[{"orgOrder":0,"company":"Minghui Pharmaceutical","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"CHINA","productType":"Small molecule","year":"2023","type":"Not Applicable","leadProduct":"MH004","moa":"","graph1":"Dermatology","graph2":"Phase III","graph3":"Minghui Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Cream","sponsorNew":"Minghui Pharmaceutical \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"Minghui Pharmaceutical \/ Not Applicable"},{"orgOrder":0,"company":"Minghui Pharmaceutical","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"CHINA","productType":"Large molecule","year":"2023","type":"Not Applicable","leadProduct":"MHB018A","moa":"","graph1":"Immunology","graph2":"Phase I","graph3":"Minghui Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"","sponsorNew":"Minghui Pharmaceutical \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Minghui Pharmaceutical \/ Not Applicable"},{"orgOrder":0,"company":"Minghui Pharmaceutical","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"CHINA","productType":"Large molecule","year":"2023","type":"Not Applicable","leadProduct":"MHB018A","moa":"","graph1":"Immunology","graph2":"Phase I","graph3":"Minghui Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Injectable\/Injection","sponsorNew":"Minghui Pharmaceutical \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Minghui Pharmaceutical \/ Not Applicable"},{"orgOrder":0,"company":"Minghui Pharmaceutical","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Large molecule","year":"2023","type":"Not Applicable","leadProduct":"MHB036C","moa":"","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Minghui Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Minghui Pharmaceutical \/ Not Applicable","highestDevelopmentStatusID":"7","companyTruncated":"Minghui Pharmaceutical \/ Not Applicable"},{"orgOrder":0,"company":"Minghui Pharmaceutical","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"CHINA","productType":"Small molecule","year":"2023","type":"Not Applicable","leadProduct":"MH004","moa":"","graph1":"Dermatology","graph2":"Phase III","graph3":"Minghui Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Cream","sponsorNew":"Minghui Pharmaceutical \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"Minghui Pharmaceutical \/ Not Applicable"},{"orgOrder":0,"company":"Minghui Pharmaceutical","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"MHB088C","moa":"","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Minghui Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Minghui Pharmaceutical \/ Not Applicable","highestDevelopmentStatusID":"7","companyTruncated":"Minghui Pharmaceutical \/ Not Applicable"},{"orgOrder":0,"company":"Minghui Pharmaceutical","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"MHB088C","moa":"","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Minghui Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Minghui Pharmaceutical \/ Not Applicable","highestDevelopmentStatusID":"7","companyTruncated":"Minghui Pharmaceutical \/ Not Applicable"},{"orgOrder":0,"company":"Minghui Pharmaceutical","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"CHINA","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"MHB018A","moa":"","graph1":"Immunology","graph2":"Phase I\/ Phase II","graph3":"Minghui Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"","sponsorNew":"Minghui Pharmaceutical \/ Not Applicable","highestDevelopmentStatusID":"7","companyTruncated":"Minghui Pharmaceutical \/ Not Applicable"},{"orgOrder":0,"company":"Minghui Pharmaceutical","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"MHB039A","moa":"","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Minghui Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Minghui Pharmaceutical \/ Not Applicable","highestDevelopmentStatusID":"7","companyTruncated":"Minghui Pharmaceutical \/ Not Applicable"},{"orgOrder":0,"company":"Minghui Pharmaceutical","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Tofacitinib Etocomil","moa":"","graph1":"Dermatology","graph2":"Phase III","graph3":"Minghui Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"","sponsorNew":"Minghui Pharmaceutical \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"Minghui Pharmaceutical \/ Not Applicable"}]

Find Clinical Drug Pipeline Developments & Deals by Minghui Pharmaceutical

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Details : MH004 (tofacitinib etocomil) ointment 1.0%, a twice-daily pan-Jak inhibitor. It is being evaluated in late-stage clinical trial studies for the treating mild to moderate atopic dermatitis.

                          Brand Name : MH004

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          November 29, 2024

                          Lead Product(s) : Tofacitinib Etocomil

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Details : MHB039A, developed by Minghui Pharmaceutical, is a novel bispecific antibody targeting PD-1 and VEGF being developed in patients with relapsed/refractory solid tumors.

                          Brand Name : MHB039A

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          November 06, 2024

                          Lead Product(s) : MHB039A

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Details : MHB018A is a novel subcutaneous VHH-Fc fusion protein that targets the insulin-like growth factor-1 receptor (IGF-1R), a validated mechanism of action for Thyroid Eye Disease treatment.

                          Brand Name : MHB018A

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          October 22, 2024

                          Lead Product(s) : MHB018A

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Details : MHB088C is a novel B7-H3-targeting antibody-drug conjugate (ADC), which has demonstrated remarkable anti-tumor efficacy across various reccurent advanced cancer types.

                          Brand Name : MHB088C

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          May 08, 2024

                          Lead Product(s) : MHB088C

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Details : MHB088C is a novel B7-H3 antibody-drug conjugate incorporating a potent DNA topoisomerase I inhibitor. It is being evaluated for the treatment of recurrent or metastatic solid tumors.

                          Brand Name : MHB088C

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          May 08, 2024

                          Lead Product(s) : MHB088C

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Details : MH004 is the investigational topical cream,currently in phase 3 clinical study for targeting mild to moderate atopic dermatitis. The topline data of the phase 3 trial with the medical community and regulatory authorities in H2 2024.

                          Brand Name : MH004

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          August 17, 2023

                          Lead Product(s) : MH004

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Details : MHB036C is an antibody drug conjugate composed of a humanized anti-TROP-2 monoclonal antibody conjugated to Minghui's proprietary DNA topoisomerase I inhibitor via a cleavable linker, investigated for metastatic solid tumors.

                          Brand Name : MHB036C

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          June 20, 2023

                          Lead Product(s) : MHB036C

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Details : MHB018A is a novel fusion protein of humanized single domain IGF-1R antibody and human Fc, which showed 3~5 times greater ligand blocking activities than other known IGF-1R antibodies for both IGF-1 and IGF-2.

                          Brand Name : MHB018A

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          May 24, 2023

                          Lead Product(s) : MHB018A

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Details : MHB018A is a novel fusion protein of humanized single domain IGF-1R antibody and human Fc, which showed 3~5 times greater ligand blocking activities than other known IGF-1R antibodies for both IGF-1 and IGF-2.

                          Brand Name : MHB018A

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          May 23, 2023

                          Lead Product(s) : MHB018A

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Details : MH004 cream is a topical cream containing a JAK inhibitor, it is intended to be used for treatment of multiple dermatologic autoimmune diseases including atopic dermatitis.

                          Brand Name : MH004

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          April 14, 2023

                          Lead Product(s) : MH004

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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