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                          01

                          Discovery on Target
                          Not Confirmed
                          Discovery on Target
                          Not Confirmed

                          Details : MNPR-101-Zr is a radioactive uPAR modulating candidate, which is currently being evaluated for the treatment of uPAR-expressing triple-negative breast cancer and other tumors.

                          Brand Name : MNPR-101-Zr

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          September 12, 2024

                          Lead Product(s) : MNPR-101-Zr

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Discovery on Target
                          Not Confirmed
                          Discovery on Target
                          Not Confirmed

                          Details : MNPR-101-Zr is a radioactive uPAR modulating candidate, which is currently being evaluated for the treatment of uPAR-expressing triple-negative breast cancer and other tumors.

                          Brand Name : MNPR-101-Zr

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          August 14, 2024

                          Lead Product(s) : MNPR-101-Zr

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Discovery on Target
                          Not Confirmed
                          Discovery on Target
                          Not Confirmed

                          Details : MNPR-101-Zr is a radioactive uPAR modulating candidate, which is currently being evaluated for the treatment of uPAR-expressing triple-negative breast cancer and other tumors.

                          Brand Name : MNPR-101-Zr

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          July 09, 2024

                          Lead Product(s) : MNPR-101-Zr

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Discovery on Target
                          Not Confirmed
                          Discovery on Target
                          Not Confirmed

                          Details : NorthStar will provide Monopar with the powerful therapeutic radioisotope actinium-225 (Ac-225) in its lead MNPR-101, radio-immuno-therapeutic (RIT) for the treatment of advanced cancers.

                          Brand Name : MNPR-101

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          June 11, 2024

                          Lead Product(s) : MNPR-101

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : NorthStar Medical Radioisotopes

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          05

                          Discovery on Target
                          Not Confirmed
                          Discovery on Target
                          Not Confirmed

                          Details : MNPR-101-Zr is a radioactive large molecule drug candidate, which is currently being evaluated for the treatment of uPAR-expressing triple-negative breast cancer.

                          Brand Name : MNPR-101-Zr

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          April 10, 2024

                          Lead Product(s) : MNPR-101-Zr

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Discovery on Target
                          Not Confirmed
                          Discovery on Target
                          Not Confirmed

                          Details : MNPR-101-Zr is a zirconium-89 labeled version of MNPR-101, Monopar’s proprietary first-in-class humanized monoclonal antibody that is highly selective against uPAR. It is being developed for the treatment of triple-negative breast, colorectal, & pancre...

                          Brand Name : MNPR-101-Zr

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          February 27, 2024

                          Lead Product(s) : MNPR-101-Zr

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : North Star Processing, LLC.

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Discovery on Target
                          Not Confirmed
                          Discovery on Target
                          Not Confirmed

                          Details : MNPR-101-Zr is a zirconium-89 labeled version of MNPR-101, Monopar’s proprietary first-in-class humanized monoclonal antibody that is highly selective against uPAR. It is being developed for the treatment of triple-negative breast, colorectal, & pancre...

                          Brand Name : MNPR-101-Zr

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          February 20, 2024

                          Lead Product(s) : MNPR-101-Zr

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Discovery on Target
                          Not Confirmed
                          Discovery on Target
                          Not Confirmed

                          Details : MNPR-201 (camsirubicin) is a novel proprietary analog of widely used cancer drug doxorubicin. Doxorubicin is used to treat adult and pediatric solid and hematologic cancers including breast, gastric, ovarian and bladder cancer, soft tissue sarcomas, leuk...

                          Brand Name : MNPR-201

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          August 08, 2023

                          Lead Product(s) : Camsirubicin,Pegfilgrastim

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Discovery on Target
                          Not Confirmed
                          Discovery on Target
                          Not Confirmed

                          Details : The collaboration aims to evaluate radiopharmaceutical versions of MNPR-101 RIT in several aggressive cancers. MNPR-101 is a novel, first-in-class humanized monoclonal antibody to the urokinase Plasminogen Activator Receptor (uPAR).

                          Brand Name : MNPR-101 RIT

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          July 11, 2023

                          Lead Product(s) : MNPR-101,Actinium-225

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Cancer Science Institute of Singapore

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          10

                          Discovery on Target
                          Not Confirmed
                          Discovery on Target
                          Not Confirmed

                          Details : Camsirubicin is a novel proprietary analog of the widely used cancer drug doxorubicin. Doxorubicin is used to treat adult and pediatric solid and hematologic cancers including breast, gastric, ovarian and bladder cancer, soft tissue sarcomas, leukemias a...

                          Brand Name : MNPR-201

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          June 01, 2023

                          Lead Product(s) : Camsirubicin,Pegfilgrastim

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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