Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Mirvetuximab Soravtansine
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
AbbVie Receives Positive CHMP Opinion for Mirvetuximab Soravtansine in Ovarian Cancer
Details : Elahere (mirvetuximab soravtansine) is a first-in-class antibody-drug conjugate (ADC) approved for folate receptor alpha (FRα) positive platinum-resistant ovarian cancer.
Brand Name : Elahere
Molecule Type : Large molecule
Upfront Cash : Not Applicable
September 20, 2024
Lead Product(s) : Mirvetuximab Soravtansine
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Mirvetuximab Soravtansine
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
FDA Grants Full Approval for ELAHERE® for Certain Ovarian Cancer Patients
Details : Elahere (mirvetuximab soravtansine) is a first-in-class antibody-drug conjugate (ADC) approved for folate receptor alpha (FRα) positive platinum-resistant ovarian cancer.
Brand Name : Elahere
Molecule Type : Large molecule
Upfront Cash : Not Applicable
March 22, 2024
Lead Product(s) : Mirvetuximab Soravtansine
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Mirvetuximab Soravtansine
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : AbbVie Inc
Deal Size : $10,100.0 million
Deal Type : Acquisition
AbbVie Completes Acquisition of ImmunoGen
Details : The acquisition accelerates AbbVie's presence in the solid tumor space by adding Elahere (mirvetuximab soravtansine-gynx), an ADC approved for FRα-positive platinum-resistant ovarian cancer.
Brand Name : Elahere
Molecule Type : Large molecule
Upfront Cash : $10,100.0 million
February 12, 2024
Lead Product(s) : Mirvetuximab Soravtansine
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : AbbVie Inc
Deal Size : $10,100.0 million
Deal Type : Acquisition
Lead Product(s) : Mirvetuximab Soravtansine
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Elahere (mirvetuximab soravtansine-gynx) is an ADC. The antibody is a chimeric IgG1 directed against folate receptor alpha and DM4, is a microtubule inhibitor attached to the antibody via a cleavable linker. It is being developed for FRα-positive platin...
Brand Name : Elahere
Molecule Type : Large molecule
Upfront Cash : Not Applicable
September 28, 2023
Lead Product(s) : Mirvetuximab Soravtansine
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Mirvetuximab Soravtansine
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Takeda Pharmaceutical
Deal Size : Undisclosed
Deal Type : Collaboration
ImmunoGen Announces Collaboration with Takeda to Develop and Commercialize ELAHERE® in Japan
Details : Under the agreement, ImmunoGen has retained production rights and will supply product for development and commercial use in Japan and Takeda will receive license to develop and commercialize ELAHERE in Japan and is responsible for all regulatory filings ...
Brand Name : Elahere
Molecule Type : Large molecule
Upfront Cash : $34.0 million
August 28, 2023
Lead Product(s) : Mirvetuximab Soravtansine
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Takeda Pharmaceutical
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Mirvetuximab Soravtansine
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Jefferies
Deal Size : $373.8 million
Deal Type : Public Offering
Details : ImmunoGen intends to use the proceeds to fund its operations, including global commercialization activities, supply of ELAHERE® (mirvetuximab soravtansine-gynx) drug product, pipeline research and development activities, business development, and capita...
Brand Name : Elahere
Molecule Type : Large molecule
Upfront Cash : Undisclosed
May 09, 2023
Lead Product(s) : Mirvetuximab Soravtansine
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Jefferies
Deal Size : $373.8 million
Deal Type : Public Offering
Lead Product(s) : Mirvetuximab Soravtansine
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Jefferies
Deal Size : $325.0 million
Deal Type : Public Offering
ImmunoGen Announces Pricing of Upsized Public Offering of Common Stock
Details : ImmunoGen intends to use the net proceeds to fund its operations, including, but not limited to, global commercialization activities, supply of ELAHERE® (mirvetuximab soravtansine-gynx) drug product, clinical trial activities, pipeline research and deve...
Brand Name : Elahere
Molecule Type : Large molecule
Upfront Cash : Undisclosed
May 04, 2023
Lead Product(s) : Mirvetuximab Soravtansine
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Jefferies
Deal Size : $325.0 million
Deal Type : Public Offering
Lead Product(s) : Mirvetuximab Soravtansine
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Elahere (mirvetuximab soravtansine-gynx) is an ADC. The antibody is a chimeric IgG1 directed against folate receptor alpha and DM4, is a microtubule inhibitor attached to the antibody via a cleavable linker. It is being developed for FRα-positive platin...
Brand Name : Elahere
Molecule Type : Large molecule
Upfront Cash : Not Applicable
May 03, 2023
Lead Product(s) : Mirvetuximab Soravtansine
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Mirvetuximab Soravtansine
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : In the intent-to-treat population, statistically significant improvement in number of patients achieving 15-point improvement in gastrointestinal symptoms was observed at week 8/9 in patients treated with IMGN853 (mirvetuximab) versus chemotherapy (31.7%...
Brand Name : IMGN853
Molecule Type : Large molecule
Upfront Cash : Not Applicable
September 11, 2022
Lead Product(s) : Mirvetuximab Soravtansine
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Mirvetuximab Soravtansine
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Mirvetuximab soravtansine (IMGN853) is a first-in-class ADC comprising a folate receptor alpha-binding antibody, cleavable linker, and the maytansinoid payload DM4, a potent tubulin-targeting agent, to kill the targeted cancer cells.
Brand Name : IMGN853
Molecule Type : Large molecule
Upfront Cash : Not Applicable
May 26, 2022
Lead Product(s) : Mirvetuximab Soravtansine
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable