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    [{"orgOrder":0,"company":"Mineralys Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Small molecule","year":"2022","type":"Not Applicable","leadProduct":"MLS-101","moa":"","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase II","graph3":"Mineralys Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Mineralys Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Mineralys Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Mineralys Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"D","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Small molecule","year":"2023","type":"Public Offering","leadProduct":"Lorundrostat","moa":"","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase 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Placement","leadProduct":"Lorundrostat","moa":"","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase III","graph3":"Mineralys Therapeutics","amount2":0.12,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0.12,"dosageForm":"Tablet","sponsorNew":"Mineralys Therapeutics \/ TCGX","highestDevelopmentStatusID":"10","companyTruncated":"Mineralys Therapeutics \/ TCGX"},{"orgOrder":0,"company":"Mineralys Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Lorundrostat","moa":"","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase III","graph3":"Mineralys Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"","sponsorNew":"Mineralys Therapeutics \/ Not 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Diseases","graph2":"Phase III","graph3":"Mineralys Therapeutics","amount2":0.17999999999999999,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0.28999999999999998,"dosageForm":"Oral Tablet","sponsorNew":"Mineralys Therapeutics \/ BofA Securities","highestDevelopmentStatusID":"10","companyTruncated":"Mineralys Therapeutics \/ BofA Securities"}]

    Find Clinical Drug Pipeline Developments & Deals by Mineralys Therapeutics

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                            01

                            Mineralys Therapeutics

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                            NextGen Biomed
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                            Mineralys Therapeutics

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                            Lead Product(s) : Lorundrostat

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : BofA Securities

                            Deal Size : $175.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Mineralys Prices $175M Underwritten Public Offering of Common Stock

                            Details : The net proceeds from the offering will be used to fund the clinical development of MT-4129 (lorundrostat). It is being evaluated for the treatment of Uncontrolled or Resistant Hypertension.

                            Product Name : MT-4129

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            March 11, 2025

                            Lead Product(s) : Lorundrostat

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : BofA Securities

                            Deal Size : $175.0 million

                            Deal Type : Public Offering

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                            02

                            Mineralys Therapeutics

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                            NextGen Biomed
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                            Mineralys Therapeutics

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                            NextGen Biomed
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                            Lead Product(s) : Lorundrostat

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : BofA Securities

                            Deal Size : $287.5 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Mineralys Therapeutics Announces Proposed Public Offering of Common Stock

                            Details : The net proceeds from the offering will be used to fund the clinical development of MT-4129 (lorundrostat). It is being evaluated for the treatment of Uncontrolled or Resistant Hypertension.

                            Product Name : MT-4129

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            March 10, 2025

                            Lead Product(s) : Lorundrostat

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : BofA Securities

                            Deal Size : $287.5 million

                            Deal Type : Public Offering

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                            03

                            Mineralys Therapeutics

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                            NextGen Biomed
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                            Mineralys Therapeutics

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                            NextGen Biomed
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                            Lead Product(s) : Lorundrostat

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Mineralys Reports Positive Lorundrostat Data in Uncontrolled Hypertension

                            Details : MLS-101 (lorundrostat) is a proprietary, orally administered, highly selective aldosterone synthase inhibitor being developed for the treatment of uncontrolled hypertension or resistant hypertension.

                            Product Name : MT-4129

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 10, 2025

                            Lead Product(s) : Lorundrostat

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Mineralys Therapeutics

                            U.S.A arrow
                            NextGen Biomed
                            Not Confirmed

                            Mineralys Therapeutics

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                            NextGen Biomed
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                            Lead Product(s) : Lorundrostat

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Mineralys Completes Enrollment in Explore-CKD Phase 2 Lorundrostat Trial

                            Details : MLS-101 (lorundrostat) is a proprietary, orally administered, highly selective aldosterone synthase inhibitor being developed for the treatment of uncontrolled hypertension or resistant hypertension.

