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    [{"orgOrder":0,"company":"Molecular Partners","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Large molecule","year":"2020","type":"Not Applicable","leadProduct":"DARPin","moa":"ACE2","graph1":"Infections and Infectious Diseases","graph2":"Preclinical","graph3":"Molecular Partners","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"","sponsorNew":"Molecular Partners \/ Not Applicable","highestDevelopmentStatusID":"4","companyTruncated":"Molecular Partners \/ Not Applicable"},{"orgOrder":0,"company":"Molecular Partners","sponsor":"AGC Biologics","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Large molecule","year":"2020","type":"Collaboration","leadProduct":"MP0420","moa":"","graph1":"Infections and Infectious 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Morgan"},{"orgOrder":0,"company":"Molecular Partners","sponsor":"AbbVie Inc","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"","productType":"Large molecule","year":"2021","type":"Partnership","leadProduct":"Abicipar Pegol","moa":"VEGFA","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Molecular Partners","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Intravitreal Injection","sponsorNew":"Molecular Partners \/ AbbVie","highestDevelopmentStatusID":"10","companyTruncated":"Molecular Partners \/ AbbVie"},{"orgOrder":0,"company":"Molecular Partners","sponsor":"Novartis Pharmaceuticals Corporation","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Large molecule","year":"2021","type":"Not Applicable","leadProduct":"Ensovibep","moa":"SARS-CoV-2 spike protein","graph1":"Infections and Infectious Diseases","graph2":"Phase 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Partners \/ Molecular Partners","highestDevelopmentStatusID":"9","companyTruncated":"Molecular Partners \/ Molecular Partners"},{"orgOrder":0,"company":"Molecular Partners","sponsor":"Amgen Inc","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"MP0310","moa":"CD137","graph1":"Oncology","graph2":"Phase I","graph3":"Molecular Partners","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Molecular Partners \/ Amgen","highestDevelopmentStatusID":"6","companyTruncated":"Molecular Partners \/ Amgen"},{"orgOrder":0,"company":"Molecular Partners","sponsor":"Novartis Pharmaceuticals Corporation","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"Ensovibep","moa":"SARS-CoV-2 spike protein","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Molecular Partners","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Molecular Partners \/ Novartis","highestDevelopmentStatusID":"10","companyTruncated":"Molecular Partners \/ Novartis"},{"orgOrder":0,"company":"Molecular Partners","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2023","type":"Not Applicable","leadProduct":"MP0533","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"Molecular Partners","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Molecular Partners \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Molecular Partners \/ Not Applicable"}]

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                            01

                            Molecular Partners

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                            Lead Product(s) : MP0533

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Molecular Partners Initiates Clinical Study of Trispecific Candidate Mp0533 for The Treatment of Acute Myeloid...

                            Details : MP0533 is a T-cell engager, leveraging the cell surface protein CD3 as a powerful immune activator, complemented by novel control mechanisms designed to help direct CD3-mediated cytotoxicity with heightened precision. It is being studied for AML.

                            Brand Name : MP0533

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            January 16, 2023

                            Lead Product(s) : MP0533

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Molecular Partners

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                            Lead Product(s) : MP0310

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Amgen Inc

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Molecular Partners to Regain Global Rights for MP0310 from Amgen

                            Details : MP0310 is a dual-targeted compound, targeting both FAP and 4-1BB, that has the potential to activate T-cells and other immune cells, specifically in the tumor microenvironment, aiming to avoid systemic side effects associated with 4-1BB activation.

                            Brand Name : MP0310

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            April 26, 2022

                            Lead Product(s) : MP0310

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Amgen Inc

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Molecular Partners

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                            Lead Product(s) : Ensovibep

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II/ Phase III

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Molecular Partners Announces Presentation of the EMPATHY Study of Ensovibep for the Treatment of COVID-19 at E...

                            Details : MP0420 (ensovibep) is a COVID-19 antiviral therapeutic candidate designed specifically to inactivate SARS-CoV-2 – the virus that causes COVID-19 – with extremely high potency that is preserved against novel variants.

                            Brand Name : MP0420

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            April 23, 2022

                            Lead Product(s) : Ensovibep

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Molecular Partners

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                            Molecular Partners

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                            Lead Product(s) : Ensovibep,Remdesivir,Sotrovimab

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II/ Phase III

                            Recipient : Novartis Pharmaceuticals Corporation

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Novartis and Molecular Partners Report Positive Topline Data from Phase 2 study for Ensovibep (MP0420), a DARP...

