[{"orgOrder":0,"company":"MBrace Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Large Molecule","year":"2023","type":"Inapplicable","leadProduct":"Monomethyl Auristatin E","moa":"EphA5 MMAE","graph1":"Oncology","graph2":"Phase I","graph3":"MBrace Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"MBrace Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"MBrace Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"MBrace Therapeutics","sponsor":"TPG Life Sciences Innovations","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Large Molecule","year":"2023","type":"Series B Financing","leadProduct":"Monomethyl Auristatin E","moa":"EphA5 MMAE","graph1":"Oncology","graph2":"Phase I","graph3":"MBrace Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"MBrace Therapeutics \/ TPG Life Sciences Innovations","highestDevelopmentStatusID":"6","companyTruncated":"MBrace Therapeutics \/ TPG Life Sciences Innovations"}]

Find Clinical Drug Pipeline Developments & Deals for Monomethyl Auristatin E

Menu
Xls
Filters Filter
×
FILTER:
filter
Company Name
    filter

    Year

      filter

      DEALS // DEV.

        filter

        Country

          filter
          Sponsor
            filter

            Therapeutic Area

              filter

              Study Phase

                filter

                Deal Type

                  filter

                  Product Type

                    filter

                    Dosage Form

                      filter

                      Lead Product

                        filter

                        Target

                          Loading...

                          Therapeutic Area by Lead Product

                          Study Phase by Lead Product

                          Company by Lead Product

                          Top Deals by Deal Size (USD bn)

                          01

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : MBRC-101 (monomethyl auristatin E)is a novel, targeted ADC which targets the EphA5 receptor tyrosine kinase. It is under phase 1 clinical development for the treatment of multiple solid tumor cancers, including breast, non-small cell lung and other solid...

                          Product Name : MBRC-101

                          Product Type : Other Large Molecule

                          Upfront Cash : Inapplicable

                          December 19, 2023

                          Lead Product(s) : Monomethyl Auristatin E

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          blank

                          02

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : The financing will be used to support clinical development programs, including a first-in-human clinical trial of lead investigational ADC, MBRC-101, which targets the EphA5 receptor tyrosine kinase.

                          Product Name : MBRC-101

                          Product Type : Other Large Molecule

                          Upfront Cash : Undisclosed

                          November 14, 2023

                          Lead Product(s) : Monomethyl Auristatin E

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : TPG Life Sciences Innovations

                          Deal Size : $85.0 million

                          Deal Type : Series B Financing

                          blank