Active Filter(s):
Details:
Under the terms of the agreement, the companies will jointly conduct research and preclinical development activities to identify novel monovalent small molecules that modulate target proteins through activation, stabilization or degradation as potential development candidates.
Lead Product(s): Undisclosed
Therapeutic Area: Technology Product Name: Undisclosed
Highest Development Status: Discovery Product Type: Small molecule
Recipient: Generian Pharmaceuticals
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Collaboration February 08, 2023
Details:
ACMSD is a key enzyme involved in the de novo synthesis of NAD+, which is critical to mitochondrial function via maintenance of cellular redox state. TLC-065, is being advanced for the treatment of a range of metabolic and inflammatory liver and kidney disorders.
Lead Product(s): TLC-065
Therapeutic Area: Hepatology (Liver, Pancreatic, Gall Bladder) Product Name: TLC-065
Highest Development Status: IND Enabling Product Type: Undisclosed
Partner/Sponsor/Collaborator: OrsoBio
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Acquisition November 02, 2022