                            Details : Topline results from the randomized EMPATHY Part A study in acute COVID-19 ambulatory patients comparing single intravenous doses of MP0420/SKO136 (ensovibep), a DARPin antiviral therapeutic candidate vs. placebo, met the primary endpoint of viral load r...

                            Brand Name : MP0420

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            January 10, 2022

                            Lead Product(s) : Ensovibep,Remdesivir,Sotrovimab

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II/ Phase III

                            Recipient : Novartis Pharmaceuticals Corporation

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Molecular Partners

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                            Molecular Partners

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                            Lead Product(s) : Ensovibep,Remdesivir,Sotrovimab

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Molecular Partners Confirms Ensovibep Retains Neutralization of Omicron Variant of SARS-CoV-2 in Preclinical S...

                            Details : Laboratory studies using full Omicron pseudovirus confirm MP0420 (ensovibep), maintains ability to neutralize the variant with very high potency, relative to substantial reductions in neutralizing potency across numerous anti-SARS-CoV-2 antibody drugs.

                            Brand Name : MP0420

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            December 12, 2021

                            Lead Product(s) : Ensovibep,Remdesivir,Sotrovimab

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Molecular Partners

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                            Molecular Partners

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                            Lead Product(s) : Ensovibep,Remdesivir,Sotrovimab

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II/ Phase III

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Molecular Partners Provides Update from ACTIV-3 Global Clinical Study of Ensovibep in Patients Hospitalized wi...

                            Details : In vitro data to-date demonstrate that ensovibep retains potency in inhibiting all known SARS-CoV-2 variants of concern, including the Delta variants. Ensovibep is the lead therapeutic candidate in Molecular Partners’ infectious disease pipeline.

                            Brand Name : MP0420

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            November 16, 2021

                            Lead Product(s) : Ensovibep,Remdesivir,Sotrovimab

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Molecular Partners

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                            Molecular Partners

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                            Lead Product(s) : Ensovibep

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II/ Phase III

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Molecular Partners Present Data Demonstrating Successful Inhibition of Covid19 Viral Variants with Ensovibep a...

                            Details : In the results presented, neutralization assays demonstrate ensovibep’s ability to potently neutralize SARS-CoV-2 when testing the Wuhan or a reference strain.

                            Brand Name : MP0420

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            October 20, 2021

                            Lead Product(s) : Ensovibep

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Molecular Partners

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                            Lead Product(s) : DARPin-conjugated Radioligand Therapies

                            Therapeutic Area : Oncology

                            Study Phase : Discovery

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : $580.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Molecular Partners Announces Collaboration with Novartis to Develop DARPin-Conjugated Radioligand Therapeutic ...

                            Details : The collaboration will combine Molecular Partners’ industry-leading ability to rapidly generate high-affinity DARPins and the RLT capabilities and expertise of Novartis. DARPins have great potential to enable robust, tumor-specific delivery of radiolig...

                            Brand Name : DARPin-RLTs

                            Molecule Type : Large molecule

                            Upfront Cash : $20.0 million

                            October 14, 2021

                            Lead Product(s) : DARPin-conjugated Radioligand Therapies

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : $580.0 million

                            Deal Type : Acquisition

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                            09

                            Molecular Partners

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                            Molecular Partners

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                            Lead Product(s) : Abicipar Pegol

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase III

                            Sponsor : AbbVie Inc

                            Deal Size : Undisclosed

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            Molecular Partners to Regain Global Rights to Abicipar

                            Details : Abicipar is a long-acting anti-VEGF DARPin® molecule which was invented by Molecular Partners and initially licensed to Allergan in 2011.

                            Brand Name : AGN-150998

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            August 09, 2021

                            Lead Product(s) : Abicipar Pegol

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase III

                            Sponsor : AbbVie Inc

                            Deal Size : Undisclosed

                            Deal Type : Partnership

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                            10

                            Molecular Partners

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                            Lead Product(s) : Ensovibep

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II/ Phase III

                            Sponsor : J.P. Morgan

                            Deal Size : $63.8 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Molecular Partners Announces Pricing of Initial Public Offering of American Depositary Shares in the United St...

                            Details : MP0420 is a clinical-stage candidate that is subject to an option and license agreement with Novartis AG to develop, manufacture and commercialize Molecular Partners’ infectious disease program.

                            Brand Name : MP0420

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            June 15, 2021

                            Lead Product(s) : Ensovibep

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : J.P. Morgan

                            Deal Size : $63.8 million

                            Deal Type : Public Offering

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