTO searches.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 31, 2022
Lead Product(s) : Non-tryptamine Psychedelic Derivatives
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Otsuka Pharmaceutical
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : High-potency, short-acting, psilocybin-like novel analogues of psilocybin that exhibit a range of pharmacokinetic and pharmacodynamic improvements in pre-clinical studies for the treatment of CNS disorders.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 06, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Otsuka Pharmaceutical
Deal Size : Not Applicable
Deal Type : Not Applicable
LOOKING FOR A SUPPLIER?