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                            01

                            Moderna Therapeutics

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                            Lead Product(s) : CAR-M Therapy

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Recipient : Carisma Therapeutics

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Carisma Highlights Pre-Clinical Data On Anti-GPC3 CAR-M Therapy for Liver Cancer

                            Details : Anti-GPC3 in vivo chimeric antigen receptor macrophage and monocyte therapy being investigated for the treament of GPC3-positive hepatocellular carcinoma.

                            Brand Name : Undisclosed

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            November 08, 2024

                            Lead Product(s) : CAR-M Therapy

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Recipient : Carisma Therapeutics

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Moderna Therapeutics

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                            Lead Product(s) : mRNA-4157,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Merck & Co

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Merck and Moderna Start Phase 3 Trial for V940 with KEYTRUDA in Lung Cancer

                            Details : V940 (mRNA-4157) is a novel investigational messenger RNA (mRNA)-based individualized neoantigen therapy. It is under clinical development for the treatment of non-small cell lung cancer.

                            Brand Name : V940

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            October 28, 2024

                            Lead Product(s) : mRNA-4157,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Merck & Co

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Moderna Therapeutics

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                            Lead Product(s) : mRNA-1403

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            UK’s First Norovirus mRNA Vaccine Trial Launched

                            Details : mRNA-1403 is an mRNA vaccine which is currently being evaluated to prevent moderate to severe acute gastroenteritis caused by norovirus.

                            Brand Name : mRNA-1403

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            October 24, 2024

                            Lead Product(s) : mRNA-1403

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Moderna Therapeutics

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                            Lead Product(s) : mRNA-1403

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Moderna Begins Phase 3 Trial of mRNA Norovirus Vaccine, mRNA-1403

                            Details : mRNA-1403 is an mRNA vaccine which is currently being evaluated to prevent moderate to severe acute gastroenteritis caused by norovirus.

                            Brand Name : mRNA-1403

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            September 30, 2024

                            Lead Product(s) : mRNA-1403

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Moderna Therapeutics

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                            Lead Product(s) : Covid-19 Vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved

                            Sponsor : Cenra Healthcare

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Moderna Partners with Cenra For mRNA Vaccine Promotion in Taiwan

                            Details : The agreement aims for the co-promotion of Moderna's mRNA respiratory vaccine portfolio in Taiwan, including Moderna's COVID-19 vaccine, Spikevax.

                            Brand Name : Spikevax

                            Molecule Type : Vaccine

                            Upfront Cash : Undisclosed

                            September 30, 2024

                            Lead Product(s) : Covid-19 Vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved

                            Sponsor : Cenra Healthcare

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            06

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                            Lead Product(s) : Covid-19 Vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Moderna Gains Health Canada Approval for Updated COVID-19 Vaccine

                            Details : Spikevax is a COVID-19 vaccine developed by Moderna that utilizes messenger RNA (mRNA) technology to stimulate an immune response against the SARS-CoV-2 virus.

                            Brand Name : Spikevax

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            September 17, 2024

                            Lead Product(s) : Covid-19 Vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Moderna Therapeutics

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                            Lead Product(s) : CAR-M-based Therapy

                            Therapeutic Area : Immunology

                            Study Phase : Discovery Platform

                            Recipient : Carisma Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Expanded Collaboration

                            DEALS_DEV arrow-down

                            Carisma and Moderna Expand Collaboration On in Vivo CAR-M Autoimmune Therapies

                            Details : Under this expanded collaboration,Carisma and Moderna will leverage Carisma's CAR-M technology and Moderna's mRNA/LNP platform to develop novel approaches for the treatment of autoimmune disease.

                            Brand Name : Undisclosed

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            September 10, 2024

                            Lead Product(s) : CAR-M-based Therapy

                            Therapeutic Area : Immunology

                            Highest Development Status : Discovery Platform

                            Recipient : Carisma Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Expanded Collaboration

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                            08

                            Moderna Therapeutics

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Technology

                            Study Phase : Discovery Platform

                            Recipient : Leveragen

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Leveragen Announces Collaboration with Moderna to Advance Antibody Technology

                            Details : Under the agreement, Leveragen will employ its proprietary antibody discovery platform to generate a panel of optimized binding modules against therapeutic targets selected by Moderna.

                            Brand Name : Undisclosed

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            July 30, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Technology

                            Highest Development Status : Discovery Platform

                            Recipient : Leveragen

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            09

                            Moderna Therapeutics

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                            Lead Product(s) : Covid-19 Vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved

                            Sponsor : Mitsubishi Tanabe Pharma

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Moderna and Mitsubishi Tanabe Sign Agreement for mRNA Vaccines in Japan

                            Details : Moderna and Mitsubishi entered into a joint agreement regarding the co-promotion of Moderna's mRNA respiratory vaccine portfolio in Japan, including Moderna's COVID-19 vaccine, Spikevax.

                            Brand Name : Spikevax

                            Molecule Type : Vaccine

                            Upfront Cash : Undisclosed

                            July 08, 2024

                            Lead Product(s) : Covid-19 Vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved

                            Sponsor : Mitsubishi Tanabe Pharma

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            10

                            Moderna Therapeutics

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                            Lead Product(s) : mRNA-1010

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : BARDA

                            Deal Size : $176.0 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Bird flu concern prompts US to award Moderna $176 million for vaccine development

                            Details : The funding aims to support the late-stage development of the Moderna mRNA-1010 vaccine, facilitating its licensure as a pre-pandemic vaccine against the H5 influenza virus.

                            Brand Name : mRNA-1010

                            Molecule Type : Vaccine

                            Upfront Cash : Undisclosed

                            July 02, 2024

                            Lead Product(s) : mRNA-1010

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : BARDA

                            Deal Size : $176.0 million

                            Deal Type : Funding

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