                            Product Name : MT-4129

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            February 04, 2025

                            Lead Product(s) : Lorundrostat

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Mineralys Therapeutics

                            U.S.A arrow
                            NextGen Biomed
                            Not Confirmed

                            Mineralys Therapeutics

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                            NextGen Biomed
                            Not Confirmed
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                            Lead Product(s) : Lorundrostat

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Mineralys Announces Phase 2 Trial of Lorundrostat for Sleep Apnea and Hypertension

                            Details : MLS-101 (lorundrostat) is an oral highly selective aldosterone synthase inhibitor. It is being evaluated for the treatment of obstructive sleep apnea in patients with hypertension.

                            Product Name : MLS-101

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            January 08, 2025

                            Lead Product(s) : Lorundrostat

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Mineralys Therapeutics

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                            NextGen Biomed
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                            Mineralys Therapeutics

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                            NextGen Biomed
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                            Lead Product(s) : Lorundrostat

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Mineralys Completes Launch-HTN Trial Enrollment for Lorundrostat in Hypertension

                            Details : MLS-101 (lorundrostat) is a proprietary, orally administered, highly selective aldosterone synthase inhibitor being developed for the treatment of uncontrolled hypertension or resistant hypertension.

                            Product Name : MT-4129

                            Product Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 30, 2024

                            Lead Product(s) : Lorundrostat

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Mineralys Therapeutics

                            U.S.A arrow
                            NextGen Biomed
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                            Mineralys Therapeutics

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                            NextGen Biomed
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                            Lead Product(s) : Lorundrostat

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Mineralys Completes Target Enrollment in Lorundrostat Trial For Hypertension

                            Details : MLS-101 (lorundrostat) is a orally administered, highly selective aldosterone synthase inhibitor. It is being evaluated in phase 3 clinical trials for the treatment of uncontrolled hypertension.

                            Product Name : MLS-101

                            Product Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 25, 2024

                            Lead Product(s) : Lorundrostat

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Mineralys Therapeutics

                            U.S.A arrow
                            NextGen Biomed
                            Not Confirmed

                            Mineralys Therapeutics

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                            NextGen Biomed
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                            Lead Product(s) : Lorundrostat

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : TCGX

                            Deal Size : $120.0 million

                            Deal Type : Private Placement

                            DEALS_DEV arrow-down

                            Mineralys Therapeutics Announces $120 Million Private Placement Financing

                            Details : The company intends to use the net proceeds for the development of MLS-101 (lorundrostat) for the treatment of uncontrolled and resistant hypertension.

                            Product Name : MLS-101

                            Product Type : Small molecule

                            Upfront Cash : Undisclosed

                            February 08, 2024

                            Lead Product(s) : Lorundrostat

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : TCGX

                            Deal Size : $120.0 million

                            Deal Type : Private Placement

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                            09

                            Mineralys Therapeutics

                            U.S.A arrow
                            NextGen Biomed
                            Not Confirmed

                            Mineralys Therapeutics

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                            NextGen Biomed
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                            Lead Product(s) : Lorundrostat

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Mineralys Therapeutics Announces First Subject Dosed in Launch-HTN, the Second Pivotal Trial of Lorundrostat f...

                            Details : MLS-101 (lorundrostat) is a proprietary, orally administered, highly selective aldosterone synthase inhibitor. It is being evaluated in phase 3 clinical trials for the treatment of uncontrolled and resistant hypertension.

                            Product Name : MLS-101

                            Product Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 21, 2023

                            Lead Product(s) : Lorundrostat

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            Mineralys Therapeutics

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                            NextGen Biomed
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                            Mineralys Therapeutics

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                            NextGen Biomed
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                            Lead Product(s) : Lorundrostat

                            Therapeutic Area : Nephrology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Mineralys Therapeutics Announces Expansion of Planned Phase 2 Trial of Lorundrostat Alone and in Combination w...

                            Details : MLS-101 (lorundrostat) is a proprietary, orally administered, highly selective aldosterone synthase inhibitor being developed for the treatment of uncontrolled hypertension and chronic kidney disease.

                            Product Name : MLS-101

                            Product Type : Small molecule

                            Upfront Cash : Not Applicable

                            July 17, 2023

                            Lead Product(s) : Lorundrostat

